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  glioblastoma [Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Cla]

Displaying 1-10 of 45 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395441Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_D07glioblastoma [Cla]
GSE57872GSM1395458Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_E12glioblastoma [Cla]
GSE57872GSM1395476Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_G06glioblastoma [Cla]
GSE57872GSM1395479Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_G09glioblastoma [Cla]
GSE57872GSM1395482Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_G12glioblastoma [Cla]
GSE57872GSM1395496Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_A02glioblastoma [Cla]
GSE57872GSM1395526Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_C08glioblastoma [Cla]
GSE57872GSM1395558Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_F04glioblastoma [Cla]
GSE57872GSM1395567Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_G01glioblastoma [Cla]
GSE57872GSM1395578Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_G12glioblastoma [Cla]

Gene rank in glioblastoma [Cla]

Displaying 61-70 of 5942 results.
Rank orderGene SymbolEnsembl ID
61SPARCL1ENSG00000152583
62ATP5A1ENSG00000152234
63SRSF6ENSG00000124193
64TMED10ENSG00000170348
65CALUENSG00000128595
66HSP90AA1ENSG00000080824
67ATP9BENSG00000166377
68EEF1GENSG00000254772
69GPIENSG00000105220
70PCSK5ENSG00000099139