| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20026795 | HPV | ENSG00000188822.8 | protein_coding | CNR2 | No | No | 1269 | P34972 |
| TVIS44037433 | HTLV-1 | ENSG00000188822.8 | protein_coding | CNR2 | No | No | 1269 | P34972 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CNR2 |
|---|---|
| DrugBank ID | DB00486 |
| Drug Name | Nabilone |
| Target ID | BE0000095 |
| UniProt ID | P34972 |
| Regulation Type | partial agonist |
| PubMed IDs | 11786493; 17450170; 17139494; 15221424; 11698062 |
| Citations | Conti S, Costa B, Colleoni M, Parolaro D, Giagnoni G: Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat. Br J Pharmacol. 2002 Jan;135(1):181-7.@@Mendizabal VE, Adler-Graschinsky E: Cannabinoids as therapeutic agents in cardiovascular disease: a tale of passions and illusions. Br J Pharmacol. 2007 Jun;151(4):427-40. Epub 2007 Apr 23.@@Davis M, Maida V, Daeninck P, Pergolizzi J: The emerging role of cannabinoid neuromodulators in symptom management. Support Care Cancer. 2007 Jan;15(1):63-71. Epub 2006 Dec 1.@@Kraft B, Kress HG: [Cannabinoids and the immune system. Of men, mice and cells]. Schmerz. 2004 Jun;18(3):203-10.@@Darmani NA: The cannabinoid CB1 receptor antagonist SR 141716A reverses the antiemetic and motor depressant actions of WIN 55, 212-2. Eur J Pharmacol. 2001 Oct 26;430(1):49-58. |
| Groups | Approved; Investigational |
| Direct Classification | Naphthopyranones |
| SMILES | [H][C@@]12CC(=O)CC[C@@]1([H])C(C)(C)OC1=CC(=CC(O)=C21)C(C)(C)CCCCCC |
| Pathways | |
| PharmGKB | PA164746998 |
| ChEMBL | CHEMBL947 |
