Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30028077HIVENSG00000148672.10protein_codingGLUD1NoNo2746E9KL48
P00367
TVIS20018467HPVENSG00000148672.10protein_codingGLUD1NoNo2746E9KL48
P00367
TVIS20018468HPVENSG00000148672.10protein_codingGLUD1NoNo2746E9KL48
P00367
TVIS20022201HPVENSG00000148672.10protein_codingGLUD1NoNo2746E9KL48
P00367
TVIS20022246HPVENSG00000148672.10protein_codingGLUD1NoNo2746E9KL48
P00367
TCGA Plot Options
Drug Information
GeneGLUD1
DrugBank IDDB00756
Drug NameHexachlorophene
Target IDBE0000180
UniProt IDP00367
Regulation Typeinhibitor
PubMed IDs19531491; 570044
CitationsLi M, Smith CJ, Walker MT, Smith TJ: Novel inhibitors complexed with glutamate dehydrogenase: allosteric regulation by control of protein dynamics. J Biol Chem. 2009 Aug 21;284(34):22988-3000. doi: 10.1074/jbc.M109.020222. Epub 2009 Jun 15.@@Wang JL, Buhler DR: Inhibition of dehydrogenase enzymes by hexachlorophene. Biochem Pharmacol. 1978;27(24):2947-53.
GroupsApproved; Withdrawn
Direct ClassificationDiphenylmethanes
SMILESOC1=C(CC2=C(O)C(Cl)=CC(Cl)=C2Cl)C(Cl)=C(Cl)C=C1Cl
Pathways
PharmGKBPA449871
ChEMBLCHEMBL496