Cancer Cell Metabolism Gene Database

  Cancer Cell Metabolism Gene DB

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Bioinformatics and Systems Medicine Laboratory Bioinformatics and Systems Medicine Laboratory
Cross referenced IDs for 5728
* We obtained these cross-references from Uniprot database. It covers 150 different DBs, 18 categories. http://www.uniprot.org/help/cross_references_section
DB CategoryDB NameDB's ID and Url link
Genome annotation databasesEnsembl ENST00000371953; ENSP00000361021; ENSG00000171862. [P60484-1]
Genome annotation databasesGeneID 5728; -.
Genome annotation databasesKEGG hsa:5728; -.
Genome annotation databasesUCSC uc001kfb.3; human. [P60484-1]
Sequence databasesCCDS CCDS31238.1; -. [P60484-1]
Sequence databasesEMBL U96180; AAB66902.1; -; mRNA.
Sequence databasesEMBL U92436; AAC51182.1; -; mRNA.
Sequence databasesEMBL U93051; AAC51183.1; -; mRNA.
Sequence databasesEMBL AF143315; AAD38372.1; -; Genomic_DNA.
Sequence databasesEMBL AF143312; AAD38372.1; JOINED; Genomic_DNA.
Sequence databasesEMBL AF143313; AAD38372.1; JOINED; Genomic_DNA.
Sequence databasesEMBL AF143314; AAD38372.1; JOINED; Genomic_DNA.
Sequence databasesEMBL AF000734; AAC08699.1; -; Genomic_DNA.
Sequence databasesEMBL AF000726; AAC08699.1; JOINED; Genomic_DNA.
Sequence databasesEMBL AF000727; AAC08699.1; JOINED; Genomic_DNA.
Sequence databasesEMBL AF000728; AAC08699.1; JOINED; Genomic_DNA.
Sequence databasesEMBL AF000729; AAC08699.1; JOINED; Genomic_DNA.
Sequence databasesEMBL AF000730; AAC08699.1; JOINED; Genomic_DNA.
Sequence databasesEMBL AF000731; AAC08699.1; JOINED; Genomic_DNA.
Sequence databasesEMBL AF000732; AAC08699.1; JOINED; Genomic_DNA.
Sequence databasesEMBL AF000733; AAC08699.1; JOINED; Genomic_DNA.
Sequence databasesEMBL AF067844; AAD13528.1; -; Genomic_DNA.
Sequence databasesEMBL JF268690; ADZ48535.1; -; mRNA.
Sequence databasesEMBL CR450306; CAG29302.1; -; mRNA.
Sequence databasesEMBL AK313581; BAG36351.1; -; mRNA.
Sequence databasesEMBL DQ073384; AAY57327.1; -; Genomic_DNA.
Sequence databasesEMBL CH471066; EAW50174.1; -; Genomic_DNA.
Sequence databasesEMBL BC005821; AAH05821.1; -; mRNA.
Sequence databasesRefSeq NP_000305.3; NM_000314.4. [P60484-1]
Sequence databasesRefSeq XP_006717990.1; XM_006717927.1. [P60484-3]
Sequence databasesUniGene Hs.500466; -.
Polymorphism databasesDMDM 42560209; -.
Gene expression databasesBgee P60484; -.
Gene expression databasesCleanEx HS_PTEN; -.
Gene expression databasesCleanEx HS_TEP1; -.
Gene expression databasesExpressionAtlas P60484; baseline and differential.
Gene expression databasesGenevestigator P60484; -.
OntologiesGO GO:0042995; C:cell projection; IDA:UniProtKB.
OntologiesGO GO:0005737; C:cytoplasm; IDA:UniProtKB.
OntologiesGO GO:0009898; C:cytoplasmic side of plasma membrane; IDA:UniProtKB.
OntologiesGO GO:0005829; C:cytosol; TAS:Reactome.
OntologiesGO GO:0043197; C:dendritic spine; IEA:Ensembl.
OntologiesGO GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
OntologiesGO GO:0005739; C:mitochondrion; IEA:Ensembl.
OntologiesGO GO:0035749; C:myelin sheath adaxonal region; ISS:BHF-UCL.
OntologiesGO GO:0043005; C:neuron projection; ISS:BHF-UCL.
OntologiesGO GO:0005634; C:nucleus; IDA:BHF-UCL.
OntologiesGO GO:0005886; C:plasma membrane; IDA:UniProtKB.
OntologiesGO GO:0045211; C:postsynaptic membrane; IEA:Ensembl.
OntologiesGO GO:0043220; C:Schmidt-Lanterman incisure; ISS:BHF-UCL.
OntologiesGO GO:0010997; F:anaphase-promoting complex binding; IPI:BHF-UCL.
