mutLBSgeneDB

mutLBSgeneDB
mutated Ligand Binding Site gene DataBase

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Bioinformatics and Systems Medicine Laboratory Bioinformatics and Systems Medicine Laboratory

Gene Summary

Ligand Binding Site Mutation Information

Protein Structure Related Information

Gene Expression and Gene-Gene Network

Phenotype Information

Pharmacological Information

Conservation Information for LBS

Gene summary for PPP1CA
Gene summary
Basic gene Info.Gene symbolPPP1CA
Gene nameprotein phosphatase 1, catalytic subunit, alpha isozyme
SynonymsPP-1A|PP1A|PP1alpha|PPP1A
CytomapUCSC genome browser: 11q13
Type of geneprotein-coding
RefGenesNM_001008709.1,
NM_002708.3,NM_206873.1,
Descriptionprotein phosphatase 1, catalytic subunit, alpha isoformserine/threonine protein phosphatase PP1-alpha 1 catalytic subunitserine/threonine-protein phosphatase PP1-alpha catalytic subunit
Modification date20141222
dbXrefs MIM : 176875
HGNC : HGNC
Ensembl : ENSG00000172531
HPRD : 15942
Vega : OTTHUMG00000167671
ProteinUniProt: P62136
go to UniProt's Cross Reference DB Table
ExpressionCleanEX: HS_PPP1CA
BioGPS: 5499
PathwayNCI Pathway Interaction Database: PPP1CA
KEGG: PPP1CA
REACTOME: PPP1CA
Pathway Commons: PPP1CA
ContextiHOP: PPP1CA
ligand binding site mutation search in PubMed: PPP1CA
UCL Cancer Institute: PPP1CA
Assigned class in mutLBSgeneDBC: This gene just belongs to mutLBSgenes.

Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez
GO IDGO TermPubMed ID


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Ligand binding site mutations for PPP1CA

Cancer type specific mutLBS sorted by frequency
LBSAAchange of nsSNVCancer type# samples
E252D253NBLCA1
E252E252KBLCA1
D194D194NBLCA1
H125,C127E126DBLCA1
Y272Y272CCOAD1
R191R191WKIRC1
D220E218KSKCM1
D220D220YSKCM1
cf) Cancer type abbreviation. BLCA: Bladder urothelial carcinoma, BRCA: Breast invasive carcinoma, CESC: Cervical squamous cell carcinoma and endocervical adenocarcinoma, COAD: Colon adenocarcinoma, GBM: Glioblastoma multiforme, LGG: Brain lower grade glioma, HNSC: Head and neck squamous cell carcinoma, KICH: Kidney chromophobe, KIRC: Kidney renal clear cell carcinoma, KIRP: Kidney renal papillary cell carcinoma, LAML: Acute myeloid leukemia, LUAD: Lung adenocarcinoma, LUSC: Lung squamous cell carcinoma, OV: Ovarian serous cystadenocarcinoma, PAAD: Pancreatic adenocarcinoma, PRAD: Prostate adenocarcinoma, SKCM: Skin cutaneous melanoma, STAD: Stomach adenocarcinoma, THCA: Thyroid carcinoma, UCEC: Uterine corpus endometrial carcinoma.


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Protein structure related information for PPP1CA
Relative protein structure stability change (ΔΔE) using Mupro 1.1
Mupro score denotes assessment of the effect of mutations on thermodynamic stability.
  (ΔΔE<0: mutation decreases stability, ΔΔE>0: mutation increases stability)
: nsSNV at non-LBS: nsSNV at LBS

nsSNVs sorted by the relative stability change of protein structure by each mutation
Blue: mutations of positive stability change. and red : the most recurrent mutation for this gene.
LBSAAchange of nsSNVRelative stability change
E252E252K-1.3370199
R191R191W-1.0720855
D220E218K-1.0038007
C127E126D-0.98735419
H125E126D-0.98735419
Y272Y272C-0.98337604
D194D194N-0.97080544
E252D253N-0.6250307
D220D220Y-0.4530915
(MuPro1.1: Jianlin Cheng et al., Prediction of Protein Stability Changes for Single-Site Mutations Using Support Vector Machines, PROTEINS: Structure, Function, and Bioinformatics. 2006, 62:1125-1132)

