| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30047920 | HIV | ENSG00000130164.16 | protein_coding | LDLR | No | No | 3949 | P01130 |
| TVIS30047921 | HIV | ENSG00000130164.16 | protein_coding | LDLR | No | No | 3949 | P01130 |
| TVIS30047922 | HIV | ENSG00000130164.16 | protein_coding | LDLR | No | No | 3949 | P01130 |
| TVIS20054125 | HPV | ENSG00000130164.16 | protein_coding | LDLR | No | No | 3949 | P01130 |
| TVIS44042542 | HTLV-1 | ENSG00000130164.16 | protein_coding | LDLR | No | No | 3949 | P01130 |
| TVIS44051493 | HTLV-1 | ENSG00000130164.16 | protein_coding | LDLR | No | No | 3949 | P01130 |
| TVIS44051494 | HTLV-1 | ENSG00000130164.16 | protein_coding | LDLR | No | No | 3949 | P01130 |
| TVIS44051495 | HTLV-1 | ENSG00000130164.16 | protein_coding | LDLR | No | No | 3949 | P01130 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | LDLR |
|---|---|
| DrugBank ID | DB00707 |
| Drug Name | Porfimer sodium |
| Target ID | BE0000499 |
| UniProt ID | P01130 |
| Regulation Type | other/unknown |
| PubMed IDs | 1531856; 7661580; 7994588; 2945739; 1450993 |
| Citations | Korbelik M: Low density lipoprotein receptor pathway in the delivery of Photofrin: how much is it relevant for selective accumulation of the photosensitizer in tumors? J Photochem Photobiol B. 1992 Jan;12(1):107-9.@@Tsukagoshi S: [Porfimer sodium (Photofrin-II)]. Gan To Kagaku Ryoho. 1995 Aug;22(9):1271-8.@@Maziere JC, Mora L, Biade S, Maziere C, Santus R: [Potentiation of the photocytotoxic effect of photofrin II: synergistic action of verapamil and lovastatin]. Bull Acad Natl Med. 1994 Jun;178(6):1177-88; discussion 1188-9.@@Candide C, Morliere P, Maziere JC, Goldstein S, Santus R, Dubertret L, Reyftmann JP, Polonovski J: In vitro interaction of the photoactive anticancer porphyrin derivative photofrin II with low density lipoprotein, and its delivery to cultured human fibroblasts. FEBS Lett. 1986 Oct 20;207(1):133-8.@@Maziere JC, Morliere P, Biade S, Santus R: [Antitumor photochemotherapy: biochemical bases, therapeutic uses and perspectives]. C R Seances Soc Biol Fil. 1992;186(1-2):88-106. |
| Groups | Approved; Investigational |
| Direct Classification | |
| SMILES | |
| Pathways | |
| PharmGKB | PA164752658 |
| ChEMBL |