OntologiesGO GO:0019899; F:enzyme binding; IPI:UniProtKB.
OntologiesGO GO:0051717; F:inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; IDA:UniProtKB.
OntologiesGO GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
OntologiesGO GO:0000287; F:magnesium ion binding; IEA:InterPro.
OntologiesGO GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
OntologiesGO GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; IDA:UniProtKB.
OntologiesGO GO:0051800; F:phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; IDA:UniProtKB.
OntologiesGO GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:UniProtKB.
OntologiesGO GO:0004721; F:phosphoprotein phosphatase activity; IDA:BHF-UCL.
OntologiesGO GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
OntologiesGO GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
OntologiesGO GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
OntologiesGO GO:0007092; P:activation of mitotic anaphase-promoting complex activity; IDA:BHF-UCL.
OntologiesGO GO:0007568; P:aging; IEA:Ensembl.
OntologiesGO GO:0001525; P:angiogenesis; IEA:Ensembl.
OntologiesGO GO:0006915; P:apoptotic process; ISS:UniProtKB.
OntologiesGO GO:0048854; P:brain morphogenesis; ISS:BHF-UCL.
OntologiesGO GO:0060070; P:canonical Wnt signaling pathway; IDA:BHF-UCL.
OntologiesGO GO:0048738; P:cardiac muscle tissue development; IEA:Ensembl.
OntologiesGO GO:0016477; P:cell migration; ISS:UniProtKB.
OntologiesGO GO:0008283; P:cell proliferation; TAS:UniProtKB.
OntologiesGO GO:0007417; P:central nervous system development; ISS:UniProtKB.
OntologiesGO GO:0032286; P:central nervous system myelin maintenance; ISS:BHF-UCL.
OntologiesGO GO:0021955; P:central nervous system neuron axonogenesis; ISS:BHF-UCL.
OntologiesGO GO:0060997; P:dendritic spine morphogenesis; ISS:BHF-UCL.
OntologiesGO GO:0021542; P:dentate gyrus development; ISS:BHF-UCL.
OntologiesGO GO:0043542; P:endothelial cell migration; IEA:Ensembl.
OntologiesGO GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0048853; P:forebrain morphogenesis; ISS:BHF-UCL.
OntologiesGO GO:0007507; P:heart development; ISS:UniProtKB.
OntologiesGO GO:0045087; P:innate immune response; TAS:Reactome.
OntologiesGO GO:0046855; P:inositol phosphate dephosphorylation; IDA:UniProtKB.
OntologiesGO GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
OntologiesGO GO:0007611; P:learning or memory; ISS:BHF-UCL.
OntologiesGO GO:0045475; P:locomotor rhythm; ISS:BHF-UCL.
OntologiesGO GO:0007626; P:locomotory behavior; ISS:BHF-UCL.
OntologiesGO GO:0060292; P:long term synaptic depression; IEA:Ensembl.
OntologiesGO GO:0060291; P:long-term synaptic potentiation; IEA:Ensembl.
OntologiesGO GO:0060179; P:male mating behavior; IEA:Ensembl.
OntologiesGO GO:0042711; P:maternal behavior; IEA:Ensembl.
OntologiesGO GO:0007613; P:memory; IEA:Ensembl.
OntologiesGO GO:0033555; P:multicellular organismal response to stress; ISS:BHF-UCL.
OntologiesGO GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
OntologiesGO GO:0050771; P:negative regulation of axonogenesis; ISS:BHF-UCL.
OntologiesGO GO:0090344; P:negative regulation of cell aging; IEA:Ensembl.
OntologiesGO GO:0030336; P:negative regulation of cell migration; IMP:UniProtKB.
OntologiesGO GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
OntologiesGO GO:0045792; P:negative regulation of cell size; ISS:BHF-UCL.
OntologiesGO GO:0031658; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; IDA:BHF-UCL.
OntologiesGO GO:0061002; P:negative regulation of dendritic spine morphogenesis; ISS:BHF-UCL.
OntologiesGO GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
OntologiesGO GO:0090394; P:negative regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.
OntologiesGO GO:0051895; P:negative regulation of focal adhesion assembly; IMP:UniProtKB.
OntologiesGO GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IDA:BHF-UCL.
OntologiesGO GO:0031642; P:negative regulation of myelination; IEA:Ensembl.
OntologiesGO GO:0046621; P:negative regulation of organ growth; ISS:BHF-UCL.
OntologiesGO GO:0050765; P:negative regulation of phagocytosis; IEA:Ensembl.
OntologiesGO GO:0014067; P:negative regulation of phosphatidylinositol 3-kinase signaling; TAS:BHF-UCL.
