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  glioblastoma [Neu]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Neu]

Displaying 1-10 of 24 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395440Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_D06glioblastoma [Neu]
GSE57872GSM1395689Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_A03glioblastoma [Neu]
GSE57872GSM1395704Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_B06glioblastoma [Neu]
GSE57872GSM1395713Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_C03glioblastoma [Neu]
GSE57872GSM1395718Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_C08glioblastoma [Neu]
GSE57872GSM1395725Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_D03glioblastoma [Neu]
GSE57872GSM1395764Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G06glioblastoma [Neu]
GSE57872GSM1395771Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H01glioblastoma [Neu]
GSE57872GSM1395772Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H02glioblastoma [Neu]
GSE57872GSM1395774Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H04glioblastoma [Neu]

Gene rank in glioblastoma [Neu]

Displaying 31-40 of 5942 results.
Rank orderGene SymbolEnsembl ID
31GFAPENSG00000131095
32NAMPTENSG00000105835
33ATP9BENSG00000166377
34HNRNPA2B1ENSG00000122566
35MT-CYBENSG00000198727
36PTPRZ1ENSG00000106278
37SKP1ENSG00000113558
38SLC1A3ENSG00000079215
39SEPT2ENSG00000168385
40HEPN1ENSG00000221932