mutLBSgeneDB

mutLBSgeneDB
mutated Ligand Binding Site gene DataBase

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Bioinformatics and Systems Medicine Laboratory Bioinformatics and Systems Medicine Laboratory

Gene Summary

Ligand Binding Site Mutation Information

Protein Structure Related Information

Gene Expression and Gene-Gene Network

Phenotype Information

Pharmacological Information

Conservation Information for LBS

Gene summary for DPP4
Gene summary
Basic gene Info.Gene symbolDPP4
Gene namedipeptidyl-peptidase 4
SynonymsADABP|ADCP2|CD26|DPPIV|TP103
CytomapUCSC genome browser: 2q24.3
Type of geneprotein-coding
RefGenesNM_001935.3,
DescriptionADCP-2DPP IVT-cell activation antigen CD26adenosine deaminase complexing protein 2dipeptidyl peptidase 4dipeptidyl peptidase IVdipeptidylpeptidase 4dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2)
Modification date20141222
dbXrefs MIM : 102720
HGNC : HGNC
Ensembl : ENSG00000197635
HPRD : 02187
Vega : OTTHUMG00000132056
ProteinUniProt: P27487
go to UniProt's Cross Reference DB Table
ExpressionCleanEX: HS_DPP4
BioGPS: 1803
PathwayNCI Pathway Interaction Database: DPP4
KEGG: DPP4
REACTOME: DPP4
Pathway Commons: DPP4
ContextiHOP: DPP4
ligand binding site mutation search in PubMed: DPP4
UCL Cancer Institute: DPP4
Assigned class in mutLBSgeneDBB: This gene belongs to targetable_mutLBSgenes.

Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez
GO IDGO TermPubMed ID
GO:0001666response to hypoxia16670267
GO:0008284positive regulation of cell proliferation17549790
GO:0010716negative regulation of extracellular matrix disassembly16651416
GO:0031295T cell costimulation10900005
GO:0033632regulation of cell-cell adhesion mediated by integrin11772392
GO:0042110T cell activation7594462
GO:0043542endothelial cell migration16651416


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Ligand binding site mutations for DPP4
Lollipop-style diagram of mutations at LBS in amino-acid sequence.
We represented ligand binding site mutations only. (You can see big image via clicking.)
 
: non-synonymous mutation on LBS, Circle size denotes number of samples.

Cancer type specific mutLBS sorted by frequency
LBSAAchange of nsSNVCancer type# samples
G741G741EBRCA1
Q308A306VCOAD1
G741A743THNSC1
R253R253LLUAD1
H126S127FLUAD1
G220G220SLUAD1
Q308A306TOV1
E309R310GOV1
R581G582ESKCM1
G741G741RSKCM1
T231,N229D230NSTAD1
H748A747SUCEC1
Q123V121MUCEC1
E309R310IUCEC1
S360S360PUCEC1
Y585Y585HUCEC1
E309E309GUCEC1
D545L544VUCEC1
Y666E668KUCEC1
D545D545YUCEC1
cf) Cancer type abbreviation. BLCA: Bladder urothelial carcinoma, BRCA: Breast invasive carcinoma, CESC: Cervical squamous cell carcinoma and endocervical adenocarcinoma, COAD: Colon adenocarcinoma, GBM: Glioblastoma multiforme, LGG: Brain lower grade glioma, HNSC: Head and neck squamous cell carcinoma, KICH: Kidney chromophobe, KIRC: Kidney renal clear cell carcinoma, KIRP: Kidney renal papillary cell carcinoma, LAML: Acute myeloid leukemia, LUAD: Lung adenocarcinoma, LUSC: Lung squamous cell carcinoma, OV: Ovarian serous cystadenocarcinoma, PAAD: Pancreatic adenocarcinoma, PRAD: Prostate adenocarcinoma, SKCM: Skin cutaneous melanoma, STAD: Stomach adenocarcinoma, THCA: Thyroid carcinoma, UCEC: Uterine corpus endometrial carcinoma.


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Protein structure related information for DPP4
Relative protein structure stability change (ΔΔE) using Mupro 1.1
Mupro score denotes assessment of the effect of mutations on thermodynamic stability.
  (ΔΔE<0: mutation decreases stability, ΔΔE>0: mutation increases stability)
: nsSNV at non-LBS: nsSNV at LBS

nsSNVs sorted by the relative stability change of protein structure by each mutation
Blue: mutations of positive stability change. and red : the most recurrent mutation for this gene.
LBSAAchange of nsSNVRelative stability change
R581G582E0.12286332
Q123V121M-1.4367588
Y585Y585H-1.3494026
D545L544V-1.3066888
E309E309G-1.1312678
E309R310G-1.1276165
H748A747S-0.87633989
Q308A306T-0.76306703
N229D230N-0.71326986
T231D230N-0.71326986
Y666E668K-0.71312831
G220G220S-0.62478414
G741G741R-0.51645317
Q308A306V-0.51291235
R253R253L-0.49715186
G741G741E-0.49576092
D545D545Y-0.49094869
G741A743T-0.45287254
E309R310I-0.42889798
H126S127F-0.33184272
S360S360P-0.032697699
(MuPro1.1: Jianlin Cheng et al., Prediction of Protein Stability Changes for Single-Site Mutations Using Support Vector Machines, PROTEINS: Structure, Function, and Bioinformatics. 2006, 62:1125-1132)

Structure image for DPP4 from PDB

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Differential gene expression and gene-gene network for DPP4
Differential gene expression between mutated and non-mutated LBS samples in all 16 major cancer types

Differential co-expressed gene network based on protein-protein interaction data (CePIN)
* Left PPI network was created from samples with mutations in the LBS of DPP4 and the right PPI network was created from samples without mutations in the LBS of DPP4. Only genes with p-value < 0.05 are shown.
Red circle: input gene. Orange circle: LBSgene. Blue circle: other gene.


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Phenotype information for DPP4
Gene level disease information (DisGeNet)
Disease IDDisease name# PubMedAssociation type
umls:C0033687Proteinuria1Biomarker

Mutation level pathogenic information (ClinVar annotation)
Allele IDAA changeClinical significanceOriginPhenotype IDs

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Pharmacological information for DPP4
Gene expression profile of anticancer drug treated cell-lines (CCLE)
Heatmap showing the correlation between gene expression and drug response across all the cell-lines. We chose the top 20 among 138 drugs.We used Pearson's correlation coefficient.

