| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44013062 | HTLV-1 | ENSG00000101180.17 | protein_coding | HRH3 | No | No | 11255 | Q9Y5N1 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HRH3 |
|---|---|
| DrugBank ID | DB05381 |
| Drug Name | Histamine |
| Target ID | BE0000968 |
| UniProt ID | Q9Y5N1 |
| Regulation Type | agonist |
| PubMed IDs | 16599255; 16715497; 17575572; 17652997 |
| Citations | Petroianu G, Arafat K, Sasse BC, Stark H: Multiple enzyme inhibitions by histamine H3 receptor antagonists as potential procognitive agents. Pharmazie. 2006 Mar;61(3):179-82.@@Garduno-Torres B, Arias-Montano JA: Homologous down-regulation of histamine H3 receptors in rat striatal slices. Synapse. 2006 Aug;60(2):165-71.@@Minick DJ, Copley RC, Szewczyk JR, Rutkowske RD, Miller LA: An investigation of the absolute configuration of the potent histamine H3 receptor antagonist GT-2331 using vibrational circular dichroism. Chirality. 2007 Sep;19(9):731-40.@@Arrang JM: [The histamine H3 receptor: a new target for the treatment of arousal and cognitive disorders]. Ann Pharm Fr. 2007 Jul;65(4):275-84. |
| Groups | Approved; Investigational |
| Direct Classification | 2-arylethylamines |
| SMILES | NCCC1=CNC=N1 |
| Pathways | |
| PharmGKB | PA449880 |
| ChEMBL | CHEMBL90 |
