Cancer Cell Metabolism Gene Database

  Cancer Cell Metabolism Gene DB

Home

Search

Download

 Statistics

Help

About Us
Bioinformatics and Systems Medicine Laboratory Bioinformatics and Systems Medicine Laboratory
Cross referenced IDs for 5295
* We obtained these cross-references from Uniprot database. It covers 150 different DBs, 18 categories. http://www.uniprot.org/help/cross_references_section
DB CategoryDB NameDB's ID and Url link
Genome annotation databasesEnsembl ENST00000320694; ENSP00000323512; ENSG00000145675. [P27986-3]
Genome annotation databasesEnsembl ENST00000336483; ENSP00000338554; ENSG00000145675. [P27986-2]
Genome annotation databasesEnsembl ENST00000521381; ENSP00000428056; ENSG00000145675. [P27986-1]
Genome annotation databasesEnsembl ENST00000521657; ENSP00000429277; ENSG00000145675. [P27986-1]
Genome annotation databasesEnsembl ENST00000523872; ENSP00000430098; ENSG00000145675. [P27986-5]
Genome annotation databasesGeneID 5295; -.
Genome annotation databasesKEGG hsa:5295; -.
Genome annotation databasesUCSC uc003jva.3; human. [P27986-1]
Genome annotation databasesUCSC uc003jvc.3; human. [P27986-3]
Genome annotation databasesUCSC uc003jvd.3; human. [P27986-2]
Sequence databasesCCDS CCDS3993.1; -. [P27986-1]
Sequence databasesCCDS CCDS3994.1; -. [P27986-3]
Sequence databasesCCDS CCDS3995.1; -. [P27986-2]
Sequence databasesCCDS CCDS56374.1; -. [P27986-5]
Sequence databasesEMBL M61906; -; NOT_ANNOTATED_CDS; mRNA.
Sequence databasesEMBL U49349; AAB04140.1; -; mRNA.
Sequence databasesEMBL AF279367; AAO15359.1; -; mRNA.
Sequence databasesEMBL AK094785; BAG52931.1; -; mRNA.
Sequence databasesEMBL AK223613; BAD97333.1; -; mRNA.
Sequence databasesEMBL AC016564; -; NOT_ANNOTATED_CDS; Genomic_DNA.
Sequence databasesEMBL AC104120; -; NOT_ANNOTATED_CDS; Genomic_DNA.
Sequence databasesEMBL CH471137; EAW51312.1; -; Genomic_DNA.
Sequence databasesEMBL CH471137; EAW51313.1; -; Genomic_DNA.
Sequence databasesEMBL BC030815; AAH30815.1; -; mRNA.
Sequence databasesEMBL BC094795; AAH94795.1; -; mRNA.
Sequence databasesPIR A38748; A38748.
Sequence databasesRefSeq NP_001229395.1; NM_001242466.1. [P27986-5]
Sequence databasesRefSeq NP_852556.2; NM_181504.3. [P27986-2]
Sequence databasesRefSeq NP_852664.1; NM_181523.2. [P27986-1]
Sequence databasesRefSeq NP_852665.1; NM_181524.1. [P27986-3]
Sequence databasesRefSeq XP_005248599.1; XM_005248542.1. [P27986-1]
Sequence databasesUniGene Hs.132225; -.
Sequence databasesUniGene Hs.604502; -.
Sequence databasesUniGene Hs.734132; -.
Polymorphism databasesDMDM 118572681; -.
Gene expression databasesBgee P27986; -.
Gene expression databasesCleanEx HS_PIK3R1; -.
Gene expression databasesExpressionAtlas P27986; baseline and differential.
Gene expression databasesGenevestigator P27986; -.
OntologiesGO GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB.
OntologiesGO GO:0005911; C:cell-cell junction; IEA:Ensembl.
OntologiesGO GO:0005829; C:cytosol; TAS:Reactome.
OntologiesGO GO:0016020; C:membrane; IDA:UniProtKB.
OntologiesGO GO:0005942; C:phosphatidylinositol 3-kinase complex; ISS:BHF-UCL.
OntologiesGO GO:0005886; C:plasma membrane; TAS:Reactome.
OntologiesGO GO:0043125; F:ErbB-3 class receptor binding; IDA:UniProtKB.
OntologiesGO GO:0043559; F:insulin binding; IDA:UniProtKB.
OntologiesGO GO:0005158; F:insulin receptor binding; IPI:UniProtKB.