Structure image for PPP1CA from PDB

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Differential gene expression and gene-gene network for PPP1CA
Differential gene expression between mutated and non-mutated LBS samples in all 16 major cancer types

Differential co-expressed gene network based on protein-protein interaction data (CePIN)
* Left PPI network was created from samples with mutations in the LBS of PPP1CA and the right PPI network was created from samples without mutations in the LBS of PPP1CA. Only genes with p-value < 0.05 are shown.
Red circle: input gene. Orange circle: LBSgene. Blue circle: other gene.


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Phenotype information for PPP1CA
Gene level disease information (DisGeNet)
Disease IDDisease name# PubMedAssociation type

Mutation level pathogenic information (ClinVar annotation)
Allele IDAA changeClinical significanceOriginPhenotype IDs

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Pharmacological information for PPP1CA
Gene expression profile of anticancer drug treated cell-lines (CCLE)
Heatmap showing the correlation between gene expression and drug response across all the cell-lines. We chose the top 20 among 138 drugs.We used Pearson's correlation coefficient.

Gene-centered drug-gene interaction network
Drug information targeting mutLBSgene (Approved drugs only)
Drug statusDrugBank IDNameTypeDrug structure
ExperimentalDB025062,6,8-Trimethyl-3-Amino-9-Benzyl-9-Methoxynonanoic AcidSmall molecule

Gene-centered ligand-gene interaction network

Ligands binding to mutated ligand binding site of PPP1CA go to BioLip
Ligand IDLigand short nameLigand long namePDB IDPDB namemutLBS
E7B(2Z)-2-[(1R)-3-{[(1R,2S,3R,6S,7S,10R)-10-{(2S,3S,6R,8S,9R)-3,9-DIMETHYL-8-[(3S)-3-METHYL-4-OXOPENTYL]-1,7-DIOXASPIRO[5.5]UNDEC-2-YL}-3,7-DIHYDROXY-2-METHOXY-6-METHYL-1-(1-METHYLETHYL)-5-OXOUNDECYL]OXY}-1-HYDROXY-3-OXOPROPYL]-3-METHYLBUT-2-ENEDIOIC ACID3e7bAC127 D220 Y272
E7B(2Z)-2-[(1R)-3-{[(1R,2S,3R,6S,7S,10R)-10-{(2S,3S,6R,8S,9R)-3,9-DIMETHYL-8-[(3S)-3-METHYL-4-OXOPENTYL]-1,7-DIOXASPIRO[5.5]UNDEC-2-YL}-3,7-DIHYDROXY-2-METHOXY-6-METHYL-1-(1-METHYLETHYL)-5-OXOUNDECYL]OXY}-1-HYDROXY-3-OXOPROPYL]-3-METHYLBUT-2-ENEDIOIC ACID3e7bBC127 D220 Y272
IIIPeptide ligand (ACB,ARG,1ZN,FGA,MDH)3e7aAD220 Y272
AZIAZIDE3e7bAE252
AZIAZIDE3e7bBE252
MNMANGANESE(2+)3eggAH125
MNMANGANESE(2+)3eggBH125
MNMANGANESE(2+)3eghAH125
MNMANGANESE(2+)3hvqAH125
MNMANGANESE(2+)3n5uAH125
MNMANGANESE(2+)3n5uBH125
MNMANGANESE(2+)3v4yAH125
MNMANGANESE(2+)3v4yCH125
MNMANGANESE(2+)3v4yEH125
MNMANGANESE(2+)4g9jAH125
MNMANGANESE(2+)4g9jBH125
MNMANGANESE(2+)4movAH125
MNMANGANESE(2+)4movBH125
MNMANGANESE(2+)4moyAH125
MNMANGANESE(2+)4xpnAH125
MNMANGANESE(2+)4xpnAH125
PO4PHOSPHATE ION4xpnAH125
MNMANGANESE(2+)4xpnCH125
MNMANGANESE(2+)3n5uAH125 Y272
PO4PHOSPHATE ION4xpnCH125 Y272
AZIAZIDE3e7bAR191
AZIAZIDE3e7bBR191
IIIPeptide ligand (GLU,THR,GLU,LEU,ASP,ASN,LEU,THR,GLU,PHE,ASN,THR,ALA,HIS,ASN,LYS,ARG,ILE,SER,THR,LEU,THR,ILE,GLU,GLU)3v4yAR191 D194
IIIPeptide ligand (ALA,MET,GLU,GLU,GLU,THR,GLU,LEU,ASP,ASN,LEU,THR,GLU,PHE,ASN,THR,ALA,HIS,ASN,LYS,ARG,ILE,SER)3v4yCR191 D194
IIIPeptide ligand (GLU,GLU,THR,GLU,LEU,ASP,ASN,LEU,THR,GLU,PHE,ASN,THR,ALA,HIS,ASN,LYS,ARG,ILE,SER,THR,LEU,THR,ILE)3v4yER191 D194
IIIPeptide ligand (ALA,MET,GLU,GLU,GLU,THR,GLU,LEU,ASP,ASN,LEU,THR,GLU,PHE,ASN,THR,ALA,HIS,ASN,LYS,ARG,ILE,SER,THR,LEU,THR,ILE,GLU)3v4yGR191 D194
IIIPeptide ligand (ACB,ARG,1ZN,FGA,MDH)3eghAY272
MNMANGANESE(2+)3n5uBY272


