Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30071911HIVENSG00000136807.14protein_codingCDK9NoNo1025P50750
TVIS30071912HIVENSG00000136807.14protein_codingCDK9NoNo1025P50750
TVIS44031380HTLV-1ENSG00000136807.14protein_codingCDK9NoNo1025P50750
TCGA Plot Options
Drug Information
GeneCDK9
DrugBank IDDB15442
Drug NameTrilaciclib
Target IDBE0002207
UniProt IDP50750
Regulation Typeinhibitor
PubMed IDs26826116
CitationsBisi JE, Sorrentino JA, Roberts PJ, Tavares FX, Strum JC: Preclinical Characterization of G1T28: A Novel CDK4/6 Inhibitor for Reduction of Chemotherapy-Induced Myelosuppression. Mol Cancer Ther. 2016 May;15(5):783-93. doi: 10.1158/1535-7163.MCT-15-0775. Epub 2016 Jan 29.
GroupsApproved; Investigational
Direct Classification
SMILESCN1CCN(CC1)C1=CN=C(NC2=NC3=C(C=C4N3C3(CCCCC3)CNC4=O)C=N2)C=C1
Pathways
PharmGKB
ChEMBLCHEMBL3894860