| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30072831 | HIV | ENSG00000130234.13 | protein_coding | ACE2 | No | No | 59272 | Q9BYF1 |
| TVIS20013361 | HPV | ENSG00000130234.13 | protein_coding | ACE2 | No | No | 59272 | Q9BYF1 |
| TVIS20035516 | HPV | ENSG00000130234.13 | protein_coding | ACE2 | No | No | 59272 | Q9BYF1 |
| TVIS44028007 | HTLV-1 | ENSG00000130234.13 | protein_coding | ACE2 | No | No | 59272 | Q9BYF1 |
| TVIS44028008 | HTLV-1 | ENSG00000130234.13 | protein_coding | ACE2 | No | No | 59272 | Q9BYF1 |
| TVIS44028009 | HTLV-1 | ENSG00000130234.13 | protein_coding | ACE2 | No | No | 59272 | Q9BYF1 |
| TVIS44028010 | HTLV-1 | ENSG00000130234.13 | protein_coding | ACE2 | No | No | 59272 | Q9BYF1 |
| TVIS44034783 | HTLV-1 | ENSG00000130234.13 | protein_coding | ACE2 | No | No | 59272 | Q9BYF1 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ACE2 |
|---|---|
| DrugBank ID | DB09019 |
| Drug Name | Bromhexine |
| Target ID | BE0000982 |
| UniProt ID | Q9BYF1 |
| Regulation Type | binder |
| PubMed IDs | 32995775; 33045350 |
| Citations | Olaleye OA, Kaur M, Onyenaka CC: Ambroxol Hydrochloride Inhibits the Interaction between Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein's Receptor Binding Domain and Recombinant Human ACE2. bioRxiv. 2020 Sep 14. doi: 10.1101/2020.09.13.295691.@@Alkotaji M: Azithromycin and ambroxol as potential pharmacotherapy for SARS-CoV-2. Int J Antimicrob Agents. 2020 Dec;56(6):106192. doi: 10.1016/j.ijantimicag.2020.106192. Epub 2020 Oct 10. |
| Groups | Approved |
| Direct Classification | Phenylmethylamines |
| SMILES | CN(CC1=CC(Br)=CC(Br)=C1N)C1CCCCC1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL253376 |