OntologiesGO GO:0043560; F:insulin receptor substrate binding; ISS:BHF-UCL.
OntologiesGO GO:0005159; F:insulin-like growth factor receptor binding; IPI:UniProtKB.
OntologiesGO GO:0005168; F:neurotrophin TRKA receptor binding; IPI:UniProtKB.
OntologiesGO GO:0043548; F:phosphatidylinositol 3-kinase binding; ISS:BHF-UCL.
OntologiesGO GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; ISS:UniProtKB.
OntologiesGO GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
OntologiesGO GO:0005068; F:transmembrane receptor protein tyrosine kinase adaptor activity; ISS:BHF-UCL.
OntologiesGO GO:0030183; P:B cell differentiation; IEA:Ensembl.
OntologiesGO GO:0007596; P:blood coagulation; TAS:Reactome.
OntologiesGO GO:0034644; P:cellular response to UV; IEA:Ensembl.
OntologiesGO GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
OntologiesGO GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
OntologiesGO GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0060396; P:growth hormone receptor signaling pathway; IDA:BHF-UCL.
OntologiesGO GO:0045087; P:innate immune response; TAS:Reactome.
OntologiesGO GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0048009; P:insulin-like growth factor receptor signaling pathway; IPI:UniProtKB.
OntologiesGO GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
OntologiesGO GO:0050900; P:leukocyte migration; TAS:Reactome.
OntologiesGO GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
OntologiesGO GO:0001953; P:negative regulation of cell-matrix adhesion; IEA:Ensembl.
OntologiesGO GO:0045671; P:negative regulation of osteoclast differentiation; IEA:Ensembl.
OntologiesGO GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0051531; P:NFAT protein import into nucleus; IEA:Ensembl.
OntologiesGO GO:0014065; P:phosphatidylinositol 3-kinase signaling; IDA:BHF-UCL.
OntologiesGO GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
OntologiesGO GO:0046854; P:phosphatidylinositol phosphorylation; ISS:UniProtKB.
OntologiesGO GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
OntologiesGO GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
OntologiesGO GO:0030168; P:platelet activation; TAS:Reactome.
OntologiesGO GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
OntologiesGO GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; ISS:BHF-UCL.
OntologiesGO GO:0046326; P:positive regulation of glucose import; ISS:BHF-UCL.
OntologiesGO GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
OntologiesGO GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Ensembl.
OntologiesGO GO:0006468; P:protein phosphorylation; IEA:Ensembl.
OntologiesGO GO:0043551; P:regulation of phosphatidylinositol 3-kinase activity; ISS:BHF-UCL.
OntologiesGO GO:0044281; P:small molecule metabolic process; TAS:Reactome.
OntologiesGO GO:0031295; P:T cell costimulation; TAS:Reactome.
OntologiesGO GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0016032; P:viral process; IEA:UniProtKB-KW.
Proteomic databasesMaxQB P27986; -.
Proteomic databasesPaxDb P27986; -.
Proteomic databasesPRIDE P27986; -.
Family and domain databasesGene3D 1.10.555.10; -; 1.
Family and domain databasesGene3D 3.30.505.10; -; 2.
Family and domain databasesInterPro IPR001720; PI3kinase_P85.
Family and domain databasesInterPro IPR008936; Rho_GTPase_activation_prot.
Family and domain databasesInterPro IPR000198; RhoGAP_dom.
Family and domain databasesInterPro IPR000980; SH2.
Family and domain databasesInterPro IPR011511; SH3_2.
Family and domain databasesInterPro IPR001452; SH3_domain.
Family and domain databasesPANTHER PTHR10155; PTHR10155; 1.
Family and domain databasesPfam PF00620; RhoGAP; 1.
Family and domain databasesPfam PF00017; SH2; 2.
Family and domain databasesPfam PF07653; SH3_2; 1.
Family and domain databasesPRINTS PR00678; PI3KINASEP85.
Family and domain databasesPRINTS PR00401; SH2DOMAIN.
Family and domain databasesPROSITE PS50238; RHOGAP; 1.
Family and domain databasesPROSITE PS50001; SH2; 2.
Family and domain databasesPROSITE PS50002; SH3; 1.
Family and domain databasesSMART SM00324; RhoGAP; 1.
Family and domain databasesSMART SM00252; SH2; 2.
Family and domain databasesSMART SM00326; SH3; 1.
Family and domain databasesSUPFAM SSF48350; SSF48350; 1.
