ACSL3	acyl-CoA synthetase long-chain family member 3	2181	2	2q36	yes		prostate			E	Dom	T	ETV1			"PRO2194	2181	ACSL3	ENSG00000123983	O95573	FACL3	ACS3"
AKT1	v-akt murine thymoma viral oncogene homolog 1	207	14	14q32.32	yes		"breast	 colorectal	 ovarian	 NSCLC"			E	Dom	Mis				"AKT1_NEW	P31749	RAC-ALPHA	RAC	PRKBA	PKB-ALPHA	PKB	MGC99656	AKT	ENSG00000142208	207"
ALDH2	aldehyde dehydrogenase 2 family (mitochondrial)	217	12	12q24.2	yes		leiomyoma			M	Dom	T	HMGA2			"ALDHI	ALDH2	217	ENSG00000111275	ALDH-E2	P05091	MGC1806	ALDM"
ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	471	2	2q35	yes		ALCL			L	Dom	T	ALK			"IMPCHASE	P31939	471	ATIC	ENSG00000138363	AICARFT	PURH"
CALR	calreticulin	811	19	p13.3-p13.2	yes		"MPN	 MDS"			L	Dom	"F	 Mis"				"ENSG00000179218	811	CALR	P27797	SSA	RO	FLJ26680	cC1qR"
CANT1	calcium activated nucleotidase 1	124583	17	17q25	yes		prostate			E	Dom	T	ETV4			"ENSG00000171302	124583	CANT1	Q8WVQ1	SHAPY	SCAN-1"
CDX2	caudal type homeo box transcription factor 2	1045	13	13q12.3	yes		AML			L	Dom	T	ETV6			"CDX3	1045	CDX2	ENSG00000165556	Q99626"
CNOT3	CCR4-NOT transcription complex subunit 3	4849	19	19q13.4	yes		T-ALL			L	Rec	"Mis	 N	 F"				"KIAA0691	4849	CNOT3	ENSG00000088038	O75175	NOT3H	NOT3	LENG2"
CREBBP	CREB binding protein (CBP)	1387	16	16p13.3	yes		"ALL	 AML	 DLBCL	 B-NHL"			L	Dom/Rec	"T	 N	 F	 Mis	 O"	"MLL	 MORF	 RUNXBP2"	yes	Rubinstein-Taybi syndrome	"CBP	1387	CREBBP	ENSG00000005339	RSTS	RTS"
CTNNB1	"catenin (cadherin-associated protein)	 beta 1"	1499	3	3p22-p21.3	yes		"colorectal	 ovarian	  hepatoblastoma	 pleomorphic salivary gland adenoma	 other tumour types"			"E	 M	 O"	Dom	"Mis	 O	 T"	PLAG1			"CTNNB	P35222	CTNNB1	1499	ENSG00000168036"
DDX6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	1656	11	11q23.3	yes		B-NHL			L	Dom	T	IGH@			"P54	DDX6	1656	ENSG00000110367	HLR2	P26196	RCK	FLJ36338"
DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	1788	2	2p23	yes		AML			L	Rec	"Mis	 F	 N	 S"				"Q9Y6K1	DNMT3A	1788	ENSG00000119772	DNMT3A2	M_HsaIIIA"
EIF3E	"eukaryotic translation initiation factor 3	 subunit E"	3646	8	8q22-q23	yes		colorectal			E	Dom	T	RSPO3			"eIF3-p46	EIF3S6	3646	ENSG00000104408	EIF3S6	eIF3e	EIF3-P48	INT6"
EIF4A2	"eukaryotic translation initiation factor 4A	 isoform 2"	1974	3	3q27.3	yes		NHL			L	Dom	T	BCL6			"DDX2B	1974	EIF4A2	ENSG00000156976	EIF4F	BM-010	EIF4A"
EP300	300 kd E1A-Binding protein gene	2033	22	22q13	yes		"colorectal	 breast	 pancreatic	 AML	 ALL	 DLBCL"			"L	 E"	Rec	"T	  N	 F	 Mis	 O"	"MLL	 RUNXBP2"			"ENSG00000100393	2033	EP300	RP1-85F18_1	p300"
