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  zygote (2PN)-bad

Overall DesignWe sequenced the transcriptomes of 22 human zygotes (2PN stage) embryos, of which 11 were predicted nonviable and 11 were predicted viable. We excluded 5 which had no siblings in this data set. From the remaining 17 embryos, we analyzed the set of genes that was differentially expressed between those predicted viable and those predicted nonviable.
SummaryWe sorted 2PN stage human embryos by predicted viability using a noninvasive measurement we previously developed. We then performed RNA-seq on each embryo (which was a single cell) and looked for differences in expression between viable and nonviable embryos.
Dataset viewGSE65481
PMID26904963

Samples in zygote (2PN)-bad

Displaying 11-11 of 11 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE65481GSM1598303Illumina HiSeq 2000Homo sapiensS22zygote (2PN)-bad

Gene rank in zygote (2PN)-bad

Displaying 51-60 of 19195 results.
Rank orderGene SymbolEnsembl ID
51SKP1ENSG00000113558
52AMD1ENSG00000123505
53DAAM1ENSG00000100592
54DCP2ENSG00000172795
55CALM1ENSG00000198668
56SPDL1ENSG00000040275
57GEMIN5ENSG00000082516
58LARP7ENSG00000174720
59CCNB1ENSG00000134057
60SMC3ENSG00000108055