| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30067740 | HIV | ENSG00000105835.13 | protein_coding | NAMPT | No | No | 10135 | P43490 |
| TVIS30067741 | HIV | ENSG00000105835.13 | protein_coding | NAMPT | No | No | 10135 | P43490 |
| TVIS30067742 | HIV | ENSG00000105835.13 | protein_coding | NAMPT | No | No | 10135 | P43490 |
| TVIS20014546 | HPV | ENSG00000105835.13 | protein_coding | NAMPT | No | No | 10135 | P43490 |
| TVIS20014547 | HPV | ENSG00000105835.13 | protein_coding | NAMPT | No | No | 10135 | P43490 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | NAMPT |
|---|---|
| DrugBank ID | DB12980 |
| Drug Name | CHS-828 |
| Target ID | BE0002413 |
| UniProt ID | P43490 |
| Regulation Type | inhibitor |
| PubMed IDs | 21144000 |
| Citations | Olesen UH, Petersen JG, Garten A, Kiess W, Yoshino J, Imai S, Christensen MK, Fristrup P, Thougaard AV, Bjorkling F, Jensen PB, Nielsen SJ, Sehested M: Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase. BMC Cancer. 2010 Dec 12;10:677. doi: 10.1186/1471-2407-10-677. |
| Groups | Investigational |
| Direct Classification | Phenol ethers |
| SMILES | ClC1=CC=C(OCCCCCCNC(NC#N)=NC2=CC=NC=C2)C=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL17289 |
