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  glioblastoma [Neu+Mes]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Neu+Mes]

Displaying 1-10 of 19 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395616Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C02glioblastoma [Neu+Mes]
GSE57872GSM1395638Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_D12glioblastoma [Neu+Mes]
GSE57872GSM1395642Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_E04glioblastoma [Neu+Mes]
GSE57872GSM1395651Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_F01glioblastoma [Neu+Mes]
GSE57872GSM1395662Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_F12glioblastoma [Neu+Mes]
GSE57872GSM1395672Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_G10glioblastoma [Neu+Mes]
GSE57872GSM1395686Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_H12glioblastoma [Neu+Mes]
GSE57872GSM1395687Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_A01glioblastoma [Neu+Mes]
GSE57872GSM1395693Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_A07glioblastoma [Neu+Mes]
GSE57872GSM1395694Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_A08glioblastoma [Neu+Mes]

Gene rank in glioblastoma [Neu+Mes]

Displaying 41-50 of 5942 results.
Rank orderGene SymbolEnsembl ID
41GAP43ENSG00000172020
42TMSB4XENSG00000205542
43GPM6AENSG00000150625
44ITGB8ENSG00000105855
45SEPT2ENSG00000168385
46AQP4ENSG00000171885
47HNRNPA2B1ENSG00000122566
48AGTENSG00000135744
49SLC1A3ENSG00000079215
50TMED10ENSG00000170348