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  glioblastoma [Neu]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Neu]

Displaying 1-10 of 24 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395440Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_D06glioblastoma [Neu]
GSE57872GSM1395689Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_A03glioblastoma [Neu]
GSE57872GSM1395704Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_B06glioblastoma [Neu]
GSE57872GSM1395713Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_C03glioblastoma [Neu]
GSE57872GSM1395718Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_C08glioblastoma [Neu]
GSE57872GSM1395725Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_D03glioblastoma [Neu]
GSE57872GSM1395764Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G06glioblastoma [Neu]
GSE57872GSM1395771Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H01glioblastoma [Neu]
GSE57872GSM1395772Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H02glioblastoma [Neu]
GSE57872GSM1395774Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H04glioblastoma [Neu]

Gene rank in glioblastoma [Neu]

Displaying 41-50 of 5942 results.
Rank orderGene SymbolEnsembl ID
41PGK1ENSG00000102144
42HSP90AA1ENSG00000080824
43EIF1ENSG00000173812
44TUBA1BENSG00000123416
45AQP4ENSG00000171885
46RPL15ENSG00000174748
47CANXENSG00000127022
48ANXA5ENSG00000164111
49CALM2ENSG00000143933
50SPARCL1ENSG00000152583