| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20009422 | HPV | ENSG00000132965.10 | protein_coding | ALOX5AP | No | No | 241 | A0A087WW23 P20292 |
| TVIS20051418 | HPV | ENSG00000132965.10 | protein_coding | ALOX5AP | No | No | 241 | A0A087WW23 P20292 |
| TVIS20044890 | HPV | ENSG00000132965.10 | protein_coding | ALOX5AP | No | No | 241 | A0A087WW23 P20292 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ALOX5AP |
|---|---|
| DrugBank ID | DB16346 |
| Drug Name | Veliflapon |
| Target ID | BE0002382 |
| UniProt ID | P20292 |
| Regulation Type | inhibitor |
| PubMed IDs | 19876784; 7741044; 11908571 |
| Citations | Sampson AP: FLAP inhibitors for the treatment of inflammatory diseases. Curr Opin Investig Drugs. 2009 Nov;10(11):1163-72.@@Hatzelmann A, Fruchtmann R, Mohrs KH, Raddatz S, Matzke M, Pleiss U, Keldenich J, Muller-Peddinghaus R: Mode of action of the leukotriene synthesis (FLAP) inhibitor BAY X 1005: implications for biological regulation of 5-lipoxygenase. Agents Actions. 1994 Nov;43(1-2):64-8. doi: 10.1007/BF02005767.@@He W, Pelletier JP, Martel-Pelletier J, Laufer S, Di Battista JA: Synthesis of interleukin 1beta, tumor necrosis factor-alpha, and interstitial collagenase (MMP-1) is eicosanoid dependent in human osteoarthritis synovial membrane explants: interactions with antiinflammatory cytokines. J Rheumatol. 2002 Mar;29(3):546-53. |
| Groups | Investigational |
| Direct Classification | |
| SMILES | OC(=O)[C@H](C1CCCC1)C1=CC=C(OCC2=NC3=C(C=CC=C3)C=C2)C=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL88712 |