Family and domain databasesSUPFAM SSF50044; SSF50044; 1.
Family and domain databasesSUPFAM SSF55550; SSF55550; 2.
PTM databasesPhosphoSite P27986; -.
Protein-protein interaction databasesBioGrid 111313; 133.
Protein-protein interaction databasesDIP DIP-119N; -.
Protein-protein interaction databasesIntAct P27986; 197.
Protein-protein interaction databasesMINT MINT-93751; -.
Protein-protein interaction databasesSTRING 9606.ENSP00000274335; -.
Enzyme and pathway databasesBioCyc MetaCyc:ENSG00000145675-MONOMER; -.
Enzyme and pathway databasesReactome REACT_111040; Signaling by SCF-KIT.
Enzyme and pathway databasesReactome REACT_115529; Interleukin-7 signaling.
Enzyme and pathway databasesReactome REACT_115852; Signaling by constitutively active EGFR.
Enzyme and pathway databasesReactome REACT_115961; PI3K events in ERBB4 signaling.
Enzyme and pathway databasesReactome REACT_116008; PI3K events in ERBB2 signaling.
Enzyme and pathway databasesReactome REACT_118700; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers.
Enzyme and pathway databasesReactome REACT_121025; Synthesis of PIPs at the plasma membrane.
Enzyme and pathway databasesReactome REACT_121141; Signaling by FGFR1 fusion mutants.
Enzyme and pathway databasesReactome REACT_121398; Signaling by FGFR mutants.
Enzyme and pathway databasesReactome REACT_12464; PI3K/AKT activation.
Enzyme and pathway databasesReactome REACT_12555; Downstream TCR signaling.
Enzyme and pathway databasesReactome REACT_12578; GAB1 signalosome.
Enzyme and pathway databasesReactome REACT_12621; Tie2 Signaling.
Enzyme and pathway databasesReactome REACT_147727; Constitutive PI3K/AKT Signaling in Cancer.
Enzyme and pathway databasesReactome REACT_147814; DAP12 signaling.
Enzyme and pathway databasesReactome REACT_160158; Role of phospholipids in phagocytosis.
Enzyme and pathway databasesReactome REACT_163769; Role of LAT2/NTAL/LAB on calcium mobilization.
Enzyme and pathway databasesReactome REACT_1695; GPVI-mediated activation cascade.
Enzyme and pathway databasesReactome REACT_17025; Downstream signal transduction.
Enzyme and pathway databasesReactome REACT_18283; G alpha (q) signalling events.
Enzyme and pathway databasesReactome REACT_18407; G alpha (12/13) signalling events.
Enzyme and pathway databasesReactome REACT_19290; G beta:gamma signalling through PI3Kgamma.
Enzyme and pathway databasesReactome REACT_19344; Costimulation by the CD28 family.
Enzyme and pathway databasesReactome REACT_19358; CD28 dependent PI3K/Akt signaling.
Enzyme and pathway databasesReactome REACT_21270; PI-3K cascade.
Enzyme and pathway databasesReactome REACT_228166; VEGFA-VEGFR2 Pathway.
Enzyme and pathway databasesReactome REACT_23787; Regulation of signaling by CBL.
Enzyme and pathway databasesReactome REACT_23832; Nephrin interactions.
Enzyme and pathway databasesReactome REACT_23837; Interleukin-3, 5 and GM-CSF signaling.
Enzyme and pathway databasesReactome REACT_23847; GP1b-IX-V activation signalling.
Enzyme and pathway databasesReactome REACT_23891; Interleukin receptor SHC signaling.
Enzyme and pathway databasesReactome REACT_75829; PIP3 activates AKT signaling.
Enzyme and pathway databasesReactome REACT_976; PI3K Cascade.
Enzyme and pathway databasesSignaLink P27986; -.
3D structure databasesPDB 1A0N; NMR; -; A=91-104.
3D structure databasesPDB 1AZG; NMR; -; A=91-104.
3D structure databasesPDB 1H9O; X-ray; 1.79 A; A=617-724.
3D structure databasesPDB 1PBW; X-ray; 2.00 A; A/B=105-319.
3D structure databasesPDB 1PHT; X-ray; 2.00 A; A=1-85.
3D structure databasesPDB 1PIC; NMR; -; A=617-724.
3D structure databasesPDB 1PKS; NMR; -; A=1-79.
3D structure databasesPDB 1PKT; NMR; -; A=1-79.
