| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44008537 | HTLV-1 | ENSG00000023330.15 | protein_coding | ALAS1 | No | No | 211 | P13196 Q5JAM2 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ALAS1 |
|---|---|
| DrugBank ID | DB00145 |
| Drug Name | Glycine |
| Target ID | BE0000409 |
| UniProt ID | P13196 |
| Regulation Type | substrate |
| PubMed IDs | 17469798; 17578005 |
| Citations | Turbeville TD, Zhang J, Hunter GA, Ferreira GC: Histidine 282 in 5-aminolevulinate synthase affects substrate binding and catalysis. Biochemistry. 2007 May 22;46(20):5972-81. Epub 2007 May 1.@@He XM, Zhou J, Cheng Y, Fan J: [Purification and production of the extracellular 5-aminolevulinate from recombiniant Escherichia coli expressing yeast ALAS]. Sheng Wu Gong Cheng Xue Bao. 2007 May;23(3):520-4. |
| Groups | Approved; Nutraceutical; Vet_approved |
| Direct Classification | Alpha amino acids |
| SMILES | NCC(O)=O |
| Pathways | gamma-Glutamyltranspeptidase Deficiency; Lesch-Nyhan Syndrome (LNS); Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); Molybdenum Cofactor Deficiency; AICA-Ribosiduria; Purine Nucleoside Phosphorylase Deficiency; gamma-Glutamyltransferase Deficiency; Hyperprolinemia Type II; Glutamate Metabolism; Adenine Phosphoribosyltransferase Deficiency (APRT); Mercaptopurine Action Pathway; 2-Hydroxyglutric Aciduria (D and L Form); L-Arginine:Glycine Amidinotransferase Deficiency; Hyperinsulinism-Hyperammonemia Syndrome; Congenital Bile Acid Synthesis Defect Type II; Porphyrin Metabolism; Prolidase Deficiency (PD); Glycine and Serine Metabolism; Carnitine Synthesis; Adenosine Deaminase Deficiency; Methionine Metabolism; Bile Acid Biosynthesis; Hyperprolinemia Type I; Cystathionine beta-Synthase Deficiency; Arginine and Proline Metabolism; 27-Hydroxylase Deficiency; Sarcosine Oncometabolite Pathway; Purine Metabolism; Gout or Kelley-Seegmiller Syndrome; Ammonia Recycling |
| PharmGKB | PA449789 |
| ChEMBL | CHEMBL773 |