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Conservation information for LBS of PPP1CA
Multiple alignments for P62136 in multiple species
LBSAA sequence# speciesSpecies
A128GNHECASINRI10Homo sapiens, Arabidopsis thaliana, Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Ca
A57LLELEAPLKIC6Homo sapiens, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
A57LLELEAPIKIC3Arabidopsis thaliana, Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
A57LLELAAPVKIC1Arabidopsis thaliana
C127RGNHECASINR10Homo sapiens, Arabidopsis thaliana, Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Ca
C202DQGLLCDLLWS5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
C202DAGLLCDLLWS1Arabidopsis thaliana
C202DSGLLCDLLWS1Arabidopsis thaliana
C202DTGLLCDLLWS1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
C202DVGLLCDLLWS1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
C202DCGLLCDLLWS1Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
C273SAPNYCGEFDN10Homo sapiens, Arabidopsis thaliana, Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Ca
C291DETLMCSFQIL5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
C291DESLLCSFQIL3Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
C291DESLMCSFQIL2Arabidopsis thaliana, Arabidopsis thaliana
D154WKTFTDCFNCL8Homo sapiens, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Caenorhabditis elegans, Bos taurus, Rattus nor
D154WKVFTDTFNCL1Arabidopsis thaliana
D154WKVFTDSFNCL1Arabidopsis thaliana
D166IAAIVDEKIFC4Homo sapiens, Bos taurus, Rattus norvegicus, Mus musculus
D166IAAIIDEKIFT2Schizosaccharomyces pombe (strain 972 / ATCC 24843), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
D166VAAVIDEKILC1Arabidopsis thaliana
D166VAAVIDDKILC1Arabidopsis thaliana
D166IAAIIDEKIFC1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
D166VAAIIDEKIFC1Caenorhabditis elegans
D179GGLSPDLQSME5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
D179GGLSPDLNSME2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
D179GGLSPELINVE1Arabidopsis thaliana
D179GGLSPDLTNVE1Arabidopsis thaliana
D179GGLSPDLNSMD1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
D194IMRPTDVPDQG5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
D194IERPTDVPDAG1Arabidopsis thaliana
D194IKRPTDVPDSG1Arabidopsis thaliana
D194IMRPTDVPDTG1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
D194VMRPTDIPDVG1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
D194VMRPTDIPDCG1Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
D197PTDVPDQGLLC5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
D197PTDVPDAGLLC1Arabidopsis thaliana
D197PTDVPDSGLLC1Arabidopsis thaliana
D197PTDVPDTGLLC1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
D197PTDIPDVGLLC1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
D197PTDIPDCGLLC1Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
D220GWGENDRGVSF5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
D220GWGMNDRGVSY2Arabidopsis thaliana, Arabidopsis thaliana
D220GWSENDRGVSF2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
D220GWGDNDRGVSF1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
D242HKHDLDLICRA5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
D242IKNDMDLVCRA1Arabidopsis thaliana
D242IKNDMDLICRA1Arabidopsis thaliana
D242HKHDMDLVCRA1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
D242QKQDMELICRA1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
D242QKHDMDLICRA1Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
D277YCGEFDNAGAM8Homo sapiens, Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Bos taurus, Rattus norve
D277YCGEFDNAGAL1Arabidopsis thaliana
D277YCGEFDNAGSM1Caenorhabditis elegans
D64LKICGDIHGQY5Homo sapiens, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Bos taurus, Rattus norvegicus, Mus musculus
D64IKICGDIHGQY3Arabidopsis thaliana, Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
