Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10011086HBVENSG00000069431.14protein_codingABCC9NoNo10060O60706
TVIS10019878HBVENSG00000069431.14protein_codingABCC9NoNo10060O60706
TVIS30032267HIVENSG00000069431.14protein_codingABCC9NoNo10060O60706
TVIS30032268HIVENSG00000069431.14protein_codingABCC9NoNo10060O60706
TVIS20050784HPVENSG00000069431.14protein_codingABCC9NoNo10060O60706
TVIS20050485HPVENSG00000069431.14protein_codingABCC9NoNo10060O60706
TVIS20050615HPVENSG00000069431.14protein_codingABCC9NoNo10060O60706
TVIS44009671HTLV-1ENSG00000069431.14protein_codingABCC9NoNo10060O60706
TCGA Plot Options
Drug Information
GeneABCC9
DrugBank IDDB01016
Drug NameGlyburide
Target IDBE0000469
UniProt IDO60706
Regulation Typemodulator
PubMed IDs12145099; 14672537; 15023854; 16845255; 17294036
CitationsHambrock A, Loffler-Walz C, Quast U: Glibenclamide binding to sulphonylurea receptor subtypes: dependence on adenine nucleotides. Br J Pharmacol. 2002 Aug;136(7):995-1004.@@Rainbow RD, James M, Hudman D, Al Johi M, Singh H, Watson PJ, Ashmole I, Davies NW, Lodwick D, Norman RI: Proximal C-terminal domain of sulphonylurea receptor 2A interacts with pore-forming Kir6 subunits in KATP channels. Biochem J. 2004 Apr 1;379(Pt 1):173-81.@@Felsch H, Lange U, Hambrock A, Loffler-Walz C, Russ U, Carroll WA, Gopalakrishnan M, Quast U: Interaction of a novel dihydropyridine K+ channel opener, A-312110, with recombinant sulphonylurea receptors and KATP channels: comparison with the cyanoguanidine P1075. Br J Pharmacol. 2004 Apr;141(7):1098-105. Epub 2004 Mar 15.@@Zhao JL, Yang YJ, You SJ, Jing ZC, Wu YJ, Cheng JL, Gao RL: Pretreatment with fosinopril or valsartan reduces myocardial no-reflow after acute myocardial infarction and reperfusion. Coron Artery Dis. 2006 Aug;17(5):463-9.@@Wang YH, Zheng HY, Qin NL, Yu SB, Liu SY: Involvement of ATP-sensitive potassium channels in proliferation and differentiation of rat preadipocytes. Sheng Li Xue Bao. 2007 Feb 25;59(1):8-12.
GroupsApproved
Direct ClassificationBenzenesulfonamides
SMILESCOC1=C(C=C(Cl)C=C1)C(=O)NCCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1
PathwaysGlibenclamide Action Pathway
PharmGKBPA449782
ChEMBLCHEMBL472