Gene-centered drug-gene interaction network
Drug information targeting mutLBSgene (Approved drugs only)
Drug statusDrugBank IDNameTypeDrug structure
ApprovedDB01076AtorvastatinSmall molecule
Approved|investigationalDB01261SitagliptinSmall molecule
ExperimentalDB018842-Amino-3-Methyl-1-Pyrrolidin-1-Yl-Butan-1-OneSmall molecule
ExperimentalDB020045-(Aminomethyl)-6-(2,4-Dichlorophenyl)-2-(3,5-Dimethoxyphenyl)Pyrimidin-4-AmineSmall molecule
ExperimentalDB03253(2s)-Pyrrolidin-2-YlmethylamineSmall molecule
ExperimentalDB036604-Iodo-L-phenylalanineSmall molecule
ExperimentalDB04491Diisopropylphosphono GroupSmall molecule
ExperimentalDB045771-(1-phenylcyclopentyl)methylamineSmall molecule
ExperimentalDB04578(S)-2-[(R)-3-amino-4-(2-fluorophenyl)butyryl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamideSmall molecule
Approved|investigationalDB04876VildagliptinSmall molecule
InvestigationalDB05001PSN9301Small molecule
InvestigationalDB05065PHX1149Small molecule
InvestigationalDB06127KRP-104Small molecule
ApprovedDB06203AlogliptinSmall molecule
ApprovedDB06335SaxagliptinSmall molecule
ExperimentalDB06880(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-PROP-1-YN-1-YLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINESmall molecule
ExperimentalDB06939N-(TRANS-4-{(1S,2S)-2-AMINO-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-METHYL-3-OXOPROPYL}CYCLOHEXYL)-N-METHYLACETAMIDESmall molecule
ExperimentalDB06993(2S,3S)-4-cyclopropyl-3-{(3R,5R)-3-[2-fluoro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazolidin-5-yl}-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-amineSmall molecule
ExperimentalDB06994(2S,3S)-3-{3-[2-chloro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-cyclopentylidene-4-cyclopropyl-1-fluorobutan-2-amineSmall molecule
ExperimentalDB07015(3R,4R)-4-(pyrrolidin-1-ylcarbonyl)-1-(quinoxalin-2-ylcarbonyl)pyrrolidin-3-amineSmall molecule
ExperimentalDB07021(7R,8R)-8-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydroimidazo[1,2-a:4,5-c']dipyridin-7-amineSmall molecule
ExperimentalDB07067(2S,3S)-3-{3-[4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-1-OXO-1-PYRROLIDIN-1-YLBUTAN-2-AMINESmall molecule
ExperimentalDB07072(1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINESmall molecule
ExperimentalDB07081(2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRAZIN-7(8H)-YL]-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINESmall molecule
ExperimentalDB07092(2S,3S)-3-AMINO-4-(3,3-DIFLUOROPYRROLIDIN-1-YL)-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-6-YLCYCLOHEXYL)BUTANAMIDESmall molecule
ExperimentalDB07135(2S,3S)-3-AMINO-4-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-5-YLCYCLOHEXYL)BUTANAMIDESmall molecule
ExperimentalDB07154(3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-METHYL-1,4-DIAZEPAN-2-ONESmall molecule
ExperimentalDB071814'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]biphenyl-3-carboxamideSmall molecule
ExperimentalDB07193(2R,3R)-7-(methylsulfonyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amineSmall molecule
ExperimentalDB072397-(aminomethyl)-6-(2-chlorophenyl)-1-methyl-1H-benzimidazole-5-carbonitrileSmall molecule
ExperimentalDB07271(3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-(2,2,2-TRIFLUOROETHYL)-1,4-DIAZEPAN-2-ONESmall molecule
ExperimentalDB07328METHYL 4-{[({[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHYL}AMINO)CARBONYL]AMINO}BENZOATESmall molecule
ExperimentalDB07356(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-ETHYNYLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINESmall molecule
ExperimentalDB074121-biphenyl-2-ylmethanamineSmall molecule
ExperimentalDB07465(1S,3S,5S)-2-{(2S)-2-amino-2-[(1R,3S,5R,7S)-3-hydroxytricyclo[3.3.1.1~3,7~]dec-1-yl]acetyl}-2-azabicyclo[3.1.0]hexane-3-carbonitrileSmall molecule
ExperimentalDB07482(2R)-N-[(2R)-2-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-N-[(5R)-5-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-L-PROLINAMIDESmall molecule
ExperimentalDB07666(3R,4S)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINESmall molecule
ExperimentalDB07779N-({(2S)-1-[(3R)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOYL]PYRROLIDIN-2-YL}METHYL)BENZAMIDESmall molecule
ExperimentalDB07830(4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONESmall molecule
ExperimentalDB07851(3R,4S)-1-(3,4-DIMETHOXYPHENYL)-3-(3-METHYLPHENYL)PIPERIDIN-4-AMINESmall molecule
ExperimentalDB080241-[2-(S)-AMINO-3-BIPHENYL-4-YL-PROPIONYL]-PYRROLIDINE-2-(S)-CARBONITRILESmall molecule
ExperimentalDB08044(1S,6R)-3-{[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]CARBONYL}-6-(2,4,5-TRIFLUOROPHENYL)CYCLOHEX-3-EN-1-AMINESmall molecule
ExperimentalDB08051(2R)-4-(2-BENZOYL-1,2-DIAZEPAN-1-YL)-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINESmall molecule
ExperimentalDB08164(3R,4R)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-3-AMINESmall molecule
ExperimentalDB083822-(4-{(3S,5S)-5-[(3,3-difluoropyrrolidin-1-yl)carbonyl]pyrrolidin-3-yl}piperazin-1-yl)pyrimidineSmall molecule
ExperimentalDB08429N-({(2S)-1-[(3R)-3-amino-4-(3-chlorophenyl)butanoyl]pyrrolidin-2-yl}methyl)-3-(methylsulfonyl)benzamideSmall molecule
ExperimentalDB08445(3R,4S)-1-[6-(6-METHOXYPYRIDIN-3-YL)PYRIMIDIN-4-YL]-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINESmall molecule
ExperimentalDB085046-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL)-1H-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-4-IUMSmall molecule
ExperimentalDB085307-BENZYL-1,3-DIMETHYL-8-PIPERAZIN-1-YL-3,7-DIHYDRO-PURINE-2,6-DIONESmall molecule
ExperimentalDB085882-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILESmall molecule
ExperimentalDB086724-[(3R)-3-{[2-(4-FLUOROPHENYL)-2-OXOETHYL]AMINO}BUTYL]BENZAMIDESmall molecule
ExperimentalDB087432-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILESmall molecule
ApprovedDB08882LinagliptinSmall molecule