D64VKICGDIHGQY1Arabidopsis thaliana
D64LKICGDVHGQY1Caenorhabditis elegans
D71HGQYYDLLRLF8Homo sapiens, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Caenorhabditis elegans, Bos taurus, Rattus nor
D71HGQYSDLLRLF2Arabidopsis thaliana, Arabidopsis thaliana
D92YLFLGDYVDRG10Homo sapiens, Arabidopsis thaliana, Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Ca
E184DLQSMEQIRRI5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
E184DLNSMEQIRRV2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
E184ELINVEQIKNI1Arabidopsis thaliana
E184DLTNVEQIKNI1Arabidopsis thaliana
E184DLNSMDQIQRI1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
E230FTFGAEVVAKF4Homo sapiens, Bos taurus, Rattus norvegicus, Mus musculus
E230FTFGPDVVSRF2Schizosaccharomyces pombe (strain 972 / ATCC 24843), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
E230YTFGADKVAEF1Arabidopsis thaliana
E230YTFGPDKVAEF1Arabidopsis thaliana
E230FTFGPDVVNRF1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
E230FTFGPEVVAKF1Caenorhabditis elegans
E252AHQVVEDGYEF10Homo sapiens, Arabidopsis thaliana, Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Ca
E256VEDGYEFFAKR5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
E256VEDGYEFFSKR3Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
E256VEDGYEFFADR2Arabidopsis thaliana, Arabidopsis thaliana
E275PNYCGEFDNAG10Homo sapiens, Arabidopsis thaliana, Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Ca
E287MMSVDETLMCS4Homo sapiens, Bos taurus, Rattus norvegicus, Mus musculus
E287MMSVDESLLCS3Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
E287LMSVDESLMCS1Arabidopsis thaliana
E287MMSVDESLMCS1Arabidopsis thaliana
E287MMTVDETLMCS1Caenorhabditis elegans
F257EDGYEFFAKRQ5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
F257EDGYEFFSKRQ3Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
F257EDGYEFFADRQ2Arabidopsis thaliana, Arabidopsis thaliana
F258DGYEFFAKRQL5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
F258DGYEFFSKRQL3Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
F258DGYEFFADRQL2Arabidopsis thaliana, Arabidopsis thaliana
F276NYCGEFDNAGA9Homo sapiens, Arabidopsis thaliana, Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Bo
F276NYCGEFDNAGS1Caenorhabditis elegans
F293TLMCSFQILKP5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
F293SLLCSFQILKP3Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
F293SLMCSFQILKP2Arabidopsis thaliana, Arabidopsis thaliana
G199DVPDQGLLCDL5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
G199DVPDAGLLCDL1Arabidopsis thaliana
G199DVPDSGLLCDL1Arabidopsis thaliana
G199DVPDTGLLCDL1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
G199DIPDVGLLCDL1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
G199DIPDCGLLCDL1Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
G215DKDVQGWGEND4Homo sapiens, Bos taurus, Rattus norvegicus, Mus musculus
G215SKDVKGWGMND2Arabidopsis thaliana, Arabidopsis thaliana
G215DKDLTGWGDND1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
G215DKDIVGWSEND1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
G215DKDITGWSEND1Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
G215DKDVTGWGEND1Caenorhabditis elegans
G222GENDRGVSFTF5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
G222GMNDRGVSYTF2Arabidopsis thaliana, Arabidopsis thaliana
G222SENDRGVSFTF2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
G222GDNDRGVSFTF1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
G274APNYCGEFDNA10Homo sapiens, Arabidopsis thaliana, Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Ca
G97DYVDRGKQSLE10Homo sapiens, Arabidopsis thaliana, Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Ca
H125LLRGNHECASI7Homo sapiens, Arabidopsis thaliana, Arabidopsis thaliana, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
H125ILRGNHECASI3Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
