| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10040030 | HBV | ENSG00000151632.18 | protein_coding | AKR1C2 | No | No | 1646 | B4DK69 P52895 |
| TVIS10059666 | HBV | ENSG00000151632.18 | protein_coding | AKR1C2 | No | No | 1646 | B4DK69 P52895 |
| TVIS30027108 | HIV | ENSG00000151632.18 | protein_coding | AKR1C2 | No | No | 1646 | B4DK69 P52895 |
| TVIS30027109 | HIV | ENSG00000151632.18 | protein_coding | AKR1C2 | No | No | 1646 | B4DK69 P52895 |
| TVIS30027110 | HIV | ENSG00000151632.18 | protein_coding | AKR1C2 | No | No | 1646 | B4DK69 P52895 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | AKR1C2 |
|---|---|
| DrugBank ID | DB06777 |
| Drug Name | Chenodeoxycholic acid |
| Target ID | BE0000622 |
| UniProt ID | P52895 |
| Regulation Type | substrate |
| PubMed IDs | 8486699 |
| Citations | Stolz A, Hammond L, Lou H, Takikawa H, Ronk M, Shively JE: cDNA cloning and expression of the human hepatic bile acid-binding protein. A member of the monomeric reductase gene family. J Biol Chem. 1993 May 15;268(14):10448-57. |
| Groups | Approved |
| Direct Classification | Dihydroxy bile acids, alcohols and derivatives |
| SMILES | [H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(O)=O |
| Pathways | Congenital Bile Acid Synthesis Defect Type II; Familial Hypercholanemia (FHCA); Bile Acid Biosynthesis; Zellweger Syndrome; Congenital Bile Acid Synthesis Defect Type III; 27-Hydroxylase Deficiency; Cerebrotendinous Xanthomatosis (CTX) |
| PharmGKB | PA165958403 |
| ChEMBL | CHEMBL240597 |
