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  zygote (2PN)-bad

Overall DesignWe sequenced the transcriptomes of 22 human zygotes (2PN stage) embryos, of which 11 were predicted nonviable and 11 were predicted viable. We excluded 5 which had no siblings in this data set. From the remaining 17 embryos, we analyzed the set of genes that was differentially expressed between those predicted viable and those predicted nonviable.
SummaryWe sorted 2PN stage human embryos by predicted viability using a noninvasive measurement we previously developed. We then performed RNA-seq on each embryo (which was a single cell) and looked for differences in expression between viable and nonviable embryos.
Dataset viewGSE65481
PMID26904963

Samples in zygote (2PN)-bad

Displaying 11-11 of 11 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE65481GSM1598303Illumina HiSeq 2000Homo sapiensS22zygote (2PN)-bad

Gene rank in zygote (2PN)-bad

Displaying 81-90 of 19195 results.
Rank orderGene SymbolEnsembl ID
81CCDC25ENSG00000147419
82ARMC2ENSG00000118690
83IPO8ENSG00000133704
84MLL3
85PTGES3ENSG00000110958
86RPS13ENSG00000110700
87SIN3AENSG00000169375
88RPL30ENSG00000156482
89PRPF40AENSG00000196504
90CCNIENSG00000118816