H173KIFCCHGGLSP5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
H173KILCMHGGLSP2Arabidopsis thaliana, Arabidopsis thaliana
H173KIFTMHGGLSP2Schizosaccharomyces pombe (strain 972 / ATCC 24843), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
H173KIFCMHGGLSP1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
H248LICRAHQVVED8Homo sapiens, Arabidopsis thaliana, Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
H248LVCRAHQVVED2Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843)
H66ICGDIHGQYYD7Homo sapiens, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Bos taurus, Rattus norvegicus, Mus musculus
H66ICGDIHGQYSD2Arabidopsis thaliana, Arabidopsis thaliana
H66ICGDVHGQYYD1Caenorhabditis elegans
I130HECASINRIYG10Homo sapiens, Arabidopsis thaliana, Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Ca
I133ASINRIYGFYD10Homo sapiens, Arabidopsis thaliana, Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Ca
I169IVDEKIFCCHG4Homo sapiens, Bos taurus, Rattus norvegicus, Mus musculus
I169IIDEKIFTMHG2Schizosaccharomyces pombe (strain 972 / ATCC 24843), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
I169VIDEKILCMHG1Arabidopsis thaliana
I169VIDDKILCMHG1Arabidopsis thaliana
I169IIDEKIFCMHG1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
I169IIDEKIFCCHG1Caenorhabditis elegans
I189EQIRRIMRPTD5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
I189EQIRRVMRPTD2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
I189EQIKNIERPTD1Arabidopsis thaliana
I189EQIKNIKRPTD1Arabidopsis thaliana
I189DQIQRIMRPTD1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
I295MCSFQILKPAD6Homo sapiens, Arabidopsis thaliana, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
I295LCSFQILKPAE2Schizosaccharomyces pombe (strain 972 / ATCC 24843), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
I295MCSFQILKPVD1Arabidopsis thaliana
I295LCSFQILKPAQ1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
K150NIKLWKTFTDC8Homo sapiens, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Caenorhabditis elegans, Bos taurus, Rattus nor
K150NVKLWKVFTDT1Arabidopsis thaliana
K150SVRLWKVFTDS1Arabidopsis thaliana
K168AIVDEKIFCCH4Homo sapiens, Bos taurus, Rattus norvegicus, Mus musculus
K168AIIDEKIFTMH2Schizosaccharomyces pombe (strain 972 / ATCC 24843), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
K168AVIDEKILCMH1Arabidopsis thaliana
K168AVIDDKILCMH1Arabidopsis thaliana
K168AIIDEKIFCMH1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
K168AIIDEKIFCCH1Caenorhabditis elegans
K260YEFFAKRQLVT5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
K260YEFFSKRQLVT3Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
K260YEFFADRQLVT2Arabidopsis thaliana, Arabidopsis thaliana
K297SFQILKPADKN4Homo sapiens, Bos taurus, Rattus norvegicus, Mus musculus
K297SFQILKPAEK-2Schizosaccharomyces pombe (strain 972 / ATCC 24843), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
K297SFQILKPVDR-1Arabidopsis thaliana
K297SFQILKPADR-1Arabidopsis thaliana
K297SFQILKPAQKS1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
K297SFQILKPADKK1Caenorhabditis elegans
K6MSDSEKLNLDS4Homo sapiens, Bos taurus, Rattus norvegicus, Mus musculus
K6QGSMDPAVLDD1Arabidopsis thaliana
K6QGSMDPAALDD1Arabidopsis thaliana
K6MSNPD-VDLDS1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
K6-MDSQPVDVDN1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
K6MADHTEVDLDS1Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
K6-MDVEKLNLDN1Caenorhabditis elegans
L200VPDQGLLCDLL5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
L200VPDAGLLCDLL1Arabidopsis thaliana
L200VPDSGLLCDLL1Arabidopsis thaliana
L200VPDTGLLCDLL1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
L200IPDVGLLCDLL1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
L200IPDCGLLCDLL1Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