Gene-centered ligand-gene interaction network

Ligands binding to mutated ligand binding site of DPP4 go to BioLip
Ligand IDLigand short nameLigand long namePDB IDPDB namemutLBS
N7F6-[(3S)-3-AMINOPIPERIDIN-1-YL]-5-BENZYL-4-OXO-3-(QUINOLIN-4-YLMETHYL)-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDINE-7-CARBONITRILE4a5sAD545 Y666
N7F6-[(3S)-3-AMINOPIPERIDIN-1-YL]-5-BENZYL-4-OXO-3-(QUINOLIN-4-YLMETHYL)-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDINE-7-CARBONITRILE4a5sBD545 Y666
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0bAE309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0gDG220 Q308
ACF3-{[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHOXY}-4-CHLOROBENZOICACID2g5tAH126 Y666
AXD2-[4-({2-[(2S,5R)-2-(AMINOMETHYL)-5-ETHYNYLPYRROLIDIN-1-YL]-2-OXOETHYL}AMINO)-4-METHYLPIPERIDIN-1-YL]ISONICOTINIC ACID2i03BH126 Y666
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE1tk3AN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE1tk3BN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE1tkrAN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE1tkrBN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE1u8eAN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2iitAN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2iitBN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2iivAN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2iivBN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2oncAN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2oncBN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2oncCN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2oncDN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2qoeAN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2qoeBN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2qt9AN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2qt9BN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2qtbAN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2qtbBN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2rguAN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2rguBN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3bjmAN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3bjmBN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0bAN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0bBN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0bCN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0bDN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0cAN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0cBN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0cCN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0cDN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0dAN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0dBN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0dCN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0dDN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0gAN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0gBN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0gCN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0gDN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3vjkAN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3vjkBN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3vjlAN229 T231
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3vjlBN229 T231
SY12-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE2oncAQ123 R253
SY12-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE2oncBQ123 R253
SY12-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE2oncCQ123 R253
SY12-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE2oncDQ123 R253
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0gCQ308
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE1tk3AQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE1tkrAQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2iitAQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2iitBQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2iivAQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2iivBQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2oncAQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2oncBQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2oncCQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2qoeAQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2qoeBQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2qt9AQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2qt9BQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2qtbAQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE2qtbBQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0bBQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0bDQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0cAQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0cBQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0cCQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0dAQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0dBQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0dCQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0gAQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0gBQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3vjkAQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3vjkBQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3vjlAQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3vjlBQ308 E309
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE1tk3AR581
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE1tk3BR581
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE1u8eAR581
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE1u8eBR581
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0bAR581
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0bCR581
NAGALDEHYDO-N-ACETYL-D-GLUCOSAMINE3g0bDR581
D5CN-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTYL]-3'- (TRIFLUOROMETHYL)BIPHENYL-4-CARBOXAMIDE4dtcBS360 Y666
KIQ(1S,6R)-3-{[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]CARBONYL}-6-(2,4,5-TRIFLUOROPHENYL)CYCLOHEX-3-EN-1-AMINE2i78BY585 Y666
448(2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRAZIN-7(8H)-YL]-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE2qoeAY585 Y666
448(2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRAZIN-7(8H)-YL]-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE2qoeBY585 Y666
AJH4-({4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-1,4-DIAZEPAN-1-YL}CARBONYL)BENZOIC ACID3eioAY585 Y666
AJH4-({4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-1,4-DIAZEPAN-1-YL}CARBONYL)BENZOIC ACID3eioBY585 Y666
PF22-(4-{(3S,5S)-5-[(3,3-DIFLUOROPYRROLIDIN-1-YL)CARBONYL]PYRROLIDIN-3-YL}PIPERAZIN-1-YL)PYRIMIDINE3f8sAY585 Y666
W611,3-THIAZOLIDIN-3-YL[(2S,4S)-4-{4-[2-(TRIFLUOROMETHYL) QUINOLIN-4-YL]PIPERAZIN-1-YL}PYRROLIDIN-2-YL]METHANONE3vjmAY585 Y666
W611,3-THIAZOLIDIN-3-YL[(2S,4S)-4-{4-[2-(TRIFLUOROMETHYL) QUINOLIN-4-YL]PIPERAZIN-1-YL}PYRROLIDIN-2-YL]METHANONE3vjmBY585 Y666
SKKANAGLIPTINN-[2-({2-[(2S)-2-CYANOPYRROLIDIN-1-YL]-2- OXOETHYL}AMINO)-2-METHYLPROPYL]-2-METHYLPYRAZOLO[1,5- A]PYRIMIDINE-6-CARBOXAMIDE3wqhAY585 Y666
SKKANAGLIPTINN-[2-({2-[(2S)-2-CYANOPYRROLIDIN-1-YL]-2- OXOETHYL}AMINO)-2-METHYLPROPYL]-2-METHYLPYRAZOLO[1,5- A]PYRIMIDINE-6-CARBOXAMIDE3wqhBY585 Y666
A3M2-AMINO-3-METHYL-1-PYRROLIDIN-1-YL-BUTAN-1-ONE1n1mAY666
A3M2-AMINO-3-METHYL-1-PYRROLIDIN-1-YL-BUTAN-1-ONE1n1mBY666
IIIPeptide ligand (ILE,PRO,ILE)1nu8BY666
5AP5-(AMINOMETHYL)-6-(2,4-DICHLOROPHENYL)-2-(3,5-DIMETHOXYPHENYL)PYRIMIDIN-4-AMINE1rwqAY666
5AP5-(AMINOMETHYL)-6-(2,4-DICHLOROPHENYL)-2-(3,5-DIMETHOXYPHENYL)PYRIMIDIN-4-AMINE1rwqBY666
DFPDIISOPROPYL PHOSPHITE1tkrAY666
DFPDIISOPROPYL PHOSPHITE1tkrBY666
IIIPeptide ligand (ILE,PRO,ILE)1wcyAY666
IIIPeptide ligand (ILE,PRO,ILE)1wcyBY666
715SITAGLIPTIN1x70AY666
715SITAGLIPTIN1x70BY666