3D structure databasesPDB 2IUG; X-ray; 1.89 A; A=321-440.
3D structure databasesPDB 2IUH; X-ray; 2.00 A; A=321-440.
3D structure databasesPDB 2IUI; X-ray; 2.40 A; A/B=321-440.
3D structure databasesPDB 2RD0; X-ray; 3.05 A; B=322-600.
3D structure databasesPDB 2V1Y; X-ray; 2.40 A; B=431-600.
3D structure databasesPDB 3HHM; X-ray; 2.80 A; B=322-694.
3D structure databasesPDB 3HIZ; X-ray; 3.30 A; B=322-694.
3D structure databasesPDB 3I5R; X-ray; 1.70 A; A=1-83.
3D structure databasesPDB 3I5S; X-ray; 3.00 A; A/B/C/D=1-83.
3D structure databasesPDB 4A55; X-ray; 3.50 A; B=322-600.
3D structure databasesPDB 4JPS; X-ray; 2.20 A; B=307-593.
3D structure databasesPDB 4L1B; X-ray; 2.59 A; B=318-615.
3D structure databasesPDB 4L23; X-ray; 2.50 A; B=318-615.
3D structure databasesPDB 4L2Y; X-ray; 2.80 A; B=318-615.
3D structure databasesPDB 4OVU; X-ray; 2.96 A; B=322-600.
3D structure databasesPDB 4OVV; X-ray; 3.50 A; B=322-600.
3D structure databasesPDBsum 1A0N; -.
3D structure databasesPDBsum 1AZG; -.
3D structure databasesPDBsum 1H9O; -.
3D structure databasesPDBsum 1PBW; -.
3D structure databasesPDBsum 1PHT; -.
3D structure databasesPDBsum 1PIC; -.
3D structure databasesPDBsum 1PKS; -.
3D structure databasesPDBsum 1PKT; -.
3D structure databasesPDBsum 2IUG; -.
3D structure databasesPDBsum 2IUH; -.
3D structure databasesPDBsum 2IUI; -.
3D structure databasesPDBsum 2RD0; -.
3D structure databasesPDBsum 2V1Y; -.
3D structure databasesPDBsum 3HHM; -.
3D structure databasesPDBsum 3HIZ; -.
3D structure databasesPDBsum 3I5R; -.
3D structure databasesPDBsum 3I5S; -.
3D structure databasesPDBsum 4A55; -.
3D structure databasesPDBsum 4JPS; -.
3D structure databasesPDBsum 4L1B; -.
3D structure databasesPDBsum 4L23; -.
3D structure databasesPDBsum 4L2Y; -.
3D structure databasesPDBsum 4OVU; -.
3D structure databasesPDBsum 4OVV; -.
3D structure databasesProteinModelPortal P27986; -.
3D structure databasesSMR P27986; 3-85, 115-309, 322-724.
Protocols and materials databasesDNASU 5295; -.
Phylogenomic databaseseggNOG NOG263689; -.
Phylogenomic databasesGeneTree ENSGT00390000010431; -.
Phylogenomic databasesHOVERGEN HBG082100; -.
Phylogenomic databasesInParanoid P27986; -.
Phylogenomic databasesKO K02649; -.
Phylogenomic databasesOMA LNGYNET; -.
Phylogenomic databasesOrthoDB EOG7BP831; -.
Phylogenomic databasesPhylomeDB P27986; -.
Phylogenomic databasesTreeFam TF102033; -.
Organism-specific databasesCTD 5295; -.
Organism-specific databasesGeneCards GC05P067511; -.
Organism-specific databasesHGNC HGNC:8979; PIK3R1.
Organism-specific databasesHPA CAB004268; -.
Organism-specific databasesHPA HPA001216; -.
Organism-specific databasesMIM 171833; gene.
Organism-specific databasesMIM 269880; phenotype.
Organism-specific databasesMIM 615214; phenotype.
Organism-specific databasesneXtProt NX_P27986; -.
Organism-specific databasesOrphanet 33110; Autosomal agammaglobulinemia.
Organism-specific databasesOrphanet 3163; SHORT syndrome.
Organism-specific databasesPharmGKB PA33312; -.
ChemistryBindingDB P27986; -.
ChemistryChEMBL CHEMBL2111367; -.
ChemistryDrugBank DB01064; Isoprenaline.
OtherChiTaRS PIK3R1; human.
OtherEvolutionaryTrace P27986; -.
