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  glioblastoma [Mes]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Mes]

Displaying 11-20 of 101 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395880Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_A02glioblastoma [Mes]
GSE57872GSM1395873Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H07glioblastoma [Mes]
GSE57872GSM1395868Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H02glioblastoma [Mes]
GSE57872GSM1395860Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G06glioblastoma [Mes]
GSE57872GSM1395858Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_G04glioblastoma [Mes]
GSE57872GSM1395852Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F10glioblastoma [Mes]
GSE57872GSM1395829Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D11glioblastoma [Mes]
GSE57872GSM1395826Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D08glioblastoma [Mes]
GSE57872GSM1395814Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_C08glioblastoma [Mes]
GSE57872GSM1395782Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H12glioblastoma [Mes]

Gene rank in glioblastoma [Mes]

Displaying 11-20 of 5942 results.
Rank orderGene SymbolEnsembl ID
11DDX5ENSG00000108654
12MAP1BENSG00000131711
13B2MENSG00000166710
14HSPA8ENSG00000109971
15ALDOAENSG00000149925
16FTLENSG00000087086
17UBCENSG00000150991
18PSAPENSG00000197746
19HSPA5ENSG00000044574
20ENO1ENSG00000074800