JNH(2S)-2-CYANO-1-(4-PHENYL-L-PHENYLALANYL)PYRROLIDINE2ajlIY666
JNH(2S)-2-CYANO-1-(4-PHENYL-L-PHENYLALANYL)PYRROLIDINE2ajlJY666
IIIPeptide ligand (MET,TRP,PRO,VAL,ASP,PRO)2bgnAY666
IIIPeptide ligand (MET,TRP,PRO,VAL,ASP,PRO)2bgnCY666
IIIPeptide ligand (MET,TRP,PRO,VAL,ASP,PRO)2bgnDY666
IIIPeptide ligand (MET,ASP,PRO)2bgrAY666
IIIPeptide ligand (MET,ASP,PRO)2bgrBY666
FPBN-({(2S)-1-[(3R)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOYL]PYRROLIDIN-2-YL}METHYL)BENZAMIDE2bubAY666
FPBN-({(2S)-1-[(3R)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOYL]PYRROLIDIN-2-YL}METHYL)BENZAMIDE2bubBY666
S146-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL)-1H-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-4-IUM2fjpAY666
S146-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL)-1H-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-4-IUM2fjpBY666
ADF4-{[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHOXY}-3-TERT-BUTYLBENZOIC ACID2g5pAY666
AAFMETHYL 4-{[({[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHYL}AMINO)CARBONYL]AMINO}BENZOATE2g63BY666
3TP(2S,3S)-3-{3-[4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-1-OXO-1-PYRROLIDIN-1-YLBUTAN-2-AMINE2hhaAY666
3TP(2S,3S)-3-{3-[4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-1-OXO-1-PYRROLIDIN-1-YLBUTAN-2-AMINE2hhaBY666
872(3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-(2,2,2-TRIFLUOROETHYL)-1,4-DIAZEPAN-2-ONE2iitAY666
872(3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-(2,2,2-TRIFLUOROETHYL)-1,4-DIAZEPAN-2-ONE2iitBY666
565(3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-METHYL-1,4-DIAZEPAN-2-ONE2iivAY666
565(3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-METHYL-1,4-DIAZEPAN-2-ONE2iivBY666
GVB1-(3,4-DIMETHOXY-PHENYL)-3-M-TOLYL-PIPERIDINE-4-YLAMINE2jidAY666
GVB1-(3,4-DIMETHOXY-PHENYL)-3-M-TOLYL-PIPERIDINE-4-YLAMINE2jidBY666
DLI(3R,4S)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE2oagBY666
U1N4-[(3R)-3-{[2-(4-FLUOROPHENYL)-2-OXOETHYL]AMINO}BUTYL]BENZAMIDE2ogzAY666
U1N4-[(3R)-3-{[2-(4-FLUOROPHENYL)-2-OXOETHYL]AMINO}BUTYL]BENZAMIDE2ogzBY666
KR2(R)-3-AMINO-1-(2-BENZOYL-1,2-DIAZEPAN-1-YL)-4-(2,4,5-TRIFLUOROPHENYL)BUTAN-1-ONE2oleAY666
KR2(R)-3-AMINO-1-(2-BENZOYL-1,2-DIAZEPAN-1-YL)-4-(2,4,5-TRIFLUOROPHENYL)BUTAN-1-ONE2oleBY666
SY12-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE2oncAY666
SY12-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE2oncBY666
SY12-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE2oncCY666
SY12-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE2oncDY666
277N-(TRANS-4-{(1S,2S)-2-AMINO-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-METHYL-3-OXOPROPYL}CYCLOHEXYL)-N-METHYLACETAMIDE2ophAY666
277N-(TRANS-4-{(1S,2S)-2-AMINO-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-METHYL-3-OXOPROPYL}CYCLOHEXYL)-N-METHYLACETAMIDE2ophBY666
GGO(4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONE2oqiBY666
MA9(3R,4R)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-3-AMINE2oqvAY666
417(1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE2p8sAY666
417(1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE2p8sBY666
PZF(3R,4S)-1-[6-(6-METHOXYPYRIDIN-3-YL)PYRIMIDIN-4-YL]-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE2qjrAY666
PZF(3R,4S)-1-[6-(6-METHOXYPYRIDIN-3-YL)PYRIMIDIN-4-YL]-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE2qjrBY666
13Z2-[(2-{(2S,4S)-2-[(R)-(5-TERT-BUTYL-1,3,4-OXADIAZOL-2-YL)(HYDROXY)METHYL]-4-FLUOROPYRROLIDIN-1-YL}-2-OXOETHYL)AMINO]-2-METHYLPROPAN-1-OL2qkyAY666
13Z2-[(2-{(2S,4S)-2-[(R)-(5-TERT-BUTYL-1,3,4-OXADIAZOL-2-YL)(HYDROXY)METHYL]-4-FLUOROPYRROLIDIN-1-YL}-2-OXOETHYL)AMINO]-2-METHYLPROPAN-1-OL2qkyBY666
13Z2-[(2-{(2S,4S)-2-[(R)-(5-TERT-BUTYL-1,3,4-OXADIAZOL-2-YL)(HYDROXY)METHYL]-4-FLUOROPYRROLIDIN-1-YL}-2-OXOETHYL)AMINO]-2-METHYLPROPAN-1-OL2qkyCY666
13Z2-[(2-{(2S,4S)-2-[(R)-(5-TERT-BUTYL-1,3,4-OXADIAZOL-2-YL)(HYDROXY)METHYL]-4-FLUOROPYRROLIDIN-1-YL}-2-OXOETHYL)AMINO]-2-METHYLPROPAN-1-OL2qkyDY666
5245-(4-{(1S,2S)-2-AMMONIO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}CYCLOHEXYL)[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-1-IUM2qt9AY666
5245-(4-{(1S,2S)-2-AMMONIO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}CYCLOHEXYL)[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-1-IUM2qt9BY666
4746-(4-{(1S,2S)-2-AMMONIO-3-(3,3-DIFLUOROPYRROLIDIN-1-YL)-1-[(DIMETHYLAMINO)CARBONYL] -3-OXOPROPYL}CYCLOHEXYL)[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-1-IUM2qtbAY666
4746-(4-{(1S,2S)-2-AMMONIO-3-(3,3-DIFLUOROPYRROLIDIN-1-YL)-1-[(DIMETHYLAMINO)CARBONYL] -3-OXOPROPYL}CYCLOHEXYL)[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-1-IUM2qtbBY666
3568-[(3R)-3-AMINOPIPERIDIN-1-YL]-7-BUT-2-YN-1-YL-3-METHYL-1-[(4-METHYLQUINAZOLIN-2-YL)METHYL]-3,7-DIHYDRO-1H-PURINE-2,6-DIONE2rguAY666
3568-[(3R)-3-AMINOPIPERIDIN-1-YL]-7-BUT-2-YN-1-YL-3-METHYL-1-[(4-METHYLQUINAZOLIN-2-YL)METHYL]-3,7-DIHYDRO-1H-PURINE-2,6-DIONE2rguBY666
34Q(3R,4R)-4-(PYRROLIDIN-1-YLCARBONYL)-1-(QUINOXALIN-2-YLCARBONYL)PYRROLIDIN-3-AMINE2ripAY666
BJM(1S,3S,5S)-2-{(2S)-2-AMINO-2-[(1R,3S,5R,7S)-3-HYDROXYTRICYCLO[3.3.1.1~3,7~]DEC-1-YL]ACETYL}-2-AZABICYCLO[3.1.0]HEXANE-3-CARBONITRILE3bjmAY666
BJM(1S,3S,5S)-2-{(2S)-2-AMINO-2-[(1R,3S,5R,7S)-3-HYDROXYTRICYCLO[3.3.1.1~3,7~]DEC-1-YL]ACETYL}-2-AZABICYCLO[3.1.0]HEXANE-3-CARBONITRILE3bjmBY666
315(2S,3S)-4-CYCLOPROPYL-3-{(3R,5R)-3-[2-FLUORO-4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOLIDIN-5-YL}-1-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-OXOBUTAN-2-AMINE3c43AY666
315(2S,3S)-4-CYCLOPROPYL-3-{(3R,5R)-3-[2-FLUORO-4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOLIDIN-5-YL}-1-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-OXOBUTAN-2-AMINE3c43BY666
317(2S,3S)-3-{3-[2-CHLORO-4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-1-CYCLOPENTYLIDENE-4-CYCLOPROPYL-1-FLUOROBUTAN-2-AMINE3c45AY666
317(2S,3S)-3-{3-[2-CHLORO-4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-1-CYCLOPENTYLIDENE-4-CYCLOPROPYL-1-FLUOROBUTAN-2-AMINE3c45BY666
B2Y1-BIPHENYL-2-YLMETHANAMINE3ccbAY666
B2Y1-BIPHENYL-2-YLMETHANAMINE3ccbBY666
B2Y1-BIPHENYL-2-YLMETHANAMINE3ccbCY666
B2Y1-BIPHENYL-2-YLMETHANAMINE3ccbDY666
7AC7-(AMINOMETHYL)-6-(2-CHLOROPHENYL)-1-METHYL-1H-BENZIMIDAZOLE-5-CARBONITRILE3cccAY666
7AC7-(AMINOMETHYL)-6-(2-CHLOROPHENYL)-1-METHYL-1H-BENZIMIDAZOLE-5-CARBONITRILE3cccBY666
7AC7-(AMINOMETHYL)-6-(2-CHLOROPHENYL)-1-METHYL-1H-BENZIMIDAZOLE-5-CARBONITRILE3cccCY666
7AC7-(AMINOMETHYL)-6-(2-CHLOROPHENYL)-1-METHYL-1H-BENZIMIDAZOLE-5-CARBONITRILE3cccDY666
6054'-[(1R)-1-AMINO-2-(2,5-DIFLUOROPHENYL)ETHYL]BIPHENYL-3-CARBOXAMIDE3d4lAY666
6054'-[(1R)-1-AMINO-2-(2,5-DIFLUOROPHENYL)ETHYL]BIPHENYL-3-CARBOXAMIDE3d4lBY666
PF22-(4-{(3S,5S)-5-[(3,3-DIFLUOROPYRROLIDIN-1-YL)CARBONYL]PYRROLIDIN-3-YL}PIPERAZIN-1-YL)PYRIMIDINE3f8sBY666
T222-({6-[(3R)-3-AMINOPIPERIDIN-1-YL]-3-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL}METHYL)BENZONITRILE3g0bAY666
T222-({6-[(3R)-3-AMINOPIPERIDIN-1-YL]-3-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL}METHYL)BENZONITRILE3g0bBY666
T222-({6-[(3R)-3-AMINOPIPERIDIN-1-YL]-3-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL}METHYL)BENZONITRILE3g0bCY666
T222-({6-[(3R)-3-AMINOPIPERIDIN-1-YL]-3-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL}METHYL)BENZONITRILE3g0bDY666
RUF7-(2-CHLOROBENZYL)-1,3-DIMETHYL-8-PIPERAZIN-1-YL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE3g0cAY666
RUF7-(2-CHLOROBENZYL)-1,3-DIMETHYL-8-PIPERAZIN-1-YL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE3g0cBY666
RUF7-(2-CHLOROBENZYL)-1,3-DIMETHYL-8-PIPERAZIN-1-YL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE3g0cCY666
RUF7-(2-CHLOROBENZYL)-1,3-DIMETHYL-8-PIPERAZIN-1-YL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE3g0cDY666
XIH2-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILE3g0dAY666
XIH2-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILE3g0dBY666
XIH2-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILE3g0dCY666