L201PDQGLLCDLLW5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
L201PDAGLLCDLLW1Arabidopsis thaliana
L201PDSGLLCDLLW1Arabidopsis thaliana
L201PDTGLLCDLLW1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
L201PDVGLLCDLLW1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
L201PDCGLLCDLLW1Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
L243KHDLDLICRAH5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
L243KNDMDLVCRAH1Arabidopsis thaliana
L243KNDMDLICRAH1Arabidopsis thaliana
L243KHDMDLVCRAH1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
L243KQDMELICRAH1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
L243KHDMDLICRAH1Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
L289SVDETLMCSFQ4Homo sapiens, Bos taurus, Rattus norvegicus, Mus musculus
L289SVDESLLCSFQ3Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
L289SVDESLMCSFQ2Arabidopsis thaliana, Arabidopsis thaliana
L289TVDETLMCSFQ1Caenorhabditis elegans
L296CSFQILKPADK5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
L296CSFQILKPAEK2Schizosaccharomyces pombe (strain 972 / ATCC 24843), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
L296CSFQILKPVDR1Arabidopsis thaliana
L296CSFQILKPADR1Arabidopsis thaliana
L296CSFQILKPAQK1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
L40IRGLCLKSREI4Homo sapiens, Bos taurus, Rattus norvegicus, Mus musculus
L40IRQLCFVSREI1Arabidopsis thaliana
L40IRQLCIVSREI1Arabidopsis thaliana
L40IRFLCNKAREI1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
L40IRYLCSKARSI1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
L40IRYLCTKAREI1Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
L40IKGLCQKSREI1Caenorhabditis elegans
L47SREIFLSQPIL5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
L47AREIFISQPIL2Schizosaccharomyces pombe (strain 972 / ATCC 24843), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
L47SREIFLQQPCL1Arabidopsis thaliana
L47SREIFLQQPNL1Arabidopsis thaliana
L47ARSIFIKQPIL1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
L75YDLLRLFEYGG8Homo sapiens, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Caenorhabditis elegans, Bos taurus, Rattus nor
L75SDLLRLFEYGG2Arabidopsis thaliana, Arabidopsis thaliana
M190QIRRIMRPTDV5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
M190QIRRVMRPTDI2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
M190QIKNIERPTDV1Arabidopsis thaliana
M190QIKNIKRPTDV1Arabidopsis thaliana
M190QIQRIMRPTDV1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
M282DNAGAMMSVDE8Homo sapiens, Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Bos taurus, Rattus norve
M282DNAGALMSVDE1Arabidopsis thaliana
M282DNAGSMMTVDE1Caenorhabditis elegans
M290VDETLMCSFQI5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
M290VDESLLCSFQI3Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
M290VDESLMCSFQI2Arabidopsis thaliana, Arabidopsis thaliana
N124FLLRGNHECAS7Homo sapiens, Arabidopsis thaliana, Arabidopsis thaliana, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
N124FILRGNHECAS3Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
N157FTDCFNCLPIA7Homo sapiens, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Bos taurus, Rattus norvegicus, Mus musculus
N157FTDTFNCLPVA1Arabidopsis thaliana
N157FTDSFNCLPVA1Arabidopsis thaliana
N157FTDCFNCLPVA1Caenorhabditis elegans
N271LFSAPNYCGEF8Homo sapiens, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Caenorhabditis elegans, Bos taurus, Rattus nor
N271MFSAPNYCGEF1Arabidopsis thaliana
N271IFSAPNYCGEF1Arabidopsis thaliana
N278CGEFDNAGAMM8Homo sapiens, Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Bos taurus, Rattus norve
N278CGEFDNAGALM1Arabidopsis thaliana
N278CGEFDNAGSMM1Caenorhabditis elegans
P192RRIMRPTDVPD5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
P192RRVMRPTDIPD2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
P192KNIERPTDVPD1Arabidopsis thaliana
P192KNIKRPTDVPD1Arabidopsis thaliana
