| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30082367 | HIV | ENSG00000165025.15 | protein_coding | SYK | Yes | No | 6850 | P43405 |
| TVIS30083917 | HIV | ENSG00000165025.15 | protein_coding | SYK | Yes | No | 6850 | P43405 |
| TVIS30088546 | HIV | ENSG00000165025.15 | protein_coding | SYK | Yes | No | 6850 | P43405 |
| TVIS20028144 | HPV | ENSG00000165025.15 | protein_coding | SYK | Yes | No | 6850 | P43405 |
| TVIS20069786 | HPV | ENSG00000165025.15 | protein_coding | SYK | Yes | No | 6850 | P43405 |
| TVIS20063474 | HPV | ENSG00000165025.15 | protein_coding | SYK | Yes | No | 6850 | P43405 |
| TVIS20063725 | HPV | ENSG00000165025.15 | protein_coding | SYK | Yes | No | 6850 | P43405 |
| TVIS20064042 | HPV | ENSG00000165025.15 | protein_coding | SYK | Yes | No | 6850 | P43405 |
| TVIS20063675 | HPV | ENSG00000165025.15 | protein_coding | SYK | Yes | No | 6850 | P43405 |
| TVIS44026298 | HTLV-1 | ENSG00000165025.15 | protein_coding | SYK | Yes | No | 6850 | P43405 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SYK |
|---|---|
| DrugBank ID | DB12121 |
| Drug Name | Entospletinib |
| Target ID | BE0001316 |
| UniProt ID | P43405 |
| Regulation Type | inhibitor |
| PubMed IDs | 33689480 |
| Citations | Zheng TJ, Lofurno ER, Melrose AR, Lakshmanan HHS, Pang J, Phillips KG, Fallon ME, Kohs TCL, Ngo ATP, Shatzel JJ, Hinds MT, McCarty OJT, Aslan JE: Assessment of the effects of Syk and BTK inhibitors on GPVI-mediated platelet signaling and function. Am J Physiol Cell Physiol. 2021 May 1;320(5):C902-C915. doi: 10.1152/ajpcell.00296.2020. Epub 2021 Mar 10. |
| Groups | Investigational |
| Direct Classification | Phenylmorpholines |
| SMILES | C1CN(CCO1)C1=CC=C(NC2=NC(=CN3C=CN=C23)C2=CC3=C(C=NN3)C=C2)C=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL3265032 |
