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  zygote (2PN)-good

Overall DesignWe sequenced the transcriptomes of 22 human zygotes (2PN stage) embryos, of which 11 were predicted nonviable and 11 were predicted viable. We excluded 5 which had no siblings in this data set. From the remaining 17 embryos, we analyzed the set of genes that was differentially expressed between those predicted viable and those predicted nonviable.
SummaryWe sorted 2PN stage human embryos by predicted viability using a noninvasive measurement we previously developed. We then performed RNA-seq on each embryo (which was a single cell) and looked for differences in expression between viable and nonviable embryos.
Dataset viewGSE65481
PMID26904963

Samples in zygote (2PN)-good

Displaying 11-11 of 11 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE65481GSM1598302Illumina HiSeq 2000Homo sapiensS21zygote (2PN)-good

Gene rank in zygote (2PN)-good

Displaying 11-20 of 19195 results.
Rank orderGene SymbolEnsembl ID
11TUBB8ENSG00000261456
12UHRF1ENSG00000276043
13OTX2ENSG00000165588
14PCNAENSG00000132646
15TAX1BP1ENSG00000106052
16TUBA1CENSG00000167553
17UBE2Q2ENSG00000140367
18NLRP4ENSG00000160505
19HSPA8ENSG00000109971
20UBBENSG00000170315