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  glioblastoma [Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Cla]

Displaying 21-30 of 45 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395816Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_C10glioblastoma [Cla]
GSE57872GSM1395818Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_C12glioblastoma [Cla]
GSE57872GSM1395821Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D03glioblastoma [Cla]
GSE57872GSM1395822Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D04glioblastoma [Cla]
GSE57872GSM1395824Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D06glioblastoma [Cla]
GSE57872GSM1395828Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D10glioblastoma [Cla]
GSE57872GSM1395830Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D12glioblastoma [Cla]
GSE57872GSM1395831Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_E01glioblastoma [Cla]
GSE57872GSM1395838Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_E08glioblastoma [Cla]
GSE57872GSM1395842Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_E12glioblastoma [Cla]

Gene rank in glioblastoma [Cla]

Displaying 21-30 of 5942 results.
Rank orderGene SymbolEnsembl ID
21TMEM45AENSG00000181458
22C6orf62ENSG00000112308
23HSPA5ENSG00000044574
24HNRNPA2B1ENSG00000122566
25PSAPENSG00000197746
26B2MENSG00000166710
27FTLENSG00000087086
28UBBENSG00000170315
29SKP1ENSG00000113558
30GPM6BENSG00000046653