XIH2-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILE3g0dDY666
RUM2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-5-BROMO-6-OXOPYRIMIDIN-1(6H)-YL}METHYL)BENZONITRILE3g0gAY666
RUM2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-5-BROMO-6-OXOPYRIMIDIN-1(6H)-YL}METHYL)BENZONITRILE3g0gBY666
RUM2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-5-BROMO-6-OXOPYRIMIDIN-1(6H)-YL}METHYL)BENZONITRILE3g0gCY666
RUM2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-5-BROMO-6-OXOPYRIMIDIN-1(6H)-YL}METHYL)BENZONITRILE3g0gDY666
PS4N-({(2S)-1-[(3R)-3-AMINO-4-(3-CHLOROPHENYL)BUTANOYL]PYRROLIDIN-2-YL}METHYL)-3-(METHYLSULFONYL)BENZAMIDE3h0cAY666
PS4N-({(2S)-1-[(3R)-3-AMINO-4-(3-CHLOROPHENYL)BUTANOYL]PYRROLIDIN-2-YL}METHYL)-3-(METHYLSULFONYL)BENZAMIDE3h0cBY666
677(2R,3R)-7-(METHYLSULFONYL)-3-(2,4,5-TRIFLUOROPHENYL)-1,2,3,4-TETRAHYDROPYRIDO[1,2-A]BENZIMIDAZOL-2-AMINE3habAY666
677(2R,3R)-7-(METHYLSULFONYL)-3-(2,4,5-TRIFLUOROPHENYL)-1,2,3,4-TETRAHYDROPYRIDO[1,2-A]BENZIMIDAZOL-2-AMINE3habBY666
361(7R,8R)-8-(2,4,5-TRIFLUOROPHENYL)-6,7,8,9-TETRAHYDROIMIDAZO[1,2-A:4,5-C']DIPYRIDIN-7-AMINE3hacAY666
361(7R,8R)-8-(2,4,5-TRIFLUOROPHENYL)-6,7,8,9-TETRAHYDROIMIDAZO[1,2-A:4,5-C']DIPYRIDIN-7-AMINE3hacBY666
B1Q(4S)-1-[(2S,3S,11BS)-2-AMINO-9,10-DIMETHOXY-1,3,4,6,7,11B-HEXAHYDRO-2H-PYRIDO[2,1-A]ISOQUINOLIN-3-YL]-4-(FLUOROMETHYL)PYRROLIDIN-2-ONE3kwfAY666
B1Q(4S)-1-[(2S,3S,11BS)-2-AMINO-9,10-DIMETHOXY-1,3,4,6,7,11B-HEXAHYDRO-2H-PYRIDO[2,1-A]ISOQUINOLIN-3-YL]-4-(FLUOROMETHYL)PYRROLIDIN-2-ONE3kwfBY666
23Q(2S,3S,11BS)-3-[3-(FLUOROMETHYL)PHENYL]-9,10-DIMETHOXY-1,3,4,6,7,11B-HEXAHYDRO-2H-PYRIDO[2,1-A]ISOQUINOLIN-2-AMINE3kwjAY666
23Q(2S,3S,11BS)-3-[3-(FLUOROMETHYL)PHENYL]-9,10-DIMETHOXY-1,3,4,6,7,11B-HEXAHYDRO-2H-PYRIDO[2,1-A]ISOQUINOLIN-2-AMINE3kwjBY666
6A5SA-(+)-(6-(AMINOMETHYL)-5-(2,4-DICHLOROPHENYL)-7-METHYLIMIDAZO[1,2-A]PYRIMIDIN-2-YL)(MORPHOLINO)METHANONE3noxAY666
6A5SA-(+)-(6-(AMINOMETHYL)-5-(2,4-DICHLOROPHENYL)-7-METHYLIMIDAZO[1,2-A]PYRIMIDIN-2-YL)(MORPHOLINO)METHANONE3noxBY666
01T[5-(AMINOMETHYL)-6-(2,2-DIMETHYLPROPYL)-2-ETHYL-4-(4-METHYLPHENYL)PYRIDIN-3-YL]ACETIC ACID3o95AY666
01T[5-(AMINOMETHYL)-6-(2,2-DIMETHYLPROPYL)-2-ETHYL-4-(4-METHYLPHENYL)PYRIDIN-3-YL]ACETIC ACID3o95BY666
01T[5-(AMINOMETHYL)-6-(2,2-DIMETHYLPROPYL)-2-ETHYL-4-(4-METHYLPHENYL)PYRIDIN-3-YL]ACETIC ACID3o95CY666
01T[5-(AMINOMETHYL)-6-(2,2-DIMETHYLPROPYL)-2-ETHYL-4-(4-METHYLPHENYL)PYRIDIN-3-YL]ACETIC ACID3o95DY666
10T5-(AMINOMETHYL)-2-METHYL-4-(4-METHYLPHENYL)-6-(2-METHYLPROPYL)PYRIDINE-3-CARBOXIC ACID3o9vAY666
10T5-(AMINOMETHYL)-2-METHYL-4-(4-METHYLPHENYL)-6-(2-METHYLPROPYL)PYRIDINE-3-CARBOXIC ACID3o9vBY666
10T5-(AMINOMETHYL)-2-METHYL-4-(4-METHYLPHENYL)-6-(2-METHYLPROPYL)PYRIDINE-3-CARBOXIC ACID3o9vCY666
10T5-(AMINOMETHYL)-2-METHYL-4-(4-METHYLPHENYL)-6-(2-METHYLPROPYL)PYRIDINE-3-CARBOXIC ACID3o9vDY666
B2Q(2S,3R,11BR)-3-BUTYL-9,10-DIMETHOXY-1,3,4,6,7,11B-HEXAHYDRO-2H-PYRIDO[2,1-A]ISOQUINOLIN-2-AMINE3oc0BY666
LUI2-{[3-(AMINOMETHYL)-2-(2-METHYLPROPYL)-1-OXO-4-PHENYL-1,2-DIHYDROISOQUINOLIN-6-YL]OXY}ACETAMIDE3opmAY666
LUI2-{[3-(AMINOMETHYL)-2-(2-METHYLPROPYL)-1-OXO-4-PHENYL-1,2-DIHYDROISOQUINOLIN-6-YL]OXY}ACETAMIDE3opmBY666
LUI2-{[3-(AMINOMETHYL)-2-(2-METHYLPROPYL)-1-OXO-4-PHENYL-1,2-DIHYDROISOQUINOLIN-6-YL]OXY}ACETAMIDE3opmCY666
LUI2-{[3-(AMINOMETHYL)-2-(2-METHYLPROPYL)-1-OXO-4-PHENYL-1,2-DIHYDROISOQUINOLIN-6-YL]OXY}ACETAMIDE3opmDY666
LGEMETHYL [3-(AMINOMETHYL)-4-(2,4-DIMETHYLPHENYL)-2-METHYL-7-OXO-5,7-DIHYDRO-6H-PYRROLO[3,4-B]PYRIDIN-6-YL]ACETATE3q0tAY666
LGEMETHYL [3-(AMINOMETHYL)-4-(2,4-DIMETHYLPHENYL)-2-METHYL-7-OXO-5,7-DIHYDRO-6H-PYRROLO[3,4-B]PYRIDIN-6-YL]ACETATE3q0tBY666
AZVN-(4-{[({(2R)-3-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-1,3-THIAZOLIDIN-2-YL}CARBONYL)AMINO]METHYL}PHENYL)-D-VALINE3q8wAY666
AZVN-(4-{[({(2R)-3-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-1,3-THIAZOLIDIN-2-YL}CARBONYL)AMINO]METHYL}PHENYL)-D-VALINE3q8wBY666
NXZ1-[(3S,4S)-4-AMINO-1-(6-PHENYLPYRIMIDIN-4-YL)PYRROLIDIN-3-YL]PIPERIDIN-2-ONE3qbjAY666
NXZ1-[(3S,4S)-4-AMINO-1-(6-PHENYLPYRIMIDIN-4-YL)PYRROLIDIN-3-YL]PIPERIDIN-2-ONE3qbjBY666
KXB3-(AMINOMETHYL)-4-(2,4-DICHLOROPHENYL)-6-(2-METHOXYETHYL)-2-METHYL-5,6-DIHYDRO-7H-PYRROLO[3,4-B]PYRIDIN-7-ONE3swwAY666
KXB3-(AMINOMETHYL)-4-(2,4-DICHLOROPHENYL)-6-(2-METHOXYETHYL)-2-METHYL-5,6-DIHYDRO-7H-PYRROLO[3,4-B]PYRIDIN-7-ONE3swwBY666
KXA3-(AMINOMETHYL)-4-(2,4-DICHLOROPHENYL)-6-(2-METHOXYPHENYL)-2-METHYL-5,6-DIHYDRO-7H-PYRROLO[3,4-B]PYRIDIN-7-ONE3sx4AY666
KXA3-(AMINOMETHYL)-4-(2,4-DICHLOROPHENYL)-6-(2-METHOXYPHENYL)-2-METHYL-5,6-DIHYDRO-7H-PYRROLO[3,4-B]PYRIDIN-7-ONE3sx4BY666
M51{(2S,4S)-4-[4-(3-METHYL-1-PHENYL-1H-PYRAZOL-5-YL) PIPERAZIN-1-YL]PYRROLIDIN-2-YL}(1,3-THIAZOLIDIN-3-YL) METHANONE3vjkAY666
M51{(2S,4S)-4-[4-(3-METHYL-1-PHENYL-1H-PYRAZOL-5-YL) PIPERAZIN-1-YL]PYRROLIDIN-2-YL}(1,3-THIAZOLIDIN-3-YL) METHANONE3vjkBY666
W94[(2S,4S)-4-{4-[1-PHENYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOL- 5-YL]PIPERIDIN-1-YL}PYRROLIDIN-2-YL](1,3-THIAZOLIDIN- 3-YL)METHANONE3vjlAY666
W94[(2S,4S)-4-{4-[1-PHENYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOL- 5-YL]PIPERIDIN-1-YL}PYRROLIDIN-2-YL](1,3-THIAZOLIDIN- 3-YL)METHANONE3vjlBY666
D1C4-[({[(2R)-2-AMINO-3-(2,4,5-TRIFLUOROPHENYL) PROPYL]SULFAMOYL}AMINO)METHYL]BENZENESULFONAMIDE4dsaAY666
DC3(2R)-4-[4-(3-METHYLPHENYL)-1H-1,2,3-TRIAZOL-1-YL]-1-(2, 4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE4dszAY666
DC3(2R)-4-[4-(3-METHYLPHENYL)-1H-1,2,3-TRIAZOL-1-YL]-1-(2, 4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE4dszBY666
D5CN-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTYL]-3'- (TRIFLUOROMETHYL)BIPHENYL-4-CARBOXAMIDE4dtcAY666
0WG7-AMINO-6-(AMINOMETHYL)-5-(2-BROMOPHENYL)-1,3- DIMETHYLPYRIDO[2,3-D]PYRIMIDINE-2,4(1H,3H)-DIONE4g1fAY666
0WG7-AMINO-6-(AMINOMETHYL)-5-(2-BROMOPHENYL)-1,3- DIMETHYLPYRIDO[2,3-D]PYRIMIDINE-2,4(1H,3H)-DIONE4g1fBY666
0WG7-AMINO-6-(AMINOMETHYL)-5-(2-BROMOPHENYL)-1,3- DIMETHYLPYRIDO[2,3-D]PYRIMIDINE-2,4(1H,3H)-DIONE4g1fCY666
0WG7-AMINO-6-(AMINOMETHYL)-5-(2-BROMOPHENYL)-1,3- DIMETHYLPYRIDO[2,3-D]PYRIMIDINE-2,4(1H,3H)-DIONE4g1fDY666
LF7VILDAGLIPTIN(2S)-1-{N-[(1R,3S,5R,7S)-3-HYDROXYTRICYCLO[3.3.1.1~3, 7~]DEC-1-YL]GLYCYL}PYRROLIDINE-2-CARBONITRILE3w2tAY666
LF7VILDAGLIPTIN(2S)-1-{N-[(1R,3S,5R,7S)-3-HYDROXYTRICYCLO[3.3.1.1~3, 7~]DEC-1-YL]GLYCYL}PYRROLIDINE-2-CARBONITRILE3w2tBY666
1MD2-[3-(AMINOMETHYL)-4-(2,4-DICHLOROPHENYL)-2-METHYL-5- OXO-5,7-DIHYDRO-6H-PYRROLO[3,4-B]PYRIDIN-6-YL]-N,N- DIMETHYLACETAMIDE4jh0AY666
1MD2-[3-(AMINOMETHYL)-4-(2,4-DICHLOROPHENYL)-2-METHYL-5- OXO-5,7-DIHYDRO-6H-PYRROLO[3,4-B]PYRIDIN-6-YL]-N,N- DIMETHYLACETAMIDE4jh0BY666
1WH3-(AMINOMETHYL)-4-(2,4-DICHLOROPHENYL)-6-(2- METHOXYETHYL)-2-METHYL-6,7-DIHYDRO-5H-PYRROLO[3,4- B]PYRIDIN-5-ONE4lkoAY666
1WH3-(AMINOMETHYL)-4-(2,4-DICHLOROPHENYL)-6-(2- METHOXYETHYL)-2-METHYL-6,7-DIHYDRO-5H-PYRROLO[3,4- B]PYRIDIN-5-ONE4lkoBY666
2KS1-(CIS-1-PHENYL-4-{[(2E)-3-PHENYLPROP-2-EN-1- YL]OXY}CYCLOHEXYL)METHANAMINE4n8dAY666
2KS1-(CIS-1-PHENYL-4-{[(2E)-3-PHENYLPROP-2-EN-1- YL]OXY}CYCLOHEXYL)METHANAMINE4n8dBY666
2KV1-[CIS-4-(AMINOMETHYL)-4-(3-CHLOROPHENYL) CYCLOHEXYL]PIPERIDIN-2-ONE4n8eAY666
2KV1-[CIS-4-(AMINOMETHYL)-4-(3-CHLOROPHENYL) CYCLOHEXYL]PIPERIDIN-2-ONE4n8eBY666
2VH(2R,3S,5R)-5-[2-(METHYLSULFONYL)-2,6-DIHYDROPYRROLO[3, 4-C]PYRAZOL-5(4H)-YL]-2-(2,4,5-TRIFLUOROPHENYL) TETRAHYDRO-2H-PYRAN-3-AMINE4pnzAY666
2VH(2R,3S,5R)-5-[2-(METHYLSULFONYL)-2,6-DIHYDROPYRROLO[3, 4-C]PYRAZOL-5(4H)-YL]-2-(2,4,5-TRIFLUOROPHENYL) TETRAHYDRO-2H-PYRAN-3-AMINE4pnzBY666
CJP1-[2-(2,4-DICHLOROPHENYL)-1-(METHYLSULFONYL)-1H-INDOL- 3-YL]METHANAMINE4pv7AY666
CJP1-[2-(2,4-DICHLOROPHENYL)-1-(METHYLSULFONYL)-1H-INDOL- 3-YL]METHANAMINE4pv7BY666
IIIPeptide ligand (TYR,PRO,SER,LYS)1r9nAY666 G741
IIIPeptide ligand (TYR,PRO,SER,LYS,PRO,ASP)1r9nBY666 G741
IIIPeptide ligand (TYR,PRO,SER,LYS)1r9nCY666 G741
IIIPeptide ligand (TYR,PRO,SER,LYS,PRO)1r9nDY666 G741
IIIPeptide ligand (MET,TRP,PRO,VAL,ASP,PRO)2bgnBY666 H748


