| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30019485 | HIV | ENSG00000126067.12 | protein_coding | PSMB2 | Yes | No | 5690 | A0A087WVV1 B7Z478 P49721 |
| TVIS30023171 | HIV | ENSG00000126067.12 | protein_coding | PSMB2 | Yes | No | 5690 | A0A087WVV1 B7Z478 P49721 |
| TVIS20033288 | HPV | ENSG00000126067.12 | protein_coding | PSMB2 | Yes | No | 5690 | A0A087WVV1 B7Z478 P49721 |
| TVIS20048030 | HPV | ENSG00000126067.12 | protein_coding | PSMB2 | Yes | No | 5690 | A0A087WVV1 B7Z478 P49721 |
| TVIS44043525 | HTLV-1 | ENSG00000126067.12 | protein_coding | PSMB2 | Yes | No | 5690 | A0A087WVV1 B7Z478 P49721 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PSMB2 |
|---|---|
| DrugBank ID | DB08889 |
| Drug Name | Carfilzomib |
| Target ID | BE0002349 |
| UniProt ID | P49721 |
| Regulation Type | inhibitor |
| PubMed IDs | 17591945 |
| Citations | Kuhn DJ, Chen Q, Voorhees PM, Strader JS, Shenk KD, Sun CM, Demo SD, Bennett MK, van Leeuwen FW, Chanan-Khan AA, Orlowski RZ: Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma. Blood. 2007 Nov 1;110(9):3281-90. Epub 2007 Jun 25. |
| Groups | Approved; Investigational |
| Direct Classification | Oligopeptides |
| SMILES | CC(C)C[C@H](NC(=O)[C@H](CCC1=CC=CC=C1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |
| Pathways | |
| PharmGKB | PA166165203 |
| ChEMBL | CHEMBL451887 |
