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  glioblastoma [Mes]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Mes]

Displaying 71-80 of 101 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395749Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_F03glioblastoma [Mes]
GSE57872GSM1395750Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_F04glioblastoma [Mes]
GSE57872GSM1395756Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_F10glioblastoma [Mes]
GSE57872GSM1395758Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_F12glioblastoma [Mes]
GSE57872GSM1395762Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G04glioblastoma [Mes]
GSE57872GSM1395765Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G07glioblastoma [Mes]
GSE57872GSM1395766Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G08glioblastoma [Mes]
GSE57872GSM1395767Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G09glioblastoma [Mes]
GSE57872GSM1395769Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G11glioblastoma [Mes]
GSE57872GSM1395775Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H05glioblastoma [Mes]

Gene rank in glioblastoma [Mes]

Displaying 71-80 of 5942 results.
Rank orderGene SymbolEnsembl ID
71HEPN1ENSG00000221932
72UBBENSG00000170315
73EIF1ENSG00000173812
74CLIC4ENSG00000169504
75SEPT7ENSG00000122545
76TIMP1ENSG00000102265
77DDOSTENSG00000244038
78SRIENSG00000075142
79LAMP2ENSG00000005893
80LDHBENSG00000111716