| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10037924 | HBV | ENSG00000128918.15 | protein_coding | ALDH1A2 | No | No | 8854 | O94788 |
| TVIS10038228 | HBV | ENSG00000128918.15 | protein_coding | ALDH1A2 | No | No | 8854 | O94788 |
| TVIS10037141 | HBV | ENSG00000128918.15 | protein_coding | ALDH1A2 | No | No | 8854 | O94788 |
| TVIS10027389 | HBV | ENSG00000128918.15 | protein_coding | ALDH1A2 | No | No | 8854 | O94788 |
| TVIS10039378 | HBV | ENSG00000128918.15 | protein_coding | ALDH1A2 | No | No | 8854 | O94788 |
| TVIS10024790 | HBV | ENSG00000128918.15 | protein_coding | ALDH1A2 | No | No | 8854 | O94788 |
| TVIS10053832 | HBV | ENSG00000128918.15 | protein_coding | ALDH1A2 | No | No | 8854 | O94788 |
| TVIS10053833 | HBV | ENSG00000128918.15 | protein_coding | ALDH1A2 | No | No | 8854 | O94788 |
| TVIS30038427 | HIV | ENSG00000128918.15 | protein_coding | ALDH1A2 | No | No | 8854 | O94788 |
| TVIS30038428 | HIV | ENSG00000128918.15 | protein_coding | ALDH1A2 | No | No | 8854 | O94788 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ALDH1A2 |
|---|---|
| DrugBank ID | DB00755 |
| Drug Name | Tretinoin |
| Target ID | BE0000513 |
| UniProt ID | O94788 |
| Regulation Type | substrate |
| PubMed IDs | 15069081; 15299009; 15366004; 15950488; 15950969 |
| Citations | Mic FA, Sirbu IO, Duester G: Retinoic acid synthesis controlled by Raldh2 is required early for limb bud initiation and then later as a proximodistal signal during apical ectodermal ridge formation. J Biol Chem. 2004 Jun 18;279(25):26698-706. Epub 2004 Apr 6.@@Bordelon T, Montegudo SK, Pakhomova S, Oldham ML, Newcomer ME: A disorder to order transition accompanies catalysis in retinaldehyde dehydrogenase type II. J Biol Chem. 2004 Oct 8;279(41):43085-91. Epub 2004 Aug 7.@@Mic FA, Molotkov A, Molotkova N, Duester G: Raldh2 expression in optic vesicle generates a retinoic acid signal needed for invagination of retina during optic cup formation. Dev Dyn. 2004 Oct;231(2):270-7.@@Doxakis E, Davies AM: Retinoic acid negatively regulates GDNF and neurturin receptor expression and responsiveness in embryonic chicken sympathetic neurons. Mol Cell Neurosci. 2005 Aug;29(4):617-27.@@Everts HB, Sundberg JP, Ong DE: Immunolocalization of retinoic acid biosynthesis systems in selected sites in rat. Exp Cell Res. 2005 Aug 15;308(2):309-19. |
| Groups | Approved; Investigational; Nutraceutical |
| Direct Classification | |
| SMILES | CC(C=CC1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O |
| Pathways | Retinol Metabolism; Vitamin A Deficiency |
| PharmGKB | PA164746900 |
| ChEMBL | CHEMBL38 |
