| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30082168 | HIV | ENSG00000184012.14 | protein_coding | TMPRSS2 | No | No | 7113 | O15393 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TMPRSS2 |
|---|---|
| DrugBank ID | DB13729 |
| Drug Name | Camostat |
| Target ID | BE0009920 |
| UniProt ID | O15393 |
| Regulation Type | inhibitor |
| PubMed IDs | 32142651 |
| Citations | Hoffmann M, Kleine-Weber H, Schroeder S, Kruger N, Herrler T, Erichsen S, Schiergens TS, Herrler G, Wu NH, Nitsche A, Muller MA, Drosten C, Pohlmann S: SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor. Cell. 2020 Apr 16;181(2):271-280.e8. doi: 10.1016/j.cell.2020.02.052. Epub 2020 Mar 5. |
| Groups | Experimental |
| Direct Classification | Depsides and depsidones |
| SMILES | CN(C)C(=O)COC(=O)CC1=CC=C(OC(=O)C2=CC=C(NC(N)=N)C=C2)C=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL590799 |