EXT1	multiple exostoses type 1 gene	2131	8	8q24.11-q24.13		yes		"exostoses	 osteosarcoma"	multiple exostoses type 1	M	Rec	"Mis	 N	 F	 S"				"ttv	EXT1	2131	ENSG00000182197	EXT	Q16394"
EXT2	multiple exostoses type 2 gene	2132	11	11p12-p11		yes		"exostoses	 osteosarcoma"	multiple exostoses type 2	M	Rec	"Mis	 N	 F	 S"				"Q93063	ENSG00000151348	2132	EXT2	SOTV"
FBXW7	"F-box and WD-40 domain protein 7 (archipelago homolog	 Drosophila)"	55294	4	4q31.3	yes		"colorectal	 endometrial	 T-ALL"			"E	 L"	Rec	"Mis	 N	 D	 F"				"AGO	DKFZp686F23254	55294	FBXW7	ENSG00000109670	FLJ11071	SEL-10	CDC4	FBXW6	SEL10	FBW7	FBX30"
FH	fumarate hydratase	2271	1	1q42.1		yes		"leiomyomatosis	 renal"	hereditary leiomyomatosis and renal cell cancer	"E	 M"	Rec	"Mis	 N	 F"				"HLRCC	FH	2271	ENSG00000091483	MCUL1	MCL	LRCC	P07954"
FHIT	fragile histidine triad gene	2272	3	3p14.2	yes		pleomorphic salivary gland adenoma			E	Dom	T	HMGA2			"FHIT	P49789	FRA3B	AP3Aase	ENSG00000189283	2272"
GMPS	guanine monphosphate synthetase	8833	3	3q24	yes		AML			L	Dom	T	MLL			"ENSG00000163655	GMPS	8833"
GNA11	"guanine nucleotide binding protein (G protein)	 alpha 11 (Gq class)"	2767	19	19p13.3	yes		uveal melanoma			E	Dom	Mis				"GNA-11	GNA11	2767	ENSG00000088256"
GNAQ	"guanine nucleotide binding protein (G protein)	 q polypeptide"	2776	9	9q21	yes		uveal melanoma			E	Dom	Mis				"P50148	2776	GNAQ	ENSG00000156052	G-ALPHA-q	RP11-494N1_1	GAQ"
GNAS	"guanine nucleotide binding protein (G protein)	 alpha stimulating activity polypeptide 1"	2778	20	20q13.2	yes		pituitary adenoma			E	Dom	Mis		yes	"McCune-Albright syndrome; pseudohypoparathyroidism	 type IA"	"RP4-543J19_4	2778	GNAS	ENSG00000087460	NESP55	NESP	GSP	POH	GNASXL	GNAS1	C20orf45	dJ309F20_1_1	SCG6	GPSA	Gnas	dJ806M20_3_3	XL2	MGC33735	XL	PHP1A	GSA	AHO	XLalphas	PHP1B"
GPC3	glypican 3	2719	X	Xq26.1		yes		Wilms tumour	Simpson-Golabi-Behmel syndrome	O	Rec/X	"T	 D	 Mis	 N	 F	 S"				"OCI-5	GPC3	2719	ENSG00000147257	SGBS	SGB	DGSX	SDYS	P51654	AC002420_1	SGBS1"
GPHN	gephyrin (GPH)	10243	14	14q24	yes		AL			L	Dom	T	MLL			"ENSG00000171723	10243	GPHN"
IDH1	"isocitrate dehydrogenase 1 (NADP+)	 soluble"	3417	2	2q33.3	yes		glioblastoma			O	Dom	Mis				"IDP	3417	IDH1	ENSG00000138413	IDH	PICD	O75874"
IDH2	"socitrate dehydrogenase 2 (NADP+)	 mitochondrial"	3418	15	15q26.1	yes		glioblastoma			M	Dom	M				"P48735	ICD-M	IDH2	3418	ENSG00000182054	IDHM	mNADP-IDH	IDH	IDP"
MED12	mediator complex subunit 12	9968	X	Xq13	yes		uterine leiomyoma			M	Dom	"M	 S"		Yes	Opitz-Kaveggia Syndrome	"MED12_ENST00000374080	Q93074	KIAA0192	TRAP230	TNRC11	OKS	HOPA	FGS1	CAGH45	ARC240	9968"