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Conservation information for LBS of DPP4
Multiple alignments for P27487 in multiple species
LBSAA sequence# speciesSpecies
D192WTGKEDIIYNG1Homo sapiens
D192VGGSTFNRF-G1Caenorhabditis elegans
D192STGEENVIYNG1Mus musculus
D192STGKENVIFNG1Rattus norvegicus
D192YDGTVD-VFNG1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
D192NDGSSF-LFNG1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
D192KDGGAD-LFYG1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
D274FVVNTDSLSSV1Homo sapiens
D274YIWDSENHKIV1Caenorhabditis elegans
D274FIVNIDSLSSS1Mus musculus
D274FIVNTDSLSST1Rattus norvegicus
D274FVADLNSNASS1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
D274WVYSMKDGTSF1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
D274QFYDIARGDVF1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
D545YPLLLDVYAGP2Homo sapiens, Mus musculus
D545IPLLLDIYGGP1Caenorhabditis elegans
D545YPLLIDVYAGP1Rattus norvegicus
D545YPVLFFAYGGP1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
D545YPVFFFAYGGP1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
D545YPVLFHQYSGP1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
D605TLEVEDQIEAA2Mus musculus, Rattus norvegicus
D605TFEVEDQIEAA1Homo sapiens
D605DAEVVDTLDMI1Caenorhabditis elegans
D605EWESYDQGQAG1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
D605DYEARDQISAA1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
D605EIEAQDQIAAA1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
D681PEDNLDHYRNS3Homo sapiens, Mus musculus, Rattus norvegicus
D681PAENLQGYINT1Caenorhabditis elegans
D681PQYNKEGYKNS1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
D681PQENFDGYVES1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
D681PQQNEDGYTKS1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
E191TWTGKEDIIYN1Homo sapiens
E191TVGGSTFNRF-1Caenorhabditis elegans
E191TSTGEENVIYN1Mus musculus
E191TSTGKENVIFN1Rattus norvegicus
E191TYDGTVD-VFN1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
E191TNDGSSF-LFN1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
E191TKDGGAD-LFY1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
E205DWVYEEEVFSA1Homo sapiens
E205NWLYEEEILEA1Caenorhabditis elegans
E205DWVYEEEVFGA1Mus musculus
E205DWVYEEEIFGA1Rattus norvegicus
E205DWIYEEEVLSS1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
E205DWVYEEEVFED1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
E205DWVYEEEVIAG1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
E206WVYEEEVFSAY1Homo sapiens
E206WLYEEEILEAS1Caenorhabditis elegans
E206WVYEEEVFGAY1Mus musculus
E206WVYEEEIFGAY1Rattus norvegicus
E206WIYEEEVLSSP1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
E206WVYEEEVFEDD1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
E206WVYEEEVIAGA1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
E232QFNDTGVPLIE2Mus musculus, Rattus norvegicus
E232QFNDTEVPLIE1Homo sapiens
E232RFDDREVNRIF1Caenorhabditis elegans
E232KLNESEIPTYH1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
E232KIDESEVGEFI1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
E232RTNETGVPAFP1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
E309---TQERISLQ1Homo sapiens
E309SDLGEERLVTV1Caenorhabditis elegans
E309---TEERISLQ1Mus musculus
E309---SEDRISLQ1Rattus norvegicus
E309---NTSSVLVQ1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
E309---GNGNVLVK1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
E309---GS-QVIVK1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
E332ICDYDESSGRW1Homo sapiens
E332LCNEQDCVMA-1Caenorhabditis elegans
E332ICDYDKINLTW1Mus musculus
E332ICDYDKTTLVW1Rattus norvegicus
E332LLDTELKSIH-1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
E332LIDTIAKTSN-1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
E332LIDVKKRTGK-1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
E361RFRPAEPH--F2Mus musculus, Rattus norvegicus
E361RFRPSEPH--F1Homo sapiens
E361GVFPTE-----1Caenorhabditis elegans
E361KMFPLNNSLVW1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
E361LFIPANET--F1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
E361KYIPADPK--K1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
E608VEDQIEAARQF3Homo sapiens, Mus musculus, Rattus norvegicus
E608VVDTLDMIRAF1Caenorhabditis elegans
E608SYDQGQAGKFW1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
E608ARDQISAASLY1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
E608AQDQIAAAKHW1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
E67-----EYLYKQ3Homo sapiens, Mus musculus, Rattus norvegicus
E67-----SFVQMN1Caenorhabditis elegans
E67-----TFLVKY1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
E67G----LYVTFM1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
E67GADGKDYIVIE1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
E73YLYKQE-----3Homo sapiens, Mus musculus, Rattus norvegicus
E73FVQMND--DFT1Caenorhabditis elegans
E73FLVKYG-----1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
E73YVTFMN-----1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
E73YIVIEDGRAEN1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
F222SPNGTFLAYAQ2Homo sapiens, Rattus norvegicus
F222SPSGRYVSYLR1Caenorhabditis elegans
F222SPNNTFLAYAQ1Mus musculus
F222SPDSDKIAFLK1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
F222SPTGDYLAFLK1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
F222SEDGKYVAFLR1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
F240LIEYSFYS---3Homo sapiens, Mus musculus, Rattus norvegicus
F240RIFLPKYT---1Caenorhabditis elegans
F240TYHYPLYT---1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
F240EFIIPYYV---1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
F240AFPVQYFMSRP1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
F357----RFRPAEP2Mus musculus, Rattus norvegicus
F357----RFRPSEP1Homo sapiens
F357KDVRGVFPTE-1Caenorhabditis elegans
F357QQSAKMFPLNN1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
F357THNTLFIPANE1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
F357SQNTKYIPADP1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
F524-NETRF-----2Mus musculus, Rattus norvegicus
F524-NETKF-----1Homo sapiens
F524PSGIDG-----1Caenorhabditis elegans
F524-NDTTF-----1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
F524-GKDEFGKDIL1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
F524-EGVEL-----1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
G220WWSPNGTFLAY2Homo sapiens, Rattus norvegicus
G220WWSPSGRYVSY1Caenorhabditis elegans
G220WWSPNNTFLAY1Mus musculus
G220WWSPDSDKIAF1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
G220WWSPTGDYLAF1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
G220WWSEDGKYVAF1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
G628RIAIWGWSYGG2Homo sapiens, Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
G628RVAIWGWSYGG2Mus musculus, Rattus norvegicus
G628RIAVMGWSYGG1Caenorhabditis elegans
G628HVGIWGWSYGG1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
G628KISLFGWSYGG1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
G741TDEDHGIASST3Homo sapiens, Mus musculus, Rattus norvegicus
G741ANEAHSLSHKL1Caenorhabditis elegans
G741PDSAHSISYHN1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
G741PDSDHSIRYHN1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
G741PDSDHSIFFHN1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
H126VKQWRHSYTAS3Homo sapiens, Mus musculus, Rattus norvegicus
H126NELWRHSAEYL1Caenorhabditis elegans
H126SQRWRHSSFAQ1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
H126VQNWRHSTFGS1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
H126KSNWRHSHTAC1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
H740YTDEDHGIASS3Homo sapiens, Mus musculus, Rattus norvegicus
H740YANEAHSLSHK1Caenorhabditis elegans
H740FPDSAHSISYH1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
H740FPDSDHSIRYH1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
H740FPDSDHSIFFH1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
H748ASSTAHQHIYS2Mus musculus, Rattus norvegicus
H748ASSTAHQHIYT1Homo sapiens
H748SHKL--FHLYG1Caenorhabditis elegans
H748SYHNASLSIYH1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
H748RYHNANVIVFD1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
H748FFHNANKIIYD1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
I148TEE-KIPNNTQ2Mus musculus, Rattus norvegicus
I148TEE-RIPNNTQ1Homo sapiens
I148TEQWHVGPEEN1Caenorhabditis elegans
I148-NM-LGQDNEH1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
I148-EE--IGNE--1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
I148-EP-LIPASPD1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
I194GKEDIIYNGIT1Homo sapiens
I194GSTFNRF-GLA1Caenorhabditis elegans
I194GEENVIYNGIT1Mus musculus
I194GKENVIFNGIN1Rattus norvegicus
I194GTVD-VFNGLT1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
I194GSSF-LFNGKP1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
I194GGAD-LFYGVP1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
I319QWLRRIQNYSV3Homo sapiens, Mus musculus, Rattus norvegicus
I319VWANRDQNHVY1Caenorhabditis elegans
I319QFTNRNSTCIT1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
I319KTTDRSSDILT1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
I319KETNRVSDIMR1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
K250SLQYPKTVWIP2Mus musculus, Rattus norvegicus
K250SLQYPKTVRVP1Homo sapiens
K250DDSYVEYFELP1Caenorhabditis elegans
K250EFDYNKDMAIK1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
K250KDIYPEMRSIK1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
K250EETYPEVRDIK1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
K267NPT-VKFFIVN2Mus musculus, Rattus norvegicus
K267NPT-VKFFVVN1Homo sapiens
K267NNTLVTQYIWD1Caenorhabditis elegans
K267NPS-VSLFVAD1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
K267NPH-AELWVYS1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
K267NPV-VDVQFYD1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
K554GPCSQKADTVF1Homo sapiens
K554GPDSKQVFQKT1Caenorhabditis elegans
K554GPCSQKADASF1Mus musculus
K554GPCSQKADAAF1Rattus norvegicus
K554GPGSQQVAKLF1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
K554GPNSQQVVKTF1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
K554GPGSQSVSQKF1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
