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  glioblastoma [Pro+Neu]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Pro+Neu]

Displaying 1-5 of 5 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395801Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_B07glioblastoma [Pro+Neu]
GSE57872GSM1395815Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_C09glioblastoma [Pro+Neu]
GSE57872GSM1395427Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_C05glioblastoma [Pro+Neu]
GSE57872GSM1395703Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_B05glioblastoma [Pro+Neu]
GSE57872GSM1395480Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_G10glioblastoma [Pro+Neu]

Gene rank in glioblastoma [Pro+Neu]

Displaying 71-80 of 5942 results.
Rank orderGene SymbolEnsembl ID
71RPN1ENSG00000163902
72MAP1BENSG00000131711
73NRCAMENSG00000091129
74IDH1ENSG00000138413
75SRP9ENSG00000143742
76ATP9BENSG00000166377
77MYL6ENSG00000092841
78RPLP0ENSG00000089157
79VCANENSG00000038427
80HEPN1ENSG00000221932