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  glioblastoma [Pro+Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Pro+Cla]

Displaying 1-10 of 20 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395401Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_A03glioblastoma [Pro+Cla]
GSE57872GSM1395403Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_A05glioblastoma [Pro+Cla]
GSE57872GSM1395411Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_B01glioblastoma [Pro+Cla]
GSE57872GSM1395425Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_C03glioblastoma [Pro+Cla]
GSE57872GSM1395434Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_C12glioblastoma [Pro+Cla]
GSE57872GSM1395435Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_D01glioblastoma [Pro+Cla]
GSE57872GSM1395450Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_E04glioblastoma [Pro+Cla]
GSE57872GSM1395468Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_F10glioblastoma [Pro+Cla]
GSE57872GSM1395508Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B02glioblastoma [Pro+Cla]
GSE57872GSM1395511Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B05glioblastoma [Pro+Cla]

Gene rank in glioblastoma [Pro+Cla]

Displaying 31-40 of 5942 results.
Rank orderGene SymbolEnsembl ID
31HNRNPA1ENSG00000135486
32GLULENSG00000135821
33DBIENSG00000155368
34PSAPENSG00000197746
35LDHBENSG00000111716
36LDHAENSG00000134333
37GNB2L1
38UBBENSG00000170315
39MT-CYBENSG00000198727
40PTNENSG00000105894