| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20037322 | HPV | ENSG00000145451.13 | protein_coding | GLRA3 | No | No | 8001 | O75311 Q9UPF3 |
| TVIS44008850 | HTLV-1 | ENSG00000145451.13 | protein_coding | GLRA3 | No | No | 8001 | O75311 Q9UPF3 |
| TVIS44038681 | HTLV-1 | ENSG00000145451.13 | protein_coding | GLRA3 | No | No | 8001 | O75311 Q9UPF3 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | GLRA3 |
|---|---|
| DrugBank ID | DB00466 |
| Drug Name | Picrotoxin |
| Target ID | BE0000414 |
| UniProt ID | O75311 |
| Regulation Type | antagonist |
| PubMed IDs | 17714449 |
| Citations | Yang Z, Cromer BA, Harvey RJ, Parker MW, Lynch JW: A proposed structural basis for picrotoxinin and picrotin binding in the glycine receptor pore. J Neurochem. 2007 Oct;103(2):580-9. Epub 2007 Aug 20. |
| Groups | Experimental |
| Direct Classification | Furopyrans |
| SMILES | [H][C@@]12OC(=O)[C@@]34OC3C[C@@](O)(C3[C@@H](C1OC3=O)C(C)=C)[C@@]24C.[H][C@@]12C[C@@]3(O)C4[C@@H](C(OC4=O)[C@@]4([H])OC(=O)[C@]1(O2)[C@@]34C)C(C)(C)O |
| Pathways | |
| PharmGKB | PA164777007 |
| ChEMBL | CHEMBL1908342 |