L519LDFIVL-NETR2Mus musculus, Rattus norvegicus
L519LDFIIL-NETK1Homo sapiens
L519FGKLKLPSGID1Caenorhabditis elegans
L519YGKLTF-NDTT1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
L519FRELNL-GKDE1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
L519YGTLNV-EGVE1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
M348RQHIEMSTTGW1Homo sapiens
M348QFSIDNRQL-W1Caenorhabditis elegans
M348QQHVEMSTTGW1Mus musculus
M348QEHIETSATGW1Rattus norvegicus
M348T---ECLEEGW1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
M348N---ESSNGGW1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
M348TVDVGKIDGGW1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
N150E-KIPNNTQW-2Mus musculus, Rattus norvegicus
N150E-RIPNNTQW-1Homo sapiens
N150QWHVGPEENSL1Caenorhabditis elegans
N150M-LGQDNEHWT1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
N150E--IGNE----1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
N150P-LIPASPDAR1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
N219LWWSPNGTFLA2Homo sapiens, Rattus norvegicus
N219VWWSPSGRYVS1Caenorhabditis elegans
N219LWWSPNNTFLA1Mus musculus
N219IWWSPDSDKIA1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
N219AWWSPTGDYLA1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
N219TWWSEDGKYVA1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
N229AYAQFNDTGVP2Mus musculus, Rattus norvegicus
N229AYAQFNDTEVP1Homo sapiens
N229SYLRFDDREVN1Caenorhabditis elegans
N229AFLKLNESEIP1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
N229AFLKIDESEVG1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
N229AFLRTNETGVP1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
N272KFFVVNTDSLS1Homo sapiens
N272TQYIWDSENHK1Caenorhabditis elegans
N272KFFIVNIDSLS1Mus musculus
N272KFFIVNTDSLS1Rattus norvegicus
N272SLFVADLNSNA1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
N272ELWVYSMKDGT1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
N272DVQFYDIARGD1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
N281LSSVTNATSIQ1Homo sapiens
N281HKIVETAPPNE1Caenorhabditis elegans
N281LSSSSSAAPIQ1Mus musculus
N281LSSTTTTIPMQ1Rattus norvegicus
N281NASSNFSLWHN1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
N281GTSFHPRISGN1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
N281GDVFTVDINGG1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
N321LRRIQNYSVMA2Mus musculus, Rattus norvegicus
N321LRRIQNYSVMD1Homo sapiens
N321ANRDQNHVYFS1Caenorhabditis elegans
N321TNRNSTCITAR1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
N321TDRSSDILTVF1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
N321TNRVSDIMRVV1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
N520FIVL-NETRF-2Mus musculus, Rattus norvegicus
N520FIIL-NETKF-1Homo sapiens
N520KLKLPSGIDG-1Caenorhabditis elegans
N520KLTF-NDTTF-1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
N520ELNL-GKDEFG1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
N520TLNV-EGVEL-1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
N685LDHYRNSTVMS3Homo sapiens, Mus musculus, Rattus norvegicus
N685LQGYINTNVIP1Caenorhabditis elegans
N685KEGYKNSQIHD1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
N685FDGYVESSVHN1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
N685EDGYTKSAVHN1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
N710GTADDNVHFQQ3Homo sapiens, Mus musculus, Rattus norvegicus
N710GERDDNVHYQN1Caenorhabditis elegans
N710GTGDDNVHFQH1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
N710GTGDDNVHFQN1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
N710GASDDNVHFQN1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
N74-----NNILVF1Homo sapiens
N74DFTIRKQMKKI1Caenorhabditis elegans
N74-----NNILLL1Mus musculus
N74-----NNILLF1Rattus norvegicus
N74------DLINI1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
N74----DSYVVKS1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
N74AENPDSSAEAE1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
N75----NNILVFN1Homo sapiens
N75FTIRKQMKKIP1Caenorhabditis elegans
N75----NNILLLN1Mus musculus
N75----NNILLFN1Rattus norvegicus
N75-----DLINIQ1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
N75---DSYVVKSV1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
N75ENPDSSAEAEV1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
N80NILVFNAEYGN1Homo sapiens
N80QMKKIPLGSSV1Caenorhabditis elegans
N80NILLLNAEHGN1Mus musculus
N80NILLFNAEHGN1Rattus norvegicus
N80DLINIQDPYNL1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
N80YVVKSVYDDSY1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
N80SAEAEVDVTAS1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
N85NAEHGNSSIFL2Mus musculus, Rattus norvegicus
N85NAEYGNSSVFL1Homo sapiens
N85PLGSSVAEPFF1Caenorhabditis elegans
N85QDPYNLNKTLF1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
N85VYDDSYNSVLL1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
N85VDVTASRRTLM1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
N92SVFLENSTFDE1Homo sapiens
N92EPFFNNGEYVK1Caenorhabditis elegans
N92SIFLENSTFES1Mus musculus
N92SIFLENSTFEI1Rattus norvegicus
N92KTLFSVSDLVY1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
N92SVLLEGKTFIH1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
N92RTLMKNGSFRY1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
P359--RFRPAEPH-2Mus musculus, Rattus norvegicus
P359--RFRPSEPH-1Homo sapiens
P359VRGVFPTE---1Caenorhabditis elegans
P359SAKMFPLNNSL1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P359NTLFIPANET-1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P359NTKYIPADPK-1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
P550DVYAGPCSQKA3Homo sapiens, Mus musculus, Rattus norvegicus
P550DIYGGPDSKQV1Caenorhabditis elegans
P550FAYGGPGSQQV1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P550FAYGGPNSQQV1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P550HQYSGPGSQSV1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
Q123YNYVKQWRHSY3Homo sapiens, Mus musculus, Rattus norvegicus
Q123KKVNELWRHSA1Caenorhabditis elegans
Q123VNKSQRWRHSS1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q123TNSVQNWRHST1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q123TEQKSNWRHSH1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
Q308----TQERISL1Homo sapiens
Q308GSDLGEERLVT1Caenorhabditis elegans
Q308----TEERISL1Mus musculus
Q308----SEDRISL1Rattus norvegicus
Q308----NTSSVLV1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q308----GNGNVLV1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q308----GS-QVIV1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
Q553AGPCSQKADTV1Homo sapiens
Q553GGPDSKQVFQK1Caenorhabditis elegans
Q553AGPCSQKADAS1Mus musculus
Q553AGPCSQKADAA1Rattus norvegicus
Q553GGPGSQQVAKL1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q553GGPNSQQVVKT1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q553SGPGSQSVSQK1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
R125YVKQWRHSYTA3Homo sapiens, Mus musculus, Rattus norvegicus
R125VNELWRHSAEY1Caenorhabditis elegans
R125KSQRWRHSSFA1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
R125SVQNWRHSTFG1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
R125QKSNWRHSHTA1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
R147ITEE-KIPNNT2Mus musculus, Rattus norvegicus
R147ITEE-RIPNNT1Homo sapiens
R147STEQWHVGPEE1Caenorhabditis elegans
R147--NM-LGQDNE1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
R147--EE--IGNE-1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
R147--EP-LIPASP1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
R253YPKTVWIPYPK2Mus musculus, Rattus norvegicus
R253YPKTVRVPYPK1Homo sapiens
R253YVEYFELPYPK1Caenorhabditis elegans
R253YNKDMAIKYPK1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
R253YPEMRSIKYPK1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
R253YPEVRDIKYPR1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
R317SLQWLRRIQNY3Homo sapiens, Mus musculus, Rattus norvegicus
R317VTVWANRDQNH1Caenorhabditis elegans
R317LVQFTNRNSTC1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
R317LVKTTDRSSDI1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
R317IVKETNRVSDI1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
R356-----RFRPAE2Mus musculus, Rattus norvegicus
R356-----RFRPSE1Homo sapiens
R356PKDVRGVFPTE1Caenorhabditis elegans
R356VQQSAKMFPLN1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
R356ITHNTLFIPAN1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
R356ISQNTKYIPAD1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
R358---RFRPAEPH2Mus musculus, Rattus norvegicus
R358---RFRPSEPH1Homo sapiens
R358DVRGVFPTE--1Caenorhabditis elegans
R358QSAKMFPLNNS1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
R358HNTLFIPANET1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
R358QNTKYIPADPK1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
R581ASFDGRGSGYQ3Homo sapiens, Mus musculus, Rattus norvegicus
R581ARIDVRGTGGR1Caenorhabditis elegans
R581VTLDGRGTGFN1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
R581VVVDGRGTGFK1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
R581VTFDGRGTGFI1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
R596MHAINRRLGTF1Homo sapiens
R596KEAVYRKLGDA1Caenorhabditis elegans
R596MHAINRRLGTL1Mus musculus
R596MHAINKRLGTL1Rattus norvegicus
R596RYSVSRHLGEW1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
R596RSLVRDRLGDY1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
R596RVLVRSRLGEI1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
R684NLDHYRNSTVM3Homo sapiens, Mus musculus, Rattus norvegicus
R684NLQGYINTNVI1Caenorhabditis elegans
R684NKEGYKNSQIH1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
R684NFDGYVESSVH1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
R684NEDGYTKSAVH1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
S209EEEVFSAYSAL1Homo sapiens
S209EEEILEASSAV1Caenorhabditis elegans
S209EEEVFGAYSAL1Mus musculus
S209EEEIFGAYSAL1Rattus norvegicus
S209EEEVLSSPSTI1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
S209EEEVFEDDKAA1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
S209EEEVIAGASTT1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
S349QHIEMSTTGWV1Homo sapiens
S349FSIDNRQL-WV1Caenorhabditis elegans
S349QHVEMSTTGWV1Mus musculus
S349EHIETSATGWC1Rattus norvegicus