OtherGeneWiki PIK3R1; -.
OtherGenomeRNAi 5295; -.
OtherNextBio 20462; -.
OtherPRO PR:P27986; -.
Genome annotation databasesEnsembl ENST00000320694; ENSP00000323512; ENSG00000145675. [P27986-3]
Genome annotation databasesEnsembl ENST00000336483; ENSP00000338554; ENSG00000145675. [P27986-2]
Genome annotation databasesEnsembl ENST00000521381; ENSP00000428056; ENSG00000145675. [P27986-1]
Genome annotation databasesEnsembl ENST00000521657; ENSP00000429277; ENSG00000145675. [P27986-1]
Genome annotation databasesEnsembl ENST00000523872; ENSP00000430098; ENSG00000145675. [P27986-5]
Genome annotation databasesGeneID 5295; -.
Genome annotation databasesKEGG hsa:5295; -.
Genome annotation databasesUCSC uc003jva.3; human. [P27986-1]
Genome annotation databasesUCSC uc003jvc.3; human. [P27986-3]
Genome annotation databasesUCSC uc003jvd.3; human. [P27986-2]
Sequence databasesCCDS CCDS3993.1; -. [P27986-1]
Sequence databasesCCDS CCDS3994.1; -. [P27986-3]
Sequence databasesCCDS CCDS3995.1; -. [P27986-2]
Sequence databasesCCDS CCDS56374.1; -. [P27986-5]
Sequence databasesEMBL M61906; -; NOT_ANNOTATED_CDS; mRNA.
Sequence databasesEMBL U49349; AAB04140.1; -; mRNA.
Sequence databasesEMBL AF279367; AAO15359.1; -; mRNA.
Sequence databasesEMBL AK094785; BAG52931.1; -; mRNA.
Sequence databasesEMBL AK223613; BAD97333.1; -; mRNA.
Sequence databasesEMBL AC016564; -; NOT_ANNOTATED_CDS; Genomic_DNA.
Sequence databasesEMBL AC104120; -; NOT_ANNOTATED_CDS; Genomic_DNA.
Sequence databasesEMBL CH471137; EAW51312.1; -; Genomic_DNA.
Sequence databasesEMBL CH471137; EAW51313.1; -; Genomic_DNA.
Sequence databasesEMBL BC030815; AAH30815.1; -; mRNA.
Sequence databasesEMBL BC094795; AAH94795.1; -; mRNA.
Sequence databasesPIR A38748; A38748.
Sequence databasesRefSeq NP_001229395.1; NM_001242466.1. [P27986-5]
Sequence databasesRefSeq NP_852556.2; NM_181504.3. [P27986-2]
Sequence databasesRefSeq NP_852664.1; NM_181523.2. [P27986-1]
Sequence databasesRefSeq NP_852665.1; NM_181524.1. [P27986-3]
Sequence databasesRefSeq XP_005248599.1; XM_005248542.1. [P27986-1]
Sequence databasesUniGene Hs.132225; -.
Sequence databasesUniGene Hs.604502; -.
Sequence databasesUniGene Hs.734132; -.
Polymorphism databasesDMDM 118572681; -.
Gene expression databasesBgee P27986; -.
Gene expression databasesCleanEx HS_PIK3R1; -.
Gene expression databasesExpressionAtlas P27986; baseline and differential.
Gene expression databasesGenevestigator P27986; -.
OntologiesGO GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB.
OntologiesGO GO:0005911; C:cell-cell junction; IEA:Ensembl.
OntologiesGO GO:0005829; C:cytosol; TAS:Reactome.
OntologiesGO GO:0016020; C:membrane; IDA:UniProtKB.
OntologiesGO GO:0005942; C:phosphatidylinositol 3-kinase complex; ISS:BHF-UCL.
OntologiesGO GO:0005886; C:plasma membrane; TAS:Reactome.
OntologiesGO GO:0043125; F:ErbB-3 class receptor binding; IDA:UniProtKB.
OntologiesGO GO:0043559; F:insulin binding; IDA:UniProtKB.
OntologiesGO GO:0005158; F:insulin receptor binding; IPI:UniProtKB.
OntologiesGO GO:0043560; F:insulin receptor substrate binding; ISS:BHF-UCL.
OntologiesGO GO:0005159; F:insulin-like growth factor receptor binding; IPI:UniProtKB.
OntologiesGO GO:0005168; F:neurotrophin TRKA receptor binding; IPI:UniProtKB.
