| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10036834 | HBV | ENSG00000147099.21 | protein_coding | HDAC8 | No | No | 55869 | Q9BY41 |
| TVIS10034458 | HBV | ENSG00000147099.21 | protein_coding | HDAC8 | No | No | 55869 | Q9BY41 |
| TVIS10036988 | HBV | ENSG00000147099.21 | protein_coding | HDAC8 | No | No | 55869 | Q9BY41 |
| TVIS10044410 | HBV | ENSG00000147099.21 | protein_coding | HDAC8 | No | No | 55869 | Q9BY41 |
| TVIS30009951 | HIV | ENSG00000147099.21 | protein_coding | HDAC8 | No | No | 55869 | Q9BY41 |
| TVIS30073246 | HIV | ENSG00000147099.21 | protein_coding | HDAC8 | No | No | 55869 | Q9BY41 |
| TVIS30073247 | HIV | ENSG00000147099.21 | protein_coding | HDAC8 | No | No | 55869 | Q9BY41 |
| TVIS20007595 | HPV | ENSG00000147099.21 | protein_coding | HDAC8 | No | No | 55869 | Q9BY41 |
| TVIS44007853 | HTLV-1 | ENSG00000147099.21 | protein_coding | HDAC8 | No | No | 55869 | Q9BY41 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HDAC8 |
|---|---|
| DrugBank ID | DB01593 |
| Drug Name | Zinc |
| Target ID | BE0001608 |
| UniProt ID | Q9BY41 |
| Regulation Type | cofactor |
| PubMed IDs | 16681389 |
| Citations | Gantt SL, Gattis SG, Fierke CA: Catalytic activity and inhibition of human histone deacetylase 8 is dependent on the identity of the active site metal ion. Biochemistry. 2006 May 16;45(19):6170-8. |
| Groups | Approved; Investigational |
| Direct Classification | Homogeneous transition metal compounds |
| SMILES | [Zn] |
| Pathways | Dihydropyrimidinase Deficiency; Rofecoxib Action Pathway; Losartan Action Pathway; AICA-Ribosiduria; Canavan Disease; Quinapril Action Pathway; Alkaptonuria; Eprosartan Action Pathway; gamma-Glutamyltransferase Deficiency; Pterine Biosynthesis; Sulindac Action Pathway; Rescinnamine Action Pathway; Piroxicam Action Pathway; Nabumetone Action Pathway; 2-Hydroxyglutric Aciduria (D and L Form); beta-Ureidopropionase Deficiency; Vitamin B6 Metabolism; Retinol Metabolism; Valsartan Action Pathway; Valdecoxib Action Pathway; Irbesartan Action Pathway; Adenosine Deaminase Deficiency; Hawkinsinuria; Methionine Metabolism; Ramipril Action Pathway; Benazepril Action Pathway; beta-Alanine Metabolism; Aspartate Metabolism; Diclofenac Action Pathway; Galactosemia |
| PharmGKB | PA451956 |
| ChEMBL | CHEMBL1201279 |