P192QRIMRPTDVPD1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P196RPTDVPDQGLL5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
P196RPTDVPDAGLL1Arabidopsis thaliana
P196RPTDVPDSGLL1Arabidopsis thaliana
P196RPTDVPDTGLL1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P196RPTDIPDVGLL1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P196RPTDIPDCGLL1Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
P24VQGSRPG-KNV4Homo sapiens, Bos taurus, Rattus norvegicus, Mus musculus
P24YRNPKAGTKQA1Arabidopsis thaliana
P24YRNPKPGTKQA1Arabidopsis thaliana
P24VRGSRPG-RQV1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
P24VRGSKPG-QQV1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
P24VRGSRPG-KQV1Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
P24VRGSKPG-KNV1Caenorhabditis elegans
P270TLFSAPNYCGE8Homo sapiens, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Caenorhabditis elegans, Bos taurus, Rattus nor
P270TMFSAPNYCGE1Arabidopsis thaliana
P270TIFSAPNYCGE1Arabidopsis thaliana
Q181LSPDLQSMEQI5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
Q181LSPDLNSMEQI2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Q181LSPELINVEQI1Arabidopsis thaliana
Q181LSPDLTNVEQI1Arabidopsis thaliana
Q181LSPDLNSMDQI1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q185LQSMEQIRRIM5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
Q185LNSMEQIRRVM2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Q185LINVEQIKNIE1Arabidopsis thaliana
Q185LTNVEQIKNIK1Arabidopsis thaliana
Q185LNSMDQIQRIM1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q198TDVPDQGLLCD5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
Q198TDVPDAGLLCD1Arabidopsis thaliana
Q198TDVPDSGLLCD1Arabidopsis thaliana
Q198TDVPDTGLLCD1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q198TDIPDVGLLCD1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Q198TDIPDCGLLCD1Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Q249ICRAHQVVEDG8Homo sapiens, Arabidopsis thaliana, Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
Q249VCRAHQVVEDG2Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Q294LMCSFQILKPA6Homo sapiens, Arabidopsis thaliana, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
Q294LLCSFQILKPA3Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Q294LMCSFQILKPV1Arabidopsis thaliana
Q68GDIHGQYYDLL7Homo sapiens, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Bos taurus, Rattus norvegicus, Mus musculus
Q68GDIHGQYSDLL2Arabidopsis thaliana, Arabidopsis thaliana
Q68GDVHGQYYDLL1Caenorhabditis elegans
R132CASINRIYGFY10Homo sapiens, Arabidopsis thaliana, Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Ca
R188MEQIRRIMRPT5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
R188MEQIRRVMRPT2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
R188VEQIKNIERPT1Arabidopsis thaliana
R188VEQIKNIKRPT1Arabidopsis thaliana
R188MDQIQRIMRPT1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
R191IRRIMRPTDVP5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
R191IRRVMRPTDIP2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
R191IKNIERPTDVP1Arabidopsis thaliana
R191IKNIKRPTDVP1Arabidopsis thaliana
R191IQRIMRPTDVP1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
R221WGENDRGVSFT5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
R221WGMNDRGVSYT2Arabidopsis thaliana, Arabidopsis thaliana
R221WSENDRGVSFT2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
R221WGDNDRGVSFT1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
R261EFFAKRQLVTL5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
R261EFFSKRQLVTL3Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
R261EFFADRQLVTM1Arabidopsis thaliana
R261EFFADRQLVTI1Arabidopsis thaliana
R43LCLKSREIFLS4Homo sapiens, Bos taurus, Rattus norvegicus, Mus musculus
R43LCFVSREIFLQ1Arabidopsis thaliana
R43LCIVSREIFLQ1Arabidopsis thaliana
