| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30087253 | HIV | ENSG00000135750.15 | protein_coding | KCNK1 | No | No | 3775 | O00180 |
| TVIS30026922 | HIV | ENSG00000135750.15 | protein_coding | KCNK1 | No | No | 3775 | O00180 |
| TVIS20017395 | HPV | ENSG00000135750.15 | protein_coding | KCNK1 | No | No | 3775 | O00180 |
| TVIS44024517 | HTLV-1 | ENSG00000135750.15 | protein_coding | KCNK1 | No | No | 3775 | O00180 |
| TVIS44018631 | HTLV-1 | ENSG00000135750.15 | protein_coding | KCNK1 | No | No | 3775 | O00180 |
| TVIS44014504 | HTLV-1 | ENSG00000135750.15 | protein_coding | KCNK1 | No | No | 3775 | O00180 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | KCNK1 |
|---|---|
| DrugBank ID | DB00908 |
| Drug Name | Quinidine |
| Target ID | BE0000154 |
| UniProt ID | O00180 |
| Regulation Type | inhibitor |
| PubMed IDs | 8605869; 9003761 |
| Citations | Lesage F, Guillemare E, Fink M, Duprat F, Lazdunski M, Romey G, Barhanin J: TWIK-1, a ubiquitous human weakly inward rectifying K+ channel with a novel structure. EMBO J. 1996 Mar 1;15(5):1004-11.@@Fink M, Duprat F, Lesage F, Reyes R, Romey G, Heurteaux C, Lazdunski M: Cloning, functional expression and brain localization of a novel unconventional outward rectifier K+ channel. EMBO J. 1996 Dec 16;15(24):6854-62. |
| Groups | Approved; Investigational |
| Direct Classification | Cinchona alkaloids |
| SMILES | [H][C@@]12CCN(C[C@@H]1C=C)[C@]([H])(C2)[C@@H](O)C1=C2C=C(OC)C=CC2=NC=C1 |
| Pathways | Quinidine Action Pathway |
| PharmGKB | PA451209 |
| ChEMBL | CHEMBL1294 |