OntologiesGO GO:0051898; P:negative regulation of protein kinase B signaling; IMP:UniProtKB.
OntologiesGO GO:0001933; P:negative regulation of protein phosphorylation; IDA:BHF-UCL.
OntologiesGO GO:0090071; P:negative regulation of ribosome biogenesis; IEA:Ensembl.
OntologiesGO GO:2000808; P:negative regulation of synaptic vesicle clustering; ISS:BHF-UCL.
OntologiesGO GO:0007270; P:neuron-neuron synaptic transmission; ISS:BHF-UCL.
OntologiesGO GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
OntologiesGO GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:GOC.
OntologiesGO GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
OntologiesGO GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.
OntologiesGO GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
OntologiesGO GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
OntologiesGO GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IEA:Ensembl.
OntologiesGO GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
OntologiesGO GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
OntologiesGO GO:0008284; P:positive regulation of cell proliferation; ISS:BHF-UCL.
OntologiesGO GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.
OntologiesGO GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
OntologiesGO GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.
OntologiesGO GO:0097107; P:postsynaptic density assembly; ISS:BHF-UCL.
OntologiesGO GO:0060134; P:prepulse inhibition; ISS:BHF-UCL.
OntologiesGO GO:0097105; P:presynaptic membrane assembly; ISS:BHF-UCL.
OntologiesGO GO:0060736; P:prostate gland growth; IEA:Ensembl.
OntologiesGO GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.
OntologiesGO GO:0043491; P:protein kinase B signaling; ISS:UniProtKB.
OntologiesGO GO:0050821; P:protein stabilization; IDA:BHF-UCL.
OntologiesGO GO:0002902; P:regulation of B cell apoptotic process; IEA:Ensembl.
OntologiesGO GO:0032535; P:regulation of cellular component size; ISS:BHF-UCL.
OntologiesGO GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:UniProtKB.
OntologiesGO GO:0033032; P:regulation of myeloid cell apoptotic process; IEA:Ensembl.
OntologiesGO GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB.
OntologiesGO GO:0031647; P:regulation of protein stability; IMP:UniProtKB.
OntologiesGO GO:0046685; P:response to arsenic-containing substance; IEA:Ensembl.
OntologiesGO GO:0033198; P:response to ATP; IEA:Ensembl.
OntologiesGO GO:0042493; P:response to drug; IEA:Ensembl.
OntologiesGO GO:0032355; P:response to estradiol; IEA:Ensembl.
OntologiesGO GO:0045471; P:response to ethanol; IEA:Ensembl.
OntologiesGO GO:0009749; P:response to glucose; IEA:Ensembl.
OntologiesGO GO:0007584; P:response to nutrient; IEA:Ensembl.
OntologiesGO GO:0010043; P:response to zinc ion; IEA:Ensembl.
OntologiesGO GO:0060024; P:rhythmic synaptic transmission; ISS:BHF-UCL.
OntologiesGO GO:0044281; P:small molecule metabolic process; TAS:Reactome.
OntologiesGO GO:0035176; P:social behavior; ISS:BHF-UCL.
OntologiesGO GO:0007416; P:synapse assembly; ISS:BHF-UCL.
OntologiesGO GO:0060074; P:synapse maturation; ISS:BHF-UCL.
OntologiesGO GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
Proteomic databasesMaxQB P60484; -.
Proteomic databasesPaxDb P60484; -.
Proteomic databasesPRIDE P60484; -.
Family and domain databasesGene3D 3.90.190.10; -; 1.
Family and domain databasesInterPro IPR017361; Bifunc_PIno_P3_Pase/Pase_PTEN.
Family and domain databasesInterPro IPR000008; C2_dom.
Family and domain databasesInterPro IPR000340; Dual-sp_phosphatase_cat-dom.
Family and domain databasesInterPro IPR029021; Prot-tyrosine_phosphatase-like.
Family and domain databasesInterPro IPR014020; Tensin_C2-dom.
Family and domain databasesInterPro IPR029023; Tensin_lipid_phosphatase_dom.
Family and domain databasesInterPro IPR016130; Tyr_Pase_AS.
Family and domain databasesPfam PF00782; DSPc; 1.
Family and domain databasesPfam PF10409; PTEN_C2; 1.
Family and domain databasesPIRSF PIRSF038025; PTEN; 1.
Family and domain databasesPROSITE PS51182; C2_TENSIN; 1.
Family and domain databasesPROSITE PS51181; PPASE_TENSIN; 1.
Family and domain databasesSUPFAM SSF49562; SSF49562; 1.
Family and domain databasesSUPFAM SSF52799; SSF52799; 1.
PTM databasesPhosphoSite P60484; -.