R43LCNKAREIFIS1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
R43LCSKARSIFIK1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
R43LCTKAREIFIS1Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
R43LCQKSREIFLS1Caenorhabditis elegans
R74YYDLLRLFEYG8Homo sapiens, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Caenorhabditis elegans, Bos taurus, Rattus nor
R74YSDLLRLFEYG2Arabidopsis thaliana, Arabidopsis thaliana
R96GDYVDRGKQSL10Homo sapiens, Arabidopsis thaliana, Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Ca
S129NHECASINRIY10Homo sapiens, Arabidopsis thaliana, Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Ca
S182SPDLQSMEQIR5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
S182SPDLNSMEQIR2Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
S182SPELINVEQIK1Arabidopsis thaliana
S182SPDLTNVEQIK1Arabidopsis thaliana
S182SPDLNSMDQIQ1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
S292ETLMCSFQILK5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
S292ESLLCSFQILK3Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
S292ESLMCSFQILK2Arabidopsis thaliana, Arabidopsis thaliana
T193RIMRPTDVPDQ5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
T193NIERPTDVPDA1Arabidopsis thaliana
T193NIKRPTDVPDS1Arabidopsis thaliana
T193RIMRPTDVPDT1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
T193RVMRPTDIPDV1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
T193RVMRPTDIPDC1Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
T288MSVDETLMCSF4Homo sapiens, Bos taurus, Rattus norvegicus, Mus musculus
T288MSVDESLLCSF3Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
T288MSVDESLMCSF2Arabidopsis thaliana, Arabidopsis thaliana
T288MTVDETLMCSF1Caenorhabditis elegans
V195MRPTDVPDQGL5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
V195ERPTDVPDAGL1Arabidopsis thaliana
V195KRPTDVPDSGL1Arabidopsis thaliana
V195MRPTDVPDTGL1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
V195MRPTDIPDVGL1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
V195MRPTDIPDCGL1Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
V223ENDRGVSFTFG7Homo sapiens, Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
V223MNDRGVSYTFG2Arabidopsis thaliana, Arabidopsis thaliana
V223DNDRGVSFTFG1Schizosaccharomyces pombe (strain 972 / ATCC 24843)
V231TFGAEVVAKFL4Homo sapiens, Bos taurus, Rattus norvegicus, Mus musculus
V231TFGPDVVSRFL2Schizosaccharomyces pombe (strain 972 / ATCC 24843), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
V231TFGADKVAEFL1Arabidopsis thaliana
V231TFGPDKVAEFL1Arabidopsis thaliana
V231TFGPDVVNRFL1Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
V231TFGPEVVAKFL1Caenorhabditis elegans
V250CRAHQVVEDGY10Homo sapiens, Arabidopsis thaliana, Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Ca
W206LCDLLWSDPDK8Homo sapiens, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Caenorhabditis elegans, Bos taurus, Rattus nor
W206LCDLLWSDPSK2Arabidopsis thaliana, Arabidopsis thaliana
Y134SINRIYGFYDE10Homo sapiens, Arabidopsis thaliana, Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Ca
Y255VVEDGYEFFAK5Homo sapiens, Caenorhabditis elegans, Bos taurus, Rattus norvegicus, Mus musculus
Y255VVEDGYEFFSK3Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Y255VVEDGYEFFAD2Arabidopsis thaliana, Arabidopsis thaliana
Y272FSAPNYCGEFD10Homo sapiens, Arabidopsis thaliana, Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Ca
Y70IHGQYYDLLRL7Homo sapiens, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Bos taurus, Rattus norvegicus, Mus musculus
Y70IHGQYSDLLRL2Arabidopsis thaliana, Arabidopsis thaliana
Y70VHGQYYDLLRL1Caenorhabditis elegans
Y78LRLFEYGGFPP10Homo sapiens, Arabidopsis thaliana, Arabidopsis thaliana, Schizosaccharomyces pombe (strain 972 / ATCC 24843), Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), Ca


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