| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30077620 | HIV | ENSG00000100346.18 | protein_coding | CACNA1I | No | No | 8911 | Q9P0X4 |
| TVIS20021084 | HPV | ENSG00000100346.18 | protein_coding | CACNA1I | No | No | 8911 | Q9P0X4 |
| TVIS44018379 | HTLV-1 | ENSG00000100346.18 | protein_coding | CACNA1I | No | No | 8911 | Q9P0X4 |
| TVIS44021514 | HTLV-1 | ENSG00000100346.18 | protein_coding | CACNA1I | No | No | 8911 | Q9P0X4 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CACNA1I |
|---|---|
| DrugBank ID | DB01118 |
| Drug Name | Amiodarone |
| Target ID | BE0000012 |
| UniProt ID | Q9P0X4 |
| Regulation Type | inhibitor |
| PubMed IDs | 1281221; 20221978; 7532747 |
| Citations | Cohen CJ, Spires S, Van Skiver D: Block of T-type Ca channels in guinea pig atrial cells by antiarrhythmic agents and Ca channel antagonists. J Gen Physiol. 1992 Oct;100(4):703-28.@@Lewalter T, Pittrow D, Goette A, Kirch W, Hohnloser S: [Clinical pharmacology and electrophysiological properties of dronedarone]. Dtsch Med Wochenschr. 2010 Mar;135 Suppl 2:S43-7. doi: 10.1055/s-0030-1249208. Epub 2010 Mar 10.@@Lubic SP, Nguyen KP, Dave B, Giacomini JC: Antiarrhythmic agent amiodarone possesses calcium channel blocker properties. J Cardiovasc Pharmacol. 1994 Nov;24(5):707-14. doi: 10.1097/00005344-199424050-00004. |
| Groups | Approved; Investigational |
| Direct Classification | Aryl-phenylketones |
| SMILES | CCCCC1=C(C(=O)C2=CC(I)=C(OCCN(CC)CC)C(I)=C2)C2=C(O1)C=CC=C2 |
| Pathways | Amiodarone Action Pathway |
| PharmGKB | PA448383 |
| ChEMBL | CHEMBL633 |
