| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30018545 | HIV | ENSG00000086205.18 | protein_coding | FOLH1 | Yes | No | 2346 | Q04609 |
| TVIS20065535 | HPV | ENSG00000086205.18 | protein_coding | FOLH1 | Yes | No | 2346 | Q04609 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | FOLH1 |
|---|---|
| DrugBank ID | DB17851 |
| Drug Name | Flotufolastat F-18 |
| Target ID | BE0000568 |
| UniProt ID | Q04609 |
| Regulation Type | binder |
| PubMed IDs | 35393348; 34992154 |
| Citations | Kroenke M, Schweiger L, Horn T, Haller B, Schwamborn K, Wurzer A, Maurer T, Wester HJ, Eiber M, Rauscher I: Validation of (18)F-rhPSMA-7 and (18)F-rhPSMA-7.3 PET Imaging Results with Histopathology from Salvage Surgery in Patients with Biochemical Recurrence of Prostate Cancer. J Nucl Med. 2022 Dec;63(12):1809-1814. doi: 10.2967/jnumed.121.263707. Epub 2022 Apr 7.@@Langbein T, Wang H, Rauscher I, Kroenke M, Knorr K, Wurzer A, Schwamborn K, Maurer T, Horn T, Haller B, Wester HJ, Eiber M: Utility of (18)F-rhPSMA-7.3 PET for Imaging of Primary Prostate Cancer and Preoperative Efficacy in N-Staging of Unfavorable Intermediate- to Very High-Risk Patients Validated by Histopathology. J Nucl Med. 2022 Sep;63(9):1334-1342. doi: 10.2967/jnumed.121.263440. Epub 2022 Jan 6. |
| Groups | Approved; Investigational |
| Direct Classification | |
| SMILES | CC(C)(C)[Si]([18F])(C1=CC=C(C=C1)C(=O)NC[C@@H](NC(=O)CC[C@H](N1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1)C(O)=O)C(=O)N[C@H](CCCCNC(=O)CCC(=O)NCCC[C@@H](NC(=O)CC[C@H](NC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O)C(O)=O)C(O)=O)C(C)(C)C |
| Pathways | |
| PharmGKB | |
| ChEMBL |
