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  glioblastoma [Mes]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Mes]

Displaying 11-20 of 101 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395607Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_B05glioblastoma [Mes]
GSE57872GSM1395609Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_B07glioblastoma [Mes]
GSE57872GSM1395610Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_B08glioblastoma [Mes]
GSE57872GSM1395612Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_B10glioblastoma [Mes]
GSE57872GSM1395613Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_B11glioblastoma [Mes]
GSE57872GSM1395617Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C03glioblastoma [Mes]
GSE57872GSM1395619Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C05glioblastoma [Mes]
GSE57872GSM1395620Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C06glioblastoma [Mes]
GSE57872GSM1395621Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C07glioblastoma [Mes]
GSE57872GSM1395622Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C08glioblastoma [Mes]

Gene rank in glioblastoma [Mes]

Displaying 5821-5830 of 5942 results.
Rank orderGene SymbolEnsembl ID
5821TNFRSF11BENSG00000164761
5822ISG15ENSG00000187608
5823HSPBAP1ENSG00000169087
5824MECOMENSG00000085276
5825PTPRDENSG00000153707
5826PELI2ENSG00000139946
5827SLAIN1ENSG00000139737
5828TNFRSF21ENSG00000146072
5829LAMA1ENSG00000101680
5830GABRB1ENSG00000163288