| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS46000241 | BKPyv | ENSG00000105486.15 | protein_coding | LIG1 | No | No | 3978 | F5GZ28 P18858 |
| TVIS30010618 | HIV | ENSG00000105486.15 | protein_coding | LIG1 | No | No | 3978 | F5GZ28 P18858 |
| TVIS30048978 | HIV | ENSG00000105486.15 | protein_coding | LIG1 | No | No | 3978 | F5GZ28 P18858 |
| TVIS30048979 | HIV | ENSG00000105486.15 | protein_coding | LIG1 | No | No | 3978 | F5GZ28 P18858 |
| TVIS30048980 | HIV | ENSG00000105486.15 | protein_coding | LIG1 | No | No | 3978 | F5GZ28 P18858 |
| TVIS30048981 | HIV | ENSG00000105486.15 | protein_coding | LIG1 | No | No | 3978 | F5GZ28 P18858 |
| TVIS30048982 | HIV | ENSG00000105486.15 | protein_coding | LIG1 | No | No | 3978 | F5GZ28 P18858 |
| TVIS30048983 | HIV | ENSG00000105486.15 | protein_coding | LIG1 | No | No | 3978 | F5GZ28 P18858 |
| TVIS30048984 | HIV | ENSG00000105486.15 | protein_coding | LIG1 | No | No | 3978 | F5GZ28 P18858 |
| TVIS30048985 | HIV | ENSG00000105486.15 | protein_coding | LIG1 | No | No | 3978 | F5GZ28 P18858 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | LIG1 |
|---|---|
| DrugBank ID | DB01280 |
| Drug Name | Nelarabine |
| Target ID | BE0000199 |
| UniProt ID | P18858 |
| Regulation Type | inhibitor |
| PubMed IDs | 18035189; 18473971 |
| Citations | Buie LW, Epstein SS, Lindley CM: Nelarabine: a novel purine antimetabolite antineoplastic agent. Clin Ther. 2007 Sep;29(9):1887-99.@@Curbo S, Karlsson A: Nelarabine: a new purine analog in the treatment of hematologic malignancies. Rev Recent Clin Trials. 2006 Sep;1(3):185-92. |
| Groups | Approved; Investigational |
| Direct Classification | Purine nucleosides |
| SMILES | COC1=NC(N)=NC2=C1N=CN2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O |
| Pathways | |
| PharmGKB | PA164752425 |
| ChEMBL | CHEMBL1201112 |
