| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30064288 | HIV | ENSG00000124523.17 | protein_coding | SIRT5 | No | No | 23408 | Q9NXA8 |
| TVIS30017750 | HIV | ENSG00000124523.17 | protein_coding | SIRT5 | No | No | 23408 | Q9NXA8 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SIRT5 |
|---|---|
| DrugBank ID | DB04786 |
| Drug Name | Suramin |
| Target ID | BE0003362 |
| UniProt ID | Q9NXA8 |
| Regulation Type | inhibitor |
| PubMed IDs | 17355872 |
| Citations | Schuetz A, Min J, Antoshenko T, Wang CL, Allali-Hassani A, Dong A, Loppnau P, Vedadi M, Bochkarev A, Sternglanz R, Plotnikov AN: Structural basis of inhibition of the human NAD+-dependent deacetylase SIRT5 by suramin. Structure. 2007 Mar;15(3):377-89. |
| Groups | Investigational |
| Direct Classification | Benzanilides |
| SMILES | CC1=C(NC(=O)C2=CC(NC(=O)NC3=CC=CC(=C3)C(=O)NC3=C(C)C=CC(=C3)C(=O)NC3=C4C(C=C(C=C4S(O)(=O)=O)S(O)(=O)=O)=C(C=C3)S(O)(=O)=O)=CC=C2)C=C(C=C1)C(=O)NC1=C2C(C=C(C=C2S(O)(=O)=O)S(O)(=O)=O)=C(C=C1)S(O)(=O)=O |
| Pathways | |
| PharmGKB | PA10292 |
| ChEMBL | CHEMBL265502 |