OntologiesGO GO:0043548; F:phosphatidylinositol 3-kinase binding; ISS:BHF-UCL.
OntologiesGO GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; ISS:UniProtKB.
OntologiesGO GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
OntologiesGO GO:0005068; F:transmembrane receptor protein tyrosine kinase adaptor activity; ISS:BHF-UCL.
OntologiesGO GO:0030183; P:B cell differentiation; IEA:Ensembl.
OntologiesGO GO:0007596; P:blood coagulation; TAS:Reactome.
OntologiesGO GO:0034644; P:cellular response to UV; IEA:Ensembl.
OntologiesGO GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
OntologiesGO GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
OntologiesGO GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0060396; P:growth hormone receptor signaling pathway; IDA:BHF-UCL.
OntologiesGO GO:0045087; P:innate immune response; TAS:Reactome.
OntologiesGO GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0048009; P:insulin-like growth factor receptor signaling pathway; IPI:UniProtKB.
OntologiesGO GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
OntologiesGO GO:0050900; P:leukocyte migration; TAS:Reactome.
OntologiesGO GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
OntologiesGO GO:0001953; P:negative regulation of cell-matrix adhesion; IEA:Ensembl.
OntologiesGO GO:0045671; P:negative regulation of osteoclast differentiation; IEA:Ensembl.
OntologiesGO GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0051531; P:NFAT protein import into nucleus; IEA:Ensembl.
OntologiesGO GO:0014065; P:phosphatidylinositol 3-kinase signaling; IDA:BHF-UCL.
OntologiesGO GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
OntologiesGO GO:0046854; P:phosphatidylinositol phosphorylation; ISS:UniProtKB.
OntologiesGO GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
OntologiesGO GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
OntologiesGO GO:0030168; P:platelet activation; TAS:Reactome.
OntologiesGO GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
OntologiesGO GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; ISS:BHF-UCL.
OntologiesGO GO:0046326; P:positive regulation of glucose import; ISS:BHF-UCL.
OntologiesGO GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
OntologiesGO GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Ensembl.
OntologiesGO GO:0006468; P:protein phosphorylation; IEA:Ensembl.
OntologiesGO GO:0043551; P:regulation of phosphatidylinositol 3-kinase activity; ISS:BHF-UCL.
OntologiesGO GO:0044281; P:small molecule metabolic process; TAS:Reactome.
OntologiesGO GO:0031295; P:T cell costimulation; TAS:Reactome.
OntologiesGO GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0016032; P:viral process; IEA:UniProtKB-KW.
Proteomic databasesMaxQB P27986; -.
Proteomic databasesPaxDb P27986; -.
Proteomic databasesPRIDE P27986; -.
Family and domain databasesGene3D 1.10.555.10; -; 1.
Family and domain databasesGene3D 3.30.505.10; -; 2.
Family and domain databasesInterPro IPR001720; PI3kinase_P85.
Family and domain databasesInterPro IPR008936; Rho_GTPase_activation_prot.
Family and domain databasesInterPro IPR000198; RhoGAP_dom.
Family and domain databasesInterPro IPR000980; SH2.
Family and domain databasesInterPro IPR011511; SH3_2.
Family and domain databasesInterPro IPR001452; SH3_domain.
Family and domain databasesPANTHER PTHR10155; PTHR10155; 1.
Family and domain databasesPfam PF00620; RhoGAP; 1.
Family and domain databasesPfam PF00017; SH2; 2.
Family and domain databasesPfam PF07653; SH3_2; 1.
Family and domain databasesPRINTS PR00678; PI3KINASEP85.
Family and domain databasesPRINTS PR00401; SH2DOMAIN.
Family and domain databasesPROSITE PS50238; RHOGAP; 1.
Family and domain databasesPROSITE PS50001; SH2; 2.
Family and domain databasesPROSITE PS50002; SH3; 1.
Family and domain databasesSMART SM00324; RhoGAP; 1.
Family and domain databasesSMART SM00252; SH2; 2.
Family and domain databasesSMART SM00326; SH3; 1.
Family and domain databasesSUPFAM SSF48350; SSF48350; 1.
Family and domain databasesSUPFAM SSF50044; SSF50044; 1.
Family and domain databasesSUPFAM SSF55550; SSF55550; 2.
PTM databasesPhosphoSite P27986; -.
Protein-protein interaction databasesBioGrid 111313; 133.
