| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10033171 | HBV | ENSG00000096717.12 | protein_coding | SIRT1 | No | No | 23411 | B0QZ35 E9PC49 Q96EB6 |
| TVIS44035877 | HTLV-1 | ENSG00000096717.12 | protein_coding | SIRT1 | No | No | 23411 | B0QZ35 E9PC49 Q96EB6 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SIRT1 |
|---|---|
| DrugBank ID | DB13978 |
| Drug Name | Selisistat |
| Target ID | BE0002461 |
| UniProt ID | Q96EB6 |
| Regulation Type | inhibitor |
| PubMed IDs | 16354677 |
| Citations | Solomon JM, Pasupuleti R, Xu L, McDonagh T, Curtis R, DiStefano PS, Huber LJ: Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage. Mol Cell Biol. 2006 Jan;26(1):28-38. doi: 10.1128/MCB.26.1.28-38.2006. |
| Groups | Experimental |
| Direct Classification | |
| SMILES | NC(=O)C1CCCC2=C1NC1=C2C=C(Cl)C=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL420311 |
