| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20031236 | HPV | ENSG00000157764.14 | protein_coding | BRAF | Yes | No | 673 | P15056 |
| TVIS20062319 | HPV | ENSG00000157764.14 | protein_coding | BRAF | Yes | No | 673 | P15056 |
| TVIS44029013 | HTLV-1 | ENSG00000157764.14 | protein_coding | BRAF | Yes | No | 673 | P15056 |
| TVIS44025844 | HTLV-1 | ENSG00000157764.14 | protein_coding | BRAF | Yes | No | 673 | P15056 |
| TVIS44045695 | HTLV-1 | ENSG00000157764.14 | protein_coding | BRAF | Yes | No | 673 | P15056 |
| TVIS44045694 | HTLV-1 | ENSG00000157764.14 | protein_coding | BRAF | Yes | No | 673 | P15056 |
| TVIS44039660 | HTLV-1 | ENSG00000157764.14 | protein_coding | BRAF | Yes | No | 673 | P15056 |
| TVIS44039659 | HTLV-1 | ENSG00000157764.14 | protein_coding | BRAF | Yes | No | 673 | P15056 |
| TVIS44039369 | HTLV-1 | ENSG00000157764.14 | protein_coding | BRAF | Yes | No | 673 | P15056 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | BRAF |
|---|---|
| DrugBank ID | DB08912 |
| Drug Name | Dabrafenib |
| Target ID | BE0000634 |
| UniProt ID | P15056 |
| Regulation Type | inhibitor |
| PubMed IDs | 23621583 |
| Citations | Gibney GT, Zager JS: Clinical development of dabrafenib in BRAF mutant melanoma and other malignancies. Expert Opin Drug Metab Toxicol. 2013 Jul;9(7):893-9. doi: 10.1517/17425255.2013.794220. Epub 2013 Apr 29. |
| Groups | Approved; Investigational |
| Direct Classification | Sulfanilides |
| SMILES | CC(C)(C)C1=NC(=C(S1)C1=NC(N)=NC=C1)C1=C(F)C(NS(=O)(=O)C2=C(F)C=CC=C2F)=CC=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL2028663 |
