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  zygote (2PN)-bad

Overall DesignWe sequenced the transcriptomes of 22 human zygotes (2PN stage) embryos, of which 11 were predicted nonviable and 11 were predicted viable. We excluded 5 which had no siblings in this data set. From the remaining 17 embryos, we analyzed the set of genes that was differentially expressed between those predicted viable and those predicted nonviable.
SummaryWe sorted 2PN stage human embryos by predicted viability using a noninvasive measurement we previously developed. We then performed RNA-seq on each embryo (which was a single cell) and looked for differences in expression between viable and nonviable embryos.
Dataset viewGSE65481
PMID26904963

Samples in zygote (2PN)-bad

Displaying 11-11 of 11 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE65481GSM1598286Illumina HiSeq 2000Homo sapiensS5zygote (2PN)-bad

Gene rank in zygote (2PN)-bad

Displaying 71-80 of 19195 results.
Rank orderGene SymbolEnsembl ID
71PSMA2ENSG00000106588
72CENPEENSG00000138778
73RNF34ENSG00000170633
74SH2D4AENSG00000104611
75RPS19ENSG00000105372
76DCDC2ENSG00000146038
77NOC3LENSG00000173145
78COPS8ENSG00000198612
79CSDE1ENSG00000009307
80MORF4L1ENSG00000185787