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  glioblastoma [Neu+Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Neu+Cla]

Displaying 1-2 of 2 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395423Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_C01glioblastoma [Neu+Cla]
GSE57872GSM1395797Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_B03glioblastoma [Neu+Cla]

Gene rank in glioblastoma [Neu+Cla]

Displaying 21-30 of 5942 results.
Rank orderGene SymbolEnsembl ID
21LDHAENSG00000134333
22MT2AENSG00000125148
23CLUENSG00000120885
24PPIAENSG00000196262
25HNRNPA2B1ENSG00000122566
26HSPA8ENSG00000109971
27ATP5A1ENSG00000152234
28PSAPENSG00000197746
29CALM1ENSG00000198668
30RPL3ENSG00000100316