NCOA1	nuclear receptor coactivator 1	8648	2	2p23	yes		alveolar rhabdomyosarcoma			M	Dom	T	PAX3			"RIP160	NCOA1	8648	ENSG00000084676	NCoA-1	SRC1	MGC129719	MGC129720	F-SRC-1"
NCOA2	nuclear receptor coactivator 2 (TIF2)	10499	8	8q13.1	yes		"AML	 chondrosarcoma"			L	Dom	T	"RUNXBP2	 HEY1"			"TIF2	NCOA2	10499	ENSG00000140396	NCoA-2	MGC138808"
NT5C2	"5'-nucleotidase	 cytosolic II"	22978	10	10q24.32	yes		relapse ALL			L		Mis				"ENSG00000076685	22978	NT5C2	P49902	PNT5	NT5B	GMP	cN-II"
NUP214	nucleoporin 214kDa (CAN)	8021	9	9q34.1	yes		"AML	 T-ALL"			L	Dom	T	"DEK	 SET	 ABL1"			"ENSG00000126883	NUP214	8021	MGC104525	D9S46E	RP11-544A12_7	N214	CAIN	P35658	CAN"
OMD	osteomodulin	4958	9	9q22.31	yes		aneurysmal bone cyst			M	Dom	T	USP6			"osteoadherin	OMD	4958	ENSG00000127083	Q99983	SLRR2C"
PAFAH1B2	"platelet-activating factor acetylhydrolase	 isoform Ib	 beta subunit 30kDa"	5049	11	11q23	yes		MLCLS			L	Dom	T	IGH@			"P68402	5049	PAFAH1B2	ENSG00000168092"
PIK3CA	"phosphoinositide-3-kinase	 catalytic	 alpha polypeptide"	5290	3	3q26.3	yes		"colorectal	 gastric	 glioblastoma	 breast"			"E	 O"	Dom	Mis				"MGC142161	5290	PIK3CA	ENSG00000121879	P42336	MGC142163	p110-alpha	PI3K"
PIK3R1	"phosphoinositide-3-kinase	 regulatory subunit 1 (alpha)"	5295	5	5q13.1	yes		"glioblastoma	 ovarian	 colorectal"			"E	 O"	Rec	"Mis	 F	 O"				"P27986	p85-ALPHA	GRB1	5295	PIK3R1	ENSG00000145675"
PLCG1	"phospholipase C	 gamma 1"	5335	20	20q12-q13.1	yes		angiosarcoma			E	Dom	Mis				"PLC1	PLCG1	5335	ENSG00000124181	PLC-II	Plcg1	PLCgamma1	PLC148"
PPARG	"peroxisome proliferative activated receptor	 gamma"	5468	3	3p25	yes		follicular thyroid			E	Dom	T	PAX8	yes	"Insulin resistance ; lipodystrophy	 familial partial L;diabetes mellitus	 insulin-resistantI	 with acanthosis nigricans and hypertension"	"PPARG1	HUMPPARG	PPARG	5468	ENSG00000132170	PPARG2	NR1C3"
PPP2R1A	"protein phosphatase 2	 regulatory subunit A	 alpha"	5518	19	19q13.41	yes		clear cell ovarian carcinoma			E	Dom?	Mis				"PR65A	MGC786	PPP2R1A	5518	ENSG00000105568	P30153"
PRKAR1A	"protein kinase	 cAMP-dependent	 regulatory	 type I	 alpha (tissue specific extinguisher 1)"	5573	17	17q23-q24	yes	yes	papillary thyroid	"myxoma	 endocrine	 papillary thyroid"	Carney complex	"E	 M"	"Dom	 Rec"	"T	 Mis	 N	 F	 S"	RET			"CAR	DKFZp779L0468	PPNAD1	5573	PRKAR1A	ENSG00000108946	PRKAR1	P10644	CNC1	PKR1	MGC17251	TSE1	CNC"
PTEN	phosphatase and tensin homolog gene	5728	10	10q23.3	yes	yes	"glioma	 prostate	 endometrial"	"harmartoma	 glioma	 prostate	 endometrial"	"Cowden syndrome	 Bannayan-Riley-Ruvalcaba syndrome"	"L	 E	 M	 O"	Rec	"D	 Mis	 N	 F	 S"				"MMAC1	P60484	MHAM	5728	PTEN	MGC11227	PTEN1	BZS	ENSG00000171862"
