| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20063059 | HPV | ENSG00000179142.2 | protein_coding | CYP11B2 | No | No | 1585 | P19099 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CYP11B2 |
|---|---|
| DrugBank ID | DB11837 |
| Drug Name | Osilodrostat |
| Target ID | BE0003542 |
| UniProt ID | P19099 |
| Regulation Type | inhibitor |
| PubMed IDs | 27481775 |
| Citations | Weldon SM, Cerny MA, Gueneva-Boucheva K, Cogan D, Guo X, Moss N, Parmentier JH, Richman JR, Reinhart GA, Brown NF: Selectivity of BI 689648, a Novel, Highly Selective Aldosterone Synthase Inhibitor: Comparison with FAD286 and LCI699 in Nonhuman Primates. J Pharmacol Exp Ther. 2016 Oct;359(1):142-50. doi: 10.1124/jpet.116.236463. Epub 2016 Aug 1. |
| Groups | Approved; Investigational |
| Direct Classification | Benzonitriles |
| SMILES | FC1=C(C=CC(=C1)C#N)[C@H]1CCC2=CN=CN12 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL3099695 |
