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  zygote (2PN)-good

Overall DesignWe sequenced the transcriptomes of 22 human zygotes (2PN stage) embryos, of which 11 were predicted nonviable and 11 were predicted viable. We excluded 5 which had no siblings in this data set. From the remaining 17 embryos, we analyzed the set of genes that was differentially expressed between those predicted viable and those predicted nonviable.
SummaryWe sorted 2PN stage human embryos by predicted viability using a noninvasive measurement we previously developed. We then performed RNA-seq on each embryo (which was a single cell) and looked for differences in expression between viable and nonviable embryos.
Dataset viewGSE65481
PMID26904963

Samples in zygote (2PN)-good

Displaying 11-11 of 11 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE65481GSM1598302Illumina HiSeq 2000Homo sapiensS21zygote (2PN)-good

Gene rank in zygote (2PN)-good

Displaying 81-90 of 19195 results.
Rank orderGene SymbolEnsembl ID
81PPP1CBENSG00000213639
82HINT1ENSG00000169567
83PSMA2ENSG00000106588
84NAP1L1ENSG00000187109
85MORF4L1ENSG00000185787
86WDFY1ENSG00000085449
87ARMC2ENSG00000118690
88USP34ENSG00000115464
89NOC3LENSG00000173145
90PRPF40AENSG00000196504