RPL10	ribosomal protein L10	6134	X	Xq28	yes		T-ALL			L	Dom	Mis				"XX-FW83563B9_1	6134	RPL10	ENSG00000147403	FLJ27072	DXS648	DXS648E	DKFZp686J1851	P27635	QM	FLJ23544"
RPL22	ribosomal protein L22 (EAP)	6146	1	1p36.31	yes		"AML	 CML"			L	Dom	T	RUNX1			"EAP	RPL22	6146"
RPL5	ribososomal protein L5	6125	1	1p22.1	yes		T-ALL			L	Dom	"Mis	 N	 F"		yes	Diamond-Blackfan anaemia	"RPL5	6125	MSTP030	P46777	MGC117339	ENSG00000122406"
RPN1	ribophorin I	6184	3	3q21.3-q25.2	yes		AML			L	Dom	T	EVI1			"OST1	6184	RPN1	ENSG00000163902	P04843"
SDC4	syndecan 4	6385	20	20q12	yes		NSCLC			E	Dom	T	ROS1			"ENSG00000124145	6385	SDC4	P31431	SYND4	MGC22217"
SDHB	"succinate dehydrogenase complex	 subunit B	 iron sulfur (Ip)"	6390	1	1p36.1-p35		yes		"paraganglioma	 pheochromocytoma"	familial paraganglioma	O	Rec	"Mis	 N	 F"				"PGL4	SDH1	SDHB	6390	ENSG00000117118	SDHIP	SDH	IP"
SDHC	"succinate dehydrogenase complex	 subunit C	 integral membrane protein	 15kDa"	6391	1	1q21		yes		"paraganglioma	 pheochromocytoma"	familial paraganglioma	O	Rec	"Mis	 N	 F"				"CYBL	SDH3	CYB560	SDHC	6391	ENSG00000143252	PGL3	QPS1"
SDHD	"succinate dehydrogenase complex	 subunit D	 integral membrane protein"	6392	11	11q23		yes		"paraganglioma	 pheochromocytoma"	familial paraganglioma	O	Rec	"Mis	 N	 F	 S"				"PGL1	SDHD	6392	ENSG00000204370	PGL	SDH4	CBT1	O14521"
STK11	serine/threonine kinase 11 gene (LKB1)	6794	19	19p13.3	yes	yes	"NSCLC	 pancreatic"	"jejunal hamartoma	 ovarian	 testicular	 pancreatic"	Peutz-Jeghers syndrome	"E	 M	 O"	Rec	"D	 Mis	 N	 F	 S"				"LKB1	6794	STK11	ENSG00000118046	Q15831	PJS"
TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	79718	3	3q26.32	yes		splenic marginal zone lymphoma			L		"F	 Mis"				"C21	79718	TBL1XR1	TBLR1	IRA1	FLJ12894	DC42"
TP53	tumor protein p53	7157	17	17p13	yes	yes	"breast	 colorectal	 lung	 sarcoma	 adrenocortical	 glioma	 Spitzoid tumour	 multiple other tumour types"	"breast	 sarcoma	 adrenocortical carcinoma	 glioma	 multiple other tumour types"	Li-Fraumeni syndrome	"L	 E	 M	 O"	Rec	"Mis	 N	 F	 T"	NTRK1			"TRP53	LFS1	7157	TP53	ENSG00000141510	P04637	P53	p53"
TPR	translocated promoter region	7175	1	1q25	yes		"papillary thyroid	 NSCLC"			E	Dom	T	"NTRK1	 ALK"			"P12270	TPR	7175"
WWTR1	WW domain containing transcription regulator 1	25937	3	3q23-q24	yes		epithelioid haemangioendothelioma			M	Dom	T	CAMTA1			"ENSG00000018408	25937	WWTR1	Q9GZV5	DKFZP586I1419"
XPO1	"exportin 1 (CRM1 homolog	 yeast)"	7514	2	2p15	yes		CLL			L	Dom	Mis				"DKFZp686B1823	7514	XPO1	ENSG00000082898	O14980	CRM1"