S349---ECLEEGWY1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
S349---ESSNGGWW1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
S349VDVGKIDGGWF1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
S360-RFRPAEPH--2Mus musculus, Rattus norvegicus
S360-RFRPSEPH--1Homo sapiens
S360RGVFPTE----1Caenorhabditis elegans
S360AKMFPLNNSLV1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
S360TLFIPANET--1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
S360TKYIPADPK--1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
S552YAGPCSQKADA2Mus musculus, Rattus norvegicus
S552YAGPCSQKADT1Homo sapiens
S552YGGPDSKQVFQ1Caenorhabditis elegans
S552YGGPGSQQVAK1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
S552YGGPNSQQVVK1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
S552YSGPGSQSVSQ1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
S630AIWGWSYGGYV3Homo sapiens, Mus musculus, Rattus norvegicus
S630AVMGWSYGGFL1Caenorhabditis elegans
S630GIWGWSYGGYL1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
S630SLFGWSYGGYL1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
S630AIWGWSYGGFQ1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
S86AEHGNSSIFLE2Mus musculus, Rattus norvegicus
S86AEYGNSSVFLE1Homo sapiens
S86LGSSVAEPFFN1Caenorhabditis elegans
S86DPYNLNKTLFS1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
S86YDDSYNSVLLE1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
S86DVTASRRTLMK1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
S87EHGNSSIFLEN2Mus musculus, Rattus norvegicus
S87EYGNSSVFLEN1Homo sapiens
S87GSSVAEPFFNN1Caenorhabditis elegans
S87PYNLNKTLFSV1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
S87DDSYNSVLLEG1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
S87VTASRRTLMKN1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
T221WSPNGTFLAYA2Homo sapiens, Rattus norvegicus
T221WSPSGRYVSYL1Caenorhabditis elegans
T221WSPNNTFLAYA1Mus musculus
T221WSPDSDKIAFL1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
T221WSPTGDYLAFL1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
T221WSEDGKYVAFL1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
T231AQFNDTGVPLI2Mus musculus, Rattus norvegicus
T231AQFNDTEVPLI1Homo sapiens
T231LRFDDREVNRI1Caenorhabditis elegans
T231LKLNESEIPTY1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
T231LKIDESEVGEF1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
T231LRTNETGVPAF1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
T251LQYPKTVWIPY2Mus musculus, Rattus norvegicus
T251LQYPKTVRVPY1Homo sapiens
T251DSYVEYFELPY1Caenorhabditis elegans
T251FDYNKDMAIKY1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
T251DIYPEMRSIKY1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
T251ETYPEVRDIKY1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
T350HIEMSTTGWVG1Homo sapiens
T350SIDNRQL-WVS1Caenorhabditis elegans
T350HVEMSTTGWVG1Mus musculus
T350HIETSATGWCG1Rattus norvegicus
T350--ECLEEGWYE1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
T350--ESSNGGWWE1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
T350DVGKIDGGWFE1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
V207VYEEEVFSAYS1Homo sapiens
V207LYEEEILEASS1Caenorhabditis elegans
V207VYEEEVFGAYS1Mus musculus
V207VYEEEIFGAYS1Rattus norvegicus
V207IYEEEVLSSPS1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
V207VYEEEVFEDDK1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
V207VYEEEVIAGAS1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
V252QYPKTVWIPYP2Mus musculus, Rattus norvegicus
V252QYPKTVRVPYP1Homo sapiens
V252SYVEYFELPYP1Caenorhabditis elegans
V252DYNKDMAIKYP1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
V252IYPEMRSIKYP1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
V252TYPEVRDIKYP1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
V254PKTVWIPYPKA2Mus musculus, Rattus norvegicus
V254PKTVRVPYPKA1Homo sapiens
V254VEYFELPYPKA1Caenorhabditis elegans
V254NKDMAIKYPKP1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
V254PEMRSIKYPKS1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
V254PEVRDIKYPRS1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
V279DSLSSVTNATS1Homo sapiens
V279ENHKIVETAPP1Caenorhabditis elegans
V279DSLSSSSSAAP1Mus musculus
V279DSLSSTTTTIP1Rattus norvegicus
V279NSNASSNFSLW1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
V279KDGTSFHPRIS1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
V279ARGDVFTVDIN1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
V546PLLLDVYAGPC2Homo sapiens, Mus musculus
V546PLLLDIYGGPD1Caenorhabditis elegans
V546PLLIDVYAGPC1Rattus norvegicus
V546PVLFFAYGGPG1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
V546PVFFFAYGGPN1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
V546PVLFHQYSGPG1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
V656IAVAPVSRWEY3Homo sapiens, Mus musculus, Rattus norvegicus
V656ISIAPVTDFKY1Caenorhabditis elegans
V656MAVAPVTDWRL1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
V656MSVAPVTDWRF1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
V656MAVAPVTDWRF1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
V711TADDNVHFQQS3Homo sapiens, Mus musculus, Rattus norvegicus
V711ERDDNVHYQNS1Caenorhabditis elegans
V711TGDDNVHFQHS1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
V711TGDDNVHFQNS1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
V711ASDDNVHFQNS1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
V78-NNILVFNAEY1Homo sapiens
V78RKQMKKIPLGS1Caenorhabditis elegans
V78-NNILLLNAEH1Mus musculus
V78-NNILLFNAEH1Rattus norvegicus
V78--DLINIQDPY1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
V78DSYVVKSVYDD1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
V78DSSAEAEVDVT1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
W187SYRITWTGKED1Homo sapiens
W187AIQLTVGGSTF1Caenorhabditis elegans
W187SHRITSTGEEN1Mus musculus
W187SHRITSTGKEN1Rattus norvegicus
W187VQRLTYDGTVD1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
W187IRAVTNDGSSF1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
W187VTQITKDGGAD1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
W627KRVAIWGWSYG2Mus musculus, Rattus norvegicus
W627KRIAIWGWSYG1Homo sapiens
W627DRIAVMGWSYG1Caenorhabditis elegans
W627NHVGIWGWSYG1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
W627QKISLFGWSYG1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
W627SRIAIWGWSYG1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
W629VAIWGWSYGGY2Mus musculus, Rattus norvegicus
W629IAIWGWSYGGY1Homo sapiens
W629IAVMGWSYGGF1Caenorhabditis elegans
W629VGIWGWSYGGY1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
W629ISLFGWSYGGY1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
W629IAIWGWSYGGF1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
W659APVSRWEYYDS3Homo sapiens, Mus musculus, Rattus norvegicus
W659APVTDWRFYDS2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
W659APVTDFKYYDS1Caenorhabditis elegans
W659APVTDWRLYDS1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y322RRIQNYSVMAI2Mus musculus, Rattus norvegicus
Y322RRIQNYSVMDI1Homo sapiens
Y322NRDQNHVYFSL1Caenorhabditis elegans
Y322NRNSTCITARL1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y322DRSSDILTVFL1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y322NRVSDIMRVVL1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
Y330MDICDYDESSG1Homo sapiens
Y330FSLCNEQDCVM1Caenorhabditis elegans
Y330MAICDYDKINL1Mus musculus
Y330MAICDYDKTTL1Rattus norvegicus
Y330ARLLDTELKSI1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y330VFLIDTIAKTS1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y330VVLIDVKKRTG1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
Y48YTLTDYLKNT-1Homo sapiens
Y48PKFSSLMTTTR1Caenorhabditis elegans
Y48YSLADYLKST-1Mus musculus
Y48YTLADYLKNT-1Rattus norvegicus
Y48LSLDDIVLQK-1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y48VSFSVVRNNT-1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y48ITMDQVRSGT-1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
Y547LLLDVYAGPCS2Homo sapiens, Mus musculus
Y547LLLDIYGGPDS1Caenorhabditis elegans
Y547LLIDVYAGPCS1Rattus norvegicus
Y547VLFFAYGGPGS1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y547VFFFAYGGPNS1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y547VLFHQYSGPGS1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
Y585GRGSGYQGDKI3Homo sapiens, Mus musculus, Rattus norvegicus
Y585VRGTGGRGWDV1Caenorhabditis elegans
Y585GRGTGFNGNAF1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y585GRGTGFKGQDF1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y585GRGTGFIGRKN1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
Y631IWGWSYGGYVT3Homo sapiens, Mus musculus, Rattus norvegicus
Y631VMGWSYGGFLT1Caenorhabditis elegans
Y631IWGWSYGGYLT1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y631LFGWSYGGYLT1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y631IWGWSYGGFQT1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
Y662SRWEYYDSVYT3Homo sapiens, Mus musculus, Rattus norvegicus
Y662TDFKYYDSAYT1Caenorhabditis elegans
Y662TDWRLYDSVYT1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y662TDWRFYDSVYT1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y662TDWRFYDSIYT1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
Y666YYDSVYTERYM3Homo sapiens, Mus musculus, Rattus norvegicus
Y666YYDSAYTERYL1Caenorhabditis elegans
Y666LYDSVYTERYM1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y666FYDSVYTERYM1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y666FYDSIYTERYM1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
Y752AHQHIYSHMSH2Mus musculus, Rattus norvegicus
Y752AHQHIYTHMSH1Homo sapiens
Y752--FHLYGEVQR1Caenorhabditis elegans
Y752ASLSIYHRLSE1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y752ANVIVFDKLLD1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y752ANKIIYDKLEN1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
Y83VFNAEYGNSSV1Homo sapiens
Y83KIPLGSSVAEP1Caenorhabditis elegans
Y83LLNAEHGNSSI1Mus musculus
Y83LFNAEHGNSSI1Rattus norvegicus
Y83NIQDPYNLNKT1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Y83KSVYDDSYNSV1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Y83AEVDVTASRRT1Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)


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