SNP Detail Info-rs10753308

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A==0309 (9279/29944,GnomAD)
A==0319 (9311/29118,TOPMED)
A==0380 (1903/5008,1000G)
A==0328 (1265/3854,ALSPAC)
A==0341 (1264/3708,TWINSUK)

Position: chr1:34441547 (GRCh38.p7) (1p34.3)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 20 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.34441547A>G
GRCh37.p13 chr 1	NC_000001.10:g.34907148A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.301	G=0.699
1000Genomes	American	Sub	694	A=0.440	G=0.560
1000Genomes	East Asian	Sub	1008	A=0.402	G=0.598
1000Genomes	Europe	Sub	1006	A=0.306	G=0.694
1000Genomes	Global	Study-wide	5008	A=0.380	G=0.620
1000Genomes	South Asian	Sub	978	A=0.500	G=0.500
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.328	G=0.672
The Genome Aggregation Database	African	Sub	8714	A=0.311	G=0.689
The Genome Aggregation Database	American	Sub	836	A=0.420	G=0.580
The Genome Aggregation Database	East Asian	Sub	1614	A=0.388	G=0.612
The Genome Aggregation Database	Europe	Sub	18478	A=0.298	G=0.701
The Genome Aggregation Database	Global	Study-wide	29944	A=0.309	G=0.690
The Genome Aggregation Database	Other	Sub	302	A=0.240	G=0.760
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.319	G=0.680
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.341	G=0.659

PMID	Title	Author	Journal
17158188	Novel genes identified in a high-density genome wide association study for nicotine dependence.	Bierut LJ	Hum Mol Genet

SNP ID	p-value	Traits	Study
rs10753308	0.000761	nicotine dependence	17158188

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr1	34863862	34864239	E070	-42909
chr1	34872086	34872290	E070	-34858
chr1	34872360	34872435	E070	-34713
chr1	34872535	34872665	E070	-34483
chr1	34872885	34872996	E070	-34152
chr1	34945497	34945620	E070	38349
chr1	34945290	34945363	E073	38142
chr1	34890758	34890928	E081	-16220
chr1	34945290	34945363	E081	38142
chr1	34945497	34945620	E081	38349
chr1	34948168	34948897	E081	41020
chr1	34863862	34864239	E082	-42909
chr1	34864421	34864504	E082	-42644
chr1	34864602	34864736	E082	-42412
chr1	34872086	34872290	E082	-34858
chr1	34872360	34872435	E082	-34713
chr1	34872535	34872665	E082	-34483
chr1	34872885	34872996	E082	-34152
chr1	34945290	34945363	E082	38142
chr1	34945497	34945620	E082	38349

rs10753308