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Gene View

General Information

APP[ENSG00000142192]

SynonymsAAA;ABETA;ABPP;AD1;APPI;CTFgamma;CVAP;PN-II;PN2
Descriptionamyloid beta precursor protein
Chromosome21q21.3
Database ReferenceMIM:104760 HGNC:620 HPRD:00100 Vega:OTTHUMG00000078438 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE72056

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
APP expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
B-cell00787.161
CAF0219.64890.279
Endothelial cell0985.6082,785.573
Macrophage00550.989
melanoma001,464.314
melanoma tumor001,787.067
T-cell001,269.202
unresolved002,132.869
Displaying 1-20 of 28 results.
Comparing APP expression between groupsFDR
B-cell VS CAF2.41142069074637e-10
B-cell VS Endothelial cell1.06024897028429e-05
B-cell VS Macrophage0.00036393963179363
B-cell VS T-cellNS
B-cell VS melanoma tumorNS
B-cell VS melanoma1.198950288818e-27
B-cell VS unresolved5.3957795764058e-06
CAF VS Endothelial cell6.17292358789126e-10
CAF VS Macrophage0.00114934310381325
CAF VS T-cell2.39861776854852e-09
CAF VS melanoma tumor1.71964075905473e-06
CAF VS melanomaNS
CAF VS unresolved0.0224026357219156
Endothelial cell VS Macrophage1.26868647001658e-10
Endothelial cell VS T-cell1.16231701424426e-05
Endothelial cell VS melanoma tumor9.44467136092978e-06
Endothelial cell VS melanoma3.80124979337004e-13
Endothelial cell VS unresolved1.69908634654449e-05
Macrophage VS T-cell0.00211936907177496
Macrophage VS melanoma tumor0.00532307179178654
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for APP

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 B-cell[326]
 CAF[39]
 Endothelial cell[40]
 Macrophage[42]
 melanoma[1071]
 melanoma tumor[246]
 T-cell[1302]
 unresolved[96]