Protein-protein interaction databasesDIP DIP-119N; -.
Protein-protein interaction databasesIntAct P27986; 197.
Protein-protein interaction databasesMINT MINT-93751; -.
Protein-protein interaction databasesSTRING 9606.ENSP00000274335; -.
Enzyme and pathway databasesBioCyc MetaCyc:ENSG00000145675-MONOMER; -.
Enzyme and pathway databasesReactome REACT_111040; Signaling by SCF-KIT.
Enzyme and pathway databasesReactome REACT_115529; Interleukin-7 signaling.
Enzyme and pathway databasesReactome REACT_115852; Signaling by constitutively active EGFR.
Enzyme and pathway databasesReactome REACT_115961; PI3K events in ERBB4 signaling.
Enzyme and pathway databasesReactome REACT_116008; PI3K events in ERBB2 signaling.
Enzyme and pathway databasesReactome REACT_118700; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers.
Enzyme and pathway databasesReactome REACT_121025; Synthesis of PIPs at the plasma membrane.
Enzyme and pathway databasesReactome REACT_121141; Signaling by FGFR1 fusion mutants.
Enzyme and pathway databasesReactome REACT_121398; Signaling by FGFR mutants.
Enzyme and pathway databasesReactome REACT_12464; PI3K/AKT activation.
Enzyme and pathway databasesReactome REACT_12555; Downstream TCR signaling.
Enzyme and pathway databasesReactome REACT_12578; GAB1 signalosome.
Enzyme and pathway databasesReactome REACT_12621; Tie2 Signaling.
Enzyme and pathway databasesReactome REACT_147727; Constitutive PI3K/AKT Signaling in Cancer.
Enzyme and pathway databasesReactome REACT_147814; DAP12 signaling.
Enzyme and pathway databasesReactome REACT_160158; Role of phospholipids in phagocytosis.
Enzyme and pathway databasesReactome REACT_163769; Role of LAT2/NTAL/LAB on calcium mobilization.
Enzyme and pathway databasesReactome REACT_1695; GPVI-mediated activation cascade.
Enzyme and pathway databasesReactome REACT_17025; Downstream signal transduction.
Enzyme and pathway databasesReactome REACT_18283; G alpha (q) signalling events.
Enzyme and pathway databasesReactome REACT_18407; G alpha (12/13) signalling events.
Enzyme and pathway databasesReactome REACT_19290; G beta:gamma signalling through PI3Kgamma.
Enzyme and pathway databasesReactome REACT_19344; Costimulation by the CD28 family.
Enzyme and pathway databasesReactome REACT_19358; CD28 dependent PI3K/Akt signaling.
Enzyme and pathway databasesReactome REACT_21270; PI-3K cascade.
Enzyme and pathway databasesReactome REACT_228166; VEGFA-VEGFR2 Pathway.
Enzyme and pathway databasesReactome REACT_23787; Regulation of signaling by CBL.
Enzyme and pathway databasesReactome REACT_23832; Nephrin interactions.
Enzyme and pathway databasesReactome REACT_23837; Interleukin-3, 5 and GM-CSF signaling.
Enzyme and pathway databasesReactome REACT_23847; GP1b-IX-V activation signalling.
Enzyme and pathway databasesReactome REACT_23891; Interleukin receptor SHC signaling.
Enzyme and pathway databasesReactome REACT_75829; PIP3 activates AKT signaling.
Enzyme and pathway databasesReactome REACT_976; PI3K Cascade.
Enzyme and pathway databasesSignaLink P27986; -.
3D structure databasesPDB 1A0N; NMR; -; A=91-104.
3D structure databasesPDB 1AZG; NMR; -; A=91-104.
3D structure databasesPDB 1H9O; X-ray; 1.79 A; A=617-724.
3D structure databasesPDB 1PBW; X-ray; 2.00 A; A/B=105-319.
3D structure databasesPDB 1PHT; X-ray; 2.00 A; A=1-85.
3D structure databasesPDB 1PIC; NMR; -; A=617-724.
3D structure databasesPDB 1PKS; NMR; -; A=1-79.
3D structure databasesPDB 1PKT; NMR; -; A=1-79.
3D structure databasesPDB 2IUG; X-ray; 1.89 A; A=321-440.
3D structure databasesPDB 2IUH; X-ray; 2.00 A; A=321-440.
3D structure databasesPDB 2IUI; X-ray; 2.40 A; A/B=321-440.
