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  zygote (2PN)-good

Overall DesignWe sequenced the transcriptomes of 22 human zygotes (2PN stage) embryos, of which 11 were predicted nonviable and 11 were predicted viable. We excluded 5 which had no siblings in this data set. From the remaining 17 embryos, we analyzed the set of genes that was differentially expressed between those predicted viable and those predicted nonviable.
SummaryWe sorted 2PN stage human embryos by predicted viability using a noninvasive measurement we previously developed. We then performed RNA-seq on each embryo (which was a single cell) and looked for differences in expression between viable and nonviable embryos.
Dataset viewGSE65481
PMID26904963

Samples in zygote (2PN)-good

Displaying 11-11 of 11 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE65481GSM1598290Illumina HiSeq 2000Homo sapiensS9zygote (2PN)-good

Gene rank in zygote (2PN)-good

Displaying 51-60 of 19195 results.
Rank orderGene SymbolEnsembl ID
51DCP2ENSG00000172795
52EIF4A2ENSG00000156976
53OOEPENSG00000203907
54CALM1ENSG00000198668
55NPM1ENSG00000181163
56CENPEENSG00000138778
57FAM13AENSG00000138640
58GEMIN5ENSG00000082516
59CSDE1ENSG00000009307
60CCNB1ENSG00000134057