| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS46000915 | BKPyv | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
| TVIS42000824 | EBV | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
| TVIS42001072 | EBV | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
| TVIS10017832 | HBV | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
| TVIS10037856 | HBV | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
| TVIS10034700 | HBV | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
| TVIS10031805 | HBV | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
| TVIS10033366 | HBV | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
| TVIS10044784 | HBV | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
| TVIS10044785 | HBV | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CFTR |
|---|---|
| DrugBank ID | DB04941 |
| Drug Name | Crofelemer |
| Target ID | BE0001195 |
| UniProt ID | P13569 |
| Regulation Type | antagonist |
| PubMed IDs | 19808995 |
| Citations | Tradtrantip L, Namkung W, Verkman AS: Crofelemer, an antisecretory antidiarrheal proanthocyanidin oligomer extracted from Croton lechleri, targets two distinct intestinal chloride channels. Mol Pharmacol. 2010 Jan;77(1):69-78. doi: 10.1124/mol.109.061051. Epub 2009 Oct 6. |
| Groups | Approved |
| Direct Classification | |
| SMILES | |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL2108184 |