3D structure databasesPDB 2RD0; X-ray; 3.05 A; B=322-600.
3D structure databasesPDB 2V1Y; X-ray; 2.40 A; B=431-600.
3D structure databasesPDB 3HHM; X-ray; 2.80 A; B=322-694.
3D structure databasesPDB 3HIZ; X-ray; 3.30 A; B=322-694.
3D structure databasesPDB 3I5R; X-ray; 1.70 A; A=1-83.
3D structure databasesPDB 3I5S; X-ray; 3.00 A; A/B/C/D=1-83.
3D structure databasesPDB 4A55; X-ray; 3.50 A; B=322-600.
3D structure databasesPDB 4JPS; X-ray; 2.20 A; B=307-593.
3D structure databasesPDB 4L1B; X-ray; 2.59 A; B=318-615.
3D structure databasesPDB 4L23; X-ray; 2.50 A; B=318-615.
3D structure databasesPDB 4L2Y; X-ray; 2.80 A; B=318-615.
3D structure databasesPDB 4OVU; X-ray; 2.96 A; B=322-600.
3D structure databasesPDB 4OVV; X-ray; 3.50 A; B=322-600.
3D structure databasesPDBsum 1A0N; -.
3D structure databasesPDBsum 1AZG; -.
3D structure databasesPDBsum 1H9O; -.
3D structure databasesPDBsum 1PBW; -.
3D structure databasesPDBsum 1PHT; -.
3D structure databasesPDBsum 1PIC; -.
3D structure databasesPDBsum 1PKS; -.
3D structure databasesPDBsum 1PKT; -.
3D structure databasesPDBsum 2IUG; -.
3D structure databasesPDBsum 2IUH; -.
3D structure databasesPDBsum 2IUI; -.
3D structure databasesPDBsum 2RD0; -.
3D structure databasesPDBsum 2V1Y; -.
3D structure databasesPDBsum 3HHM; -.
3D structure databasesPDBsum 3HIZ; -.
3D structure databasesPDBsum 3I5R; -.
3D structure databasesPDBsum 3I5S; -.
3D structure databasesPDBsum 4A55; -.
3D structure databasesPDBsum 4JPS; -.
3D structure databasesPDBsum 4L1B; -.
3D structure databasesPDBsum 4L23; -.
3D structure databasesPDBsum 4L2Y; -.
3D structure databasesPDBsum 4OVU; -.
3D structure databasesPDBsum 4OVV; -.
3D structure databasesProteinModelPortal P27986; -.
3D structure databasesSMR P27986; 3-85, 115-309, 322-724.
Protocols and materials databasesDNASU 5295; -.
Phylogenomic databaseseggNOG NOG263689; -.
Phylogenomic databasesGeneTree ENSGT00390000010431; -.
Phylogenomic databasesHOVERGEN HBG082100; -.
Phylogenomic databasesInParanoid P27986; -.
Phylogenomic databasesKO K02649; -.
Phylogenomic databasesOMA LNGYNET; -.
Phylogenomic databasesOrthoDB EOG7BP831; -.
Phylogenomic databasesPhylomeDB P27986; -.
Phylogenomic databasesTreeFam TF102033; -.
Organism-specific databasesCTD 5295; -.
Organism-specific databasesGeneCards GC05P067511; -.
Organism-specific databasesHGNC HGNC:8979; PIK3R1.
Organism-specific databasesHPA CAB004268; -.
Organism-specific databasesHPA HPA001216; -.
Organism-specific databasesMIM 171833; gene.
Organism-specific databasesMIM 269880; phenotype.
Organism-specific databasesMIM 615214; phenotype.
Organism-specific databasesneXtProt NX_P27986; -.
Organism-specific databasesOrphanet 33110; Autosomal agammaglobulinemia.
Organism-specific databasesOrphanet 3163; SHORT syndrome.
Organism-specific databasesPharmGKB PA33312; -.
ChemistryBindingDB P27986; -.
ChemistryChEMBL CHEMBL2111367; -.
ChemistryDrugBank DB01064; Isoprenaline.
OtherChiTaRS PIK3R1; human.
OtherEvolutionaryTrace P27986; -.
OtherGeneWiki PIK3R1; -.
OtherGenomeRNAi 5295; -.
OtherNextBio 20462; -.
OtherPRO PR:P27986; -.



Copyright © 2016-Present - The Univsersity of Texas Health Science Center at Houston @
Site Policies | State of Texas