Protein-protein interaction databasesBioGrid 111700; 90.
Protein-protein interaction databasesDIP DIP-35019N; -.
Protein-protein interaction databasesIntAct P60484; 41.
Protein-protein interaction databasesMINT MINT-127351; -.
Protein-protein interaction databasesSTRING 9606.ENSP00000361021; -.
Enzyme and pathway databasesBioCyc MetaCyc:HS10404-MONOMER; -.
Enzyme and pathway databasesReactome REACT_121025; Synthesis of PIPs at the plasma membrane.
Enzyme and pathway databasesReactome REACT_12447; Negative regulation of the PI3K/AKT network.
Enzyme and pathway databasesReactome REACT_12555; Downstream TCR signaling.
Enzyme and pathway databasesReactome REACT_147727; Constitutive PI3K/AKT Signaling in Cancer.
Enzyme and pathway databasesReactome REACT_150312; Synthesis of IP3 and IP4 in the cytosol.
Enzyme and pathway databasesReactome REACT_75829; PIP3 activates AKT signaling.
Enzyme and pathway databasesSignaLink P60484; -.
3D structure databasesPDB 1D5R; X-ray; 2.10 A; A=8-353.
3D structure databasesPDB 2KYL; NMR; -; B=391-403.
3D structure databasesPDB 4O1V; X-ray; 2.00 A; B=354-368.
3D structure databasesPDBsum 1D5R; -.
3D structure databasesPDBsum 2KYL; -.
3D structure databasesPDBsum 4O1V; -.
3D structure databasesProteinModelPortal P60484; -.
3D structure databasesSMR P60484; 14-351.
Protocols and materials databasesDNASU 5728; -.
Phylogenomic databaseseggNOG COG2453; -.
Phylogenomic databasesGeneTree ENSGT00760000119113; -.
Phylogenomic databasesHOGENOM HOG000008008; -.
Phylogenomic databasesHOVERGEN HBG000239; -.
Phylogenomic databasesInParanoid P60484; -.
Phylogenomic databasesKO K01110; -.
Phylogenomic databasesOMA KEYLILT; -.
Phylogenomic databasesOrthoDB EOG7R2BJ5; -.
Phylogenomic databasesPhylomeDB P60484; -.
Phylogenomic databasesTreeFam TF324513; -.
Organism-specific databasesCTD 5728; -.
Organism-specific databasesGeneCards GC10P089613; -.
Organism-specific databasesGeneReviews PTEN; -.
Organism-specific databasesHGNC HGNC:9588; PTEN.
Organism-specific databasesHPA CAB004076; -.
Organism-specific databasesHPA HPA031335; -.
Organism-specific databasesMIM 137800; phenotype.
Organism-specific databasesMIM 153480; phenotype.
Organism-specific databasesMIM 158350; phenotype.
Organism-specific databasesMIM 176807; phenotype.
Organism-specific databasesMIM 275355; phenotype.
Organism-specific databasesMIM 276950; phenotype.
Organism-specific databasesMIM 601728; gene.
Organism-specific databasesMIM 605309; phenotype.
Organism-specific databasesMIM 608089; phenotype.
Organism-specific databasesMIM 612242; phenotype.
Organism-specific databasesMIM 613028; phenotype.
Organism-specific databasesneXtProt NX_P60484; -.
Organism-specific databasesOrphanet 109; Bannayan-Riley-Ruvalcaba syndrome.
Organism-specific databasesOrphanet 201; Cowden syndrome.
Organism-specific databasesOrphanet 145; Hereditary breast and ovarian cancer syndrome.
Organism-specific databasesOrphanet 79076; Juvenile polyposis of infancy.
Organism-specific databasesOrphanet 65285; Lhermitte-Duclos disease.
Organism-specific databasesOrphanet 210548; Macrocephaly-autism syndrome.
Organism-specific databasesOrphanet 744; Proteus syndrome.
Organism-specific databasesOrphanet 2969; Proteus-like syndrome.
Organism-specific databasesOrphanet 137608; Segmental outgrowth - lipomatosis - arteriovenous malformation - epidermal nevus.
Organism-specific databasesOrphanet 67037; Squamous cell carcinoma of head and neck.
Organism-specific databasesPharmGKB PA33942; -.
ChemistryBindingDB P60484; -.
ChemistryChEMBL CHEMBL2052032; -.
OtherChiTaRS PTEN; human.
OtherEvolutionaryTrace P60484; -.
OtherGeneWiki PTEN_(gene); -.
OtherGenomeRNAi 5728; -.
OtherNextBio 22282; -.
OtherPMAP-CutDB P60484; -.
OtherPRO PR